Results 191 to 200 of about 699,324 (261)

N‐Sulfonyl Azalevoglucosan: A Versatile Platform for the Synthesis of Polysubstituted Piperidines

Chemistry – A European Journal, EarlyView.
Gain by strain: The synthesis of a levoglucosan analog, in which the pyranose oxygen has been replaced by a nitrogen, allows navigation on the piperidine ring to iteratively install functional groups at C1, C2, C3, C4, and C6 positions using simple experimental protocols with minimal protecting group manipulation.
Dylan Yorga, Jérôme Marrot, Ana Poveda, Nicolas Auberger, Jesús Jiménez‐Barbero, Jérôme Désiré, Yves Blériot   +6 more
wiley   +1 more source

Catalytically Promiscuous PLP-Dependent Aminotransferases Are Biocatalysts for C-C Bond Formation. [PDF]

ACS Cent Sci
Kim AT, Howard JR, Cuba Cáceres AG, Chong KI, Aye WA, Sigman MS, Narayan ARH.   +6 more
europepmc   +1 more source

A Stable Isopterin Mimic of a Potent Bacterial Stimulant of T Cells

Chemistry – A European Journal, EarlyView.
A microbial metabolite covalently binds immunological protein MR1 to potently activate specific lymphocytes called MAIT cells, but it is too unstable for biological applications. Here, using synthesis, assays, protein crystallography, and computer modelling, we report a water‐stable analogue that activates reporter cells expressing the MAIT T cell ...
Jeffrey Y. W. Mak, Huy N. Hoang, Wael Awad, Xin Yi Lim, Damica D. Laurie, Ryan J. D. Rivero, James McCluskey, Alexandra J. Corbett, Jamie Rossjohn, David P. Fairlie   +9 more
wiley   +1 more source

Self‐Immolative Poly(Benzyl Ether)s: Design Principles and Controlled Depolymerization

Chemistry – A European Journal, EarlyView.
Unzipping to Sustainability: This Concept article explores the thermodynamic design of quinone‐methide (QM)‐based poly(benzyl ether)s (PBEs). It explains how a low ceiling temperature (Tc), QM stability, and an entropic gain drive rapid depolymerization (“unzipping”) of PBEs into monomers.
Ji Woo Kim, Yewon Kang, Hyungwoo Kim
wiley   +1 more source

Recent advances in [¹¹C]HCN radiochemistry and applications to (pre)clinical PET imaging. [PDF]

Nucl Med Biol
McCarthy CJ, Scott PJH.
europepmc   +1 more source

The Radical Chemistry of 2,3‐Diguanidinopyridines: Coordination and Visible‐Light Photochemistry

Chemistry – A European Journal, EarlyView.
Substitution at the pyridine core of 2,3‐diguanidinopyridines was used to develop novel redox‐active molecules with three interconvertible redox states. They are applied as redox‐active ligands in coordination chemistry. Visible‐light irradiation of the pyridine N‐benzylated molecules leads to photoconversion to a higher‐energetic isomer.
Hanna Koepcke, Etienne Engels, Elisabeth Kaifer, Hans‐Jörg Himmel   +3 more
wiley   +1 more source

An undecacyclic carbon-centered hydrocarbon radical: synthesis and investigation. [PDF]

Beilstein J Org Chem
Acan AS, Werner J, Podlech J.
europepmc   +1 more source

N‐Boron‐Functionalized Anionic N‐Heterocyclic Carbenes (NBA‐NHCs)—A Case Study

Chemistry – A European Journal, EarlyView.
The synthesis and characterization of a new family of N‐boron‐functionalized anionic N‐heterocyclic carbenes (NBA‐NHCs), IiPrB(CN)3−, IiPr(C2F5)BF2−, IMesB(CN)3−, and IMes(C2F5)BF2−, is reported. ABSTRACT The synthesis and characterization of a new family of N‐boron‐functionalized anionic NHCs (NBA‐NHCs), IiPrB(CN)3− (5), IiPr(C2F5)BF2− (6), IMesB(CN)3−
Sophie Mann, Günther Horrer, Maik Finze, Udo Radius   +3 more
wiley   +1 more source

Molecular engineering of bistetrafluoropyridine aryl ethers: a general platform for stable and programmable amorphous organic solids. [PDF]

RSC Adv
Weeks NJ, Speicher AA, Iacono ST.
europepmc   +1 more source

Catalytic asymmetric formal nucleophilic C2-substitution of indoles via C2-umpolung toward 2,3'-bisindole atropisomers. [PDF]

Nat Commun
Gao CH, Yu XY, Yao BX, Yu HL, Ni SF, Tan W, Shi F.   +6 more
europepmc   +1 more source