Results 181 to 190 of about 699,324 (261)

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, EarlyView.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

Automated Parallel Synthesis Accelerates Virtual Screening Hit Discovery. [PDF]

J Am Chem Soc
McKenna SM, Šícho M, van der Horst C, Maasland J, van der Nol E, Turco G, Bernatavicius A, van Westen GJP, Heitman LH, Pomplun SJ.   +9 more
europepmc   +1 more source

RhodaMal Dyes: Novel Red Emissive Fluorophores as Probes for High Contrast Live‐Cell Imaging

Chemistry – A European Journal, EarlyView.
Incorporation of malononitrile into the traditional rhodol framework furnishes RhodaMal (Rhoda = Rhodamine, Mal = Malononitrile;) dyes, a new class of red emissive push–pull chromophores. Conjugating them to triphenylphosphonium cation enables live cell super‐resolution STED microscopy with a 775 nm depletion laser.
A. Mavroskoufis, P. Aßmann, L. M. Filla, I. Bilici, E. Quaas, M. Maglione, S. Sigrist, R. Haag, K. Licha   +8 more
wiley   +1 more source

Metal-Free Electrochemical Construction of Oxygen Heterocycles. [PDF]

Acc Chem Res
Valdés H, Batanero B.
europepmc   +1 more source

Chiral Pyrazolinylidene Complexes for Asymmetric Catalysis

Chemistry – A European Journal, EarlyView.
The synthesis and application of pyrazolin‐5‐ylidene NHC chiral‐at‐ruthenium catalysts is reported. The strong donating pyrazolin‐5‐ylidene ligands led to highly electron rich ruthenium complexes, which showed excellent catalytic activity and enantioselectivity in the intramolecular aziridination of an alkene.
Felix Möller, Nemrud Demirel, Thomas Krüger, Linus Plohnke, Jennifer Schröder, Sergei I. Ivlev, Eric Meggers   +6 more
wiley   +1 more source

Iron-Catalyzed Nucleophilic Substitution Reactions: An Overview. [PDF]

ACS Omega
Ramamoorthy S, Ramasubramanian M, Sivaraj N, Dohi T, Singh FV.   +4 more
europepmc   +1 more source

Synthesis and Structures of Novel Chiral Cyclic Hypervalent Iodine(III) Reagents for Metal‐Free Ligand‐Transfer Reactions

Chemistry – A European Journal, EarlyView.
Several new chiral cyclic hypervalent iodine(III) reagents have been synthesized and characterized. Carbon‐based ligands were successfully installed onto the hypervalent iodine centers, giving thus access to novel chiral cyano‐, trifluoromethyl‐ or alkynyl‐bearing λ3‐iodanes.
Emmanuel Valzer, Jean‐Marc Sotiropoulos, Karinne Miqueu, Laurent Pouységu, Stéphane Quideau   +4 more
wiley   +1 more source

From Charge‐Transfer Adducts to (Tri)Halide‐Templated Supramolecular Cages: Covalent vs Ionic Products in the Reactions of Pyridin‐4‐ylthio‐Substituted Tetrathiafulvalene With Dihalogens and Interhalogens

Chemistry – A European Journal, EarlyView.
The reactions between tetra(pyridin‐4‐ylthio)tetrathiafulvalene and Br2/I2/ICl/IBr led to a variety of products, including a rare example of neutral 1:4 CT adduct and ionic products showing supramolecular cage motifs at (tri)halide templates. The nature of the reaction products was elucidated based on XRD analysis, Raman spectroscopy and QTAIM, NCI ...
Anna Caria, Stéphane A. Baudron, M. Carla Aragoni, Vito Lippolis, Anna Pintus, Enrico Podda, Massimiliano Arca   +6 more
wiley   +1 more source

FDA-Approved Drugs Containing Amide Functionality in the Last Five Years (2021-2025): Pharmaceutical Use, Trends and Synthetic Approaches. [PDF]

Medicines (Basel)
Benedetto Tiz D.
europepmc   +1 more source