Results 171 to 180 of about 597,754 (265)

Regioselective approach to 5-arylsulfonylisoxazoles and their antimicrobial activity. [PDF]

Beilstein J Org Chem
Sazonov AS, Vasilenko DA, Porfiriev DV, Grishin YK, Gazzaeva RA, Chernyshova AP, Kryakvin MA, Baranova AA, Alferova VA, Averina EB.   +9 more
europepmc   +1 more source

Organelle‐Resolved Tetrazine‐trans‐Cyclooctene Click Chemistry for Cargo Delivery and Release

Chemistry – A European Journal, EarlyView.
Bioorthogonal click chemistry tools provide a means for specific intracellular conjugation of molecules. In this study, we used reactive tetrazine (Tz) and TCO moieties for labeling of organelles and organelle‐specific delivery and activation of doxorubicin prodrugs.
Oleh Durydivka, Marek Chovanec, Rastislav Dzijak, Michal Rahm, Jachym Hrusak, Paul E. Reyes‐Gutierrez, Milan Vrabel   +6 more
wiley   +1 more source

<i>O</i>-Heterocycles-Fused Indoles via Tandem 1,2-Indole Migration-Hydroxycyclization Reactions in 2-Hydroxyalkyl-3-propargylindoles. [PDF]

Org Lett
Renedo L, Solas M, Silva López C, Suárez-Pantiga S, Sanz R.   +4 more
europepmc   +1 more source

Organocatalytic Formal (3+2+1)‐Cycloaddition of Allenoates, Michael Acceptors, and Carbaldehydes

Chemistry – A European Journal, EarlyView.
The use of secondary amine Lewis base organocatalysts allows for the unprecedented activation of allenoates for formal (3+2+1)‐cycloadditions with Michael acceptors and aromatic carbaldehydes. ABSTRACT Employing secondary amines as covalently interacting Lewis basic organocatalysts allows for the activation of electron‐deficient allenes (allenoates ...
David Naderer, Alexander Pötscher, Katharina Eder, Uwe Monkowius, Markus Himmelsbach, Mario Waser   +5 more
wiley   +1 more source

Hydrogen-Bond-Assisted Hydroxylation of <i>o</i>-Fluorobenzamides: A Transition-Metal-Free Approach to Salicylamides. [PDF]

Molecules
Chen T, Lei H, Huang T, Chen H, Li S, Liu F, Xu HC, Shen J.   +7 more
europepmc   +1 more source

Substituent‐Dependent Structural Trends in Thermal Condensation of Silanetriols and Disiloxanetetraols

Chemistry – A European Journal, EarlyView.
We report a catalyst‐ and solvent‐free thermal condensation route to oligosilsesquioxanes from arylsilanetriols and disiloxanetetraols. Phenyl and 1‐naphthyl systems form ladder‐like structures, while 2‐naphthyl systems yields layered architectures.
Jan‐Falk Kannengießer, Svenja Pohl, Bernd Morgenstern, Oliver Janka, Guido Kickelbick   +4 more
wiley   +1 more source

Radical "Link-and-Lose" Strategies for Iterative C-F Functionalization of Polyfluoroarenes. [PDF]

Chem
Sharma P, Weaver JD.
europepmc   +1 more source

Oxidative Generation and Reactivity of the Cyclopropyl Radical From a Martin Silicate

Chemistry – A European Journal, EarlyView.
A photoredox strategy employing Martin silicates enables the oxidative generation and controlled capture of cyclopropyl radicals, including the naked one, long considered challenging intermediates. The method affords functionalized cyclopropanes through both Giese‐type additions and dual nickel/photoredox C(sp3)−C(sp2) cross‐couplings.
Amal Lakhal, Alexandre Millanvois, Louis Fensterbank, Cyril Ollivier   +3 more
wiley   +1 more source

Room-Temperature Decarboxylative Amination of Electron-Deficient (Hetero)Aromatic Carboxylic Acids. [PDF]

Org Lett
Basnet R, Golian K, Sampson J, Hoover JM.   +3 more
europepmc   +1 more source

Stereoretentive Nucleophilic Aromatic Substitution Accesses Atropisomeric 4‐Amino‐N‐Arylquinolinium Salts

Chemistry – A European Journal, EarlyView.
Quinolin‐4‐ones were converted to chloroquinolinium salts, allowing formation of axially chiral aminoquinolinium salts via an enantioretentive SNAr reaction with a variety of amine nucleophiles. The salts have a high rotational barrier, with a racemization half‐life of ∼1000s of years.
Darren Holmes, Nia Foster, Saima Ansari, Paul Kavanagh, Paul Dingwall, Peter C. Knipe   +5 more
wiley   +1 more source