Results 61 to 70 of about 7,763 (163)

Clinical Pharmacokinetics and Pharmacodynamics of Artemether-Lumefantrine

Clinical Pharmacokinetics, 1999
The combination of artemether and lumefantrine (benflumetol) is a new and very well tolerated oral antimalarial drug effective even against multidrug-resistant falciparum malaria. The artemether component is absorbed rapidly and biotransformed to dihydroartemisinin, and both are eliminated with terminal half-lives of around 1 hour.
White, N, van Vugt, M, Ezzet, F
openaire   +2 more sources

Therapeutic efficacy of artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Ethiopia: a systematic review and meta-analysis

Infectious Diseases of Poverty, 2017
Background As Ethiopia is one of the sub-Saharan countries with a great burden of malaria the effectiveness of first line anti-malarial drugs is the major concern.
Mohammed Biset Ayalew
doaj   +1 more source

Comparative in vitro dissolution profiles of marketed Artemether–Lumefantrine adult-dose tablets in Kinshasa, Democratic Republic of the Congo

Orapuh Journal
Introduction Despite advances in clinical care, therapeutic strategies, and governmental interventions, malaria remains a significant public health concern—particularly in Africa, which consistently ranks highest in global morbidity and mortality ...
Gloria Bujo Dhimbe, Dadit Ive Kitenge, Emile Tweny Baruti, Jocelyn Mankulu Kakumba, Jérémie Mbinze   +4 more
doaj   +1 more source

Pharmacokinetics of artemether and dihydroartemisinin in healthy Pakistani male volunteers treated with artemether-lumefantrine

Malaria Journal, 2010
Background Artemether-lumefantrine is one of the most widely used anti-malarial drug combinations in the world with excellent tolerability and cure rates in adult and paediatric patients with uncomplicated falciparum malaria. The aim of this study was to
Tarning Joel, Najmi Muzammil H, Ali Shabana, Lindegardh Niklas   +3 more
doaj   +1 more source

Knowledge among drug dispensers and antimalarial drug prescribing practices in public health facilities in Dar es Salaam

Drug, Healthcare and Patient Safety, 2013
Appolinary AR Kamuhabwa,1 Richard Silumbe21Unit of Pharmacology and Therapeutics, School of Pharmacy, Muhimbili University of Health and Allied Sciences, 2Pharmacy Council, Dar es Salaam, TanzaniaBackground: Irrational prescribing and dispensing of ...
Kamuhabwa AA, Silumbe R
doaj  

Artemether–lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria

Therapeutics and Clinical Risk Management, 2009
Stephan Ehrhardt, Christian G MeyerBernhard Nocht Institute for Tropical Medicine, Tropical Medicine Section, Hamburg, GermanyAbstract: The World Health Organization strongly recommends artemisinin-based combination therapy (ACT) regimens for the ...
Stephan Ehrhardt, Christian G Meyer
doaj  

Two Imported Malaria Cases with Delayed Response to Treatment in Hatay

Türkiye Parazitoloji Dergisi
The study presents two imported malaria cases with a history of travel to malaria-endemic areas and replied late response to treatment. In the blood preparations of the first case, dot-shaped nucleus structures were identified in the erythrocytes, which ...
Tuğba Kaya, Mehmet Çabalak, Gülnaz Çulha, Ceren Ünal   +3 more
doaj   +1 more source

Implementation of artemether-lumefantrine treatment policy for malaria at health facilities in Tanzania

Risk Management and Healthcare Policy, 2011
V Mugoyela1, O Minzi21Department of Medicinal Chemistry, 2Unit of Pharmacology and Therapeutics, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar Es Salaam, TanzaniaBackground: The purpose of this study was to compare knowledge
Mugoyela V, Minzi 0
doaj  

Update on the efficacy, effectiveness and safety of artemether–lumefantrine combination therapy for treatment of uncomplicated malaria

Therapeutics and Clinical Risk Management, 2009
Pauline Byakika-Kibwika1,2, Mohammed Lamorde1,2, Harriet Mayanja-Kizza1, Concepta Merry1,2, Bob Colebunders3,4, Jean-Pierre Van geertruyden4,51Infectious Diseases Institute and Infectious Diseases Network for Treatment and Research in Africa (INTERACT ...
Pauline Byakika-Kibwika, Mohammed Lamorde, Harriet Mayanja-Kizza, et al   +3 more
doaj  

Experimental Evolution of Reduced Susceptibility to Artemether-Lumefantrine in <i>Plasmodium berghei</i> Following Serial Drug Pressure. [PDF]

J Parasitol Res
Njoroge SM, Kimani SK, Ngonjo TW, Olunga MS, Seng Ete Wambua J, Waithera MW, Wawa HY, Ng Ang A Waweru J.   +7 more
europepmc   +1 more source