Results 121 to 130 of about 699,324 (261)
9,10-Dioxa-1,2-diaza-anthracene derivatives from tetrafluoropyridazine
Beilstein Journal of Organic Chemistry, 2010 Reaction of tetrafluoropyridazine with catechol gives a tricyclic 9,10-dioxa-1,2-diaza-anthracene system by a sequential nucleophilic aromatic substitution ring annelation process, further extending the use of perfluoroheteroaromatic derivatives for the ...
Graham Pattison +5 more
doaj +1 more source
Angewandte Chemie, EarlyView.Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani +7 more
wiley +2 more sources
Functionalized N-Aryl-Substituted Cyclens by Nucleophilic Aromatic Substitution
, 2005 The reaction of trifold protected cyclen with fluorinated dinitroarenes yields aryl-substituted or aryl-bridged cyclen derivatives in good yield.
Subat, M. +3 more
core +1 more source
Rational design of a "dual lock-and-key" supramolecular photosensitizer based on aromatic nucleophilic substitution for specific and enhanced photodynamic therapy. [PDF]
Chem Sci, 2020 Teng KX, Niu LY, Kang YF, Yang QZ.
europepmc +1 more source
1,2‐Bis(boronate) Arenes by Borylation Directed Borylation
Angewandte Chemie, EarlyView.Boron electrophiles derived from tetrabromo‐pyrazaboles and AlCl3 affect the regioselective vicinal double C–H borylation of a range of arenes and polycyclic aromatic hydrocarbons (PAHs). A subsequent pinacol installation step then affords the vicinal bis‐boronate ester‐substituted arene/PAH.
Anna V. Schellbach +4 more
wiley +2 more sources
Angewandte Chemie, EarlyView.Gal‐SeNBD‐oleamide is an activatable photosensitizer (PS) with efficient uptake and selective, β‐galactosidase‐triggered activation in cancer cells, enabling efficient photodynamic ablation of glioma cells directly in brain tissue slices from mouse preclinical models and human glioblastoma patients.
Utsa Karmakar +18 more
wiley +2 more sources
A mechanistic continuum of nucleophilic aromatic substitution reactions with azole nucleophiles
Chemical ScienceNucleophilic aromatic substitution reactions between indoles and aryl fluorides proceed by a general-base-catalyzed borderline mechanism and appear to lie on a mechanistic continuum.
Harrison W. Toll +8 more
openaire +2 more sources
Cobalt‐Catalyzed [2σ+2π] Cycloaddition via Site‐Selective Capture of Bicyclobutane Diradical
Angewandte Chemie, EarlyView.We report a Co(II)‐catalyzed strategy that combines thermal activation of bicyclo[1.1.0]butane (BCBs) with site‐selective radical capture to furnish head‐to‐head fused bicyclo[2.1.1]hexanes via [2σ+2π] cycloaddition with indoles. Detailed mechanistic studies (31P NMR, EPR, CV, and DFT) support the catalytic pathway, while phosphine‐oxide trapping and X‐
Tanmayee Nanda +8 more
wiley +2 more sources
Angewandte Chemie, EarlyView.Driven by sodium dithionite and hydrogen peroxide under mild aqueous conditions, a water‐soluble perylene bisimide undergoes reversible electron‐transfer cycles that generate its emissive excited state without dye decomposition. We define this out‐of‐equilibrium system as chemically fueled regenerative chemiluminescence (CFRCL), opening new avenues for
Luca Morgan +5 more
wiley +2 more sources
Predicting Regioselectivity in Nucleophilic Aromatic Substitution
, 2016 We have investigated practical and computationally efficient methods for the quantitative prediction of regioisomer distribution in kinetically controlled nucleophilic aromatic substitution reactions.
Simone Tomasi (139458) +5 more
core +1 more source