Results 1 to 10 of about 4,415 (139)

Common molecular profile of multiple structurally distinct warfare arsenicals in causing cutaneous chemical vesicant injury [PDF]

Scientific Reports
Skin exposure to arsenicals such as lewisite and phenylarsine oxide leads to severe cutaneous damage. Here, we characterized the molecular pathogenesis of skin injury caused by additionally structurally distinct warfare arsenicals including ...
Ritesh Kumar Srivastava, Suhail Muzaffar, Jasim Khan, Mohit Bansal, Anupam Agarwal, Mohammad Athar   +5 more
doaj   +2 more sources

Adsorption Characteristics of Dimethylated Arsenicals on Iron Oxide–Modified Rice Husk Biochar [PDF]

Toxics, 2022
In this study, the adsorption characteristics of dimethylated arsenicals to rice husk biochar (BC) and Fe/biochar composite (FeBC) were assessed through isothermal adsorption experiments and X-ray absorption spectroscopy analysis.
Sang-Gyu Yoon, Ihn-Sil Kwak, Hye-On Yoon, Jinsung An   +3 more
doaj   +2 more sources

Emulsome-Based Nanocarrier System for Controlled 4-Phenylbutyric Acid Delivery and Mechanistic Mitigation of Arsenical-Induced Skin Injury via Foam Application [PDF]

Pharmaceutics
Background: Lewisite, a potent chemical warfare agent, induces rapid and progressive cutaneous damage, necessitating treatment strategies that offer both immediate decontamination and prolonged therapeutic action. This study aimed to develop and evaluate
Nethra Viswaroopan, Meheli Ghosh, Sharvari M. Kshirsagar, Jasim Khan, Jennifer Toral-Orduno, Ritesh K. Srivastava, Mohammad Athar, Ajay K. Banga   +7 more
doaj   +2 more sources

Construction of a Novel 3D Urinary Bladder Mucosa Model and Its Application in Toxicity Assessment of Arsenicals [PDF]

Toxics
The urinary bladder is a primary target organ for environmental toxicants such as arsenic. The objects of this study were two-fold. First, we constructed a novel 3D urinary bladder mucosa model (3D-UBMM) composed of an overlying epithelium and a ...
Runjie Guo, Min Gi, Tohru Kiyono, Arpamas Vachiraarunwong, Shugo Suzuki, Masaki Fujioka, Guiyu Qiu, Kwanchanok Praseatsook, Yurina Kawamura, Anna Kakehashi, Ikue Noura, Xiaoli Xie, Hideki Wanibuchi   +12 more
doaj   +2 more sources

Persistent neutrophilic inflammation is associated with delayed toxicity of phenylarsine oxide in lungs [PDF]

Scientific Reports
Phenyl arsine oxide (PAO) is a vesicant, similar to Lewisite, a potential chemical warfare agent and an environmental contaminant. PAO-induced skin burns can trigger acute organ injury, including lungs.
Nilda C. Sanchez, Gopikrishnan Mani, Joanna I. Nowak, Carlin Jones, Young-il Kim, Nirmal S. Sharma, Jaroslaw W. Zmijewski, Ranu Surolia   +7 more
doaj   +2 more sources

Synergistic effects of Fe-Mn binary oxide for gaseous arsenic removal in flue gas

Ecotoxicology and Environmental Safety, 2021
High-efficient and economic sorbents are highly desired for arsenic (As) emission control in flue gas from coal-fired power plant. A series of Fe-Mn binary oxides were prepared by a facile method, and their behaviors for gaseous arsenic removal in flue ...
Kai-Qiang He, Chun-Gang Yuan, Yang-Hong Jiang, Xue-Lei Duan, Yan Li, Meng-Dan Shi   +5 more
doaj   +1 more source

Experimental toxicity study of orally ingested detoxified Manashila (realgar) treated in liquid herbal and animal drugs

Journal of Ayurveda, 2023
Introduction: Manashila (reaglar) is one of the arsenicals used in traditional ayurvedic treatments to treat various respiratory, neurological, and skin manifestations.
Madhuri S Pawar, Deepali Suryawanshi, Priti Dhande   +2 more
doaj   +1 more source

Carbohydrate-Containing Low Molecular Weight Metabolites of Microalgae

Marine Drugs, 2023
Microalgae are abundant components of the biosphere rich in low molecular weight carbohydrate-containing natural products (glycoconjugates). Glycoconjugates take part in the processes of photosynthesis, provide producers with important biological ...
Valentin A. Stonik, Inna V. Stonik
doaj   +1 more source

Dynamic Regulation of the Nexus Between Stress Granules, Roquin, and Regnase-1 Underlies the Molecular Pathogenesis of Warfare Vesicants

Frontiers in Immunology, 2022
The use of chemical warfare agents is prohibited but they have been used in recent Middle Eastern conflicts. Their accidental exposure (e.g. arsenical lewisite) is also known and causes extensive painful cutaneous injury.
Ritesh Kumar Srivastava, Bharat Mishra, Suhail Muzaffar, Marina S. Gorbatyuk, Anupam Agarwal, Anupam Agarwal, M. Shahid Mukhtar, Mohammad Athar   +7 more
doaj   +1 more source

Exposure to arsenic and level of Vitamin D influence the number of Th17 cells and production of IL-17A in human peripheral blood mononuclear cells in adults

PLoS ONE, 2022
There is limited evidence on the effects of environmental exposure to arsenic (As) on the immune system in adults. In a population-based study, we have found that urinary As (UAs), and its metabolites [inorganic As (InAs), monomethylated arsenicals (MMA ...
Faruque Parvez, Fredine T. Lauer, Pam Factor-Litvak, Tariqul Islam, Mahbubul Eunus, M. Abu Horayara, Mizanour Rahman, Golam Sarwar, Habibul Ahsan, Joseph H. Graziano, Scott W. Burchiel   +10 more
doaj   +2 more sources