Results 11 to 20 of about 63,940 (276)
Postgraduate Medical Journal, 2005 Artemisinins were discovered to be highly effective antimalarial drugs shortly after the isolation of the parent artemisinin in 1971 in China. These compounds combine potent, rapid antimalarial activity with a wide therapeutic index and an absence of ...
Haynes, RK, Krishna, S, Woodrow, CJ
core +7 more sources
Chemie in unserer Zeit, 2014 AbstractArtemisinin ist der modernste Wirkstoff gegen Malaria, eine Infektionskrankheit, die den Menschen durch seine gesamte Entwicklungsgeschichte begleitete. Experimentelle Hinweise auf antike Malaria‐Epidemien gelangen durch Vervielfältigung von DNA‐Fragmenten des Erregers mit Hilfe der Polymerasekettenreaktion und dem Abgleich mit dem inzwischen ...
Paul May, Simon Cotton
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A Major Genome Region Underlying Artemisinin Resistance in Malaria
Science, 2012 Ian H Cheeseman +2 more
exaly +3 more sources
BMC Complementary Medicine and Therapies, 2022 Background Novel Corona Virus Disease 2019 (COVID-19) is closely associated with cytokines storms. The Chinese medicinal herb Artemisia annua L. (A. annua) has been traditionally used to control many inflammatory diseases, such as malaria and rheumatoid ...
Yexiao Tang +9 more
doaj +1 more source
Garcinia Biflavonoid 1 Improves Lipid Metabolism in HepG2 Cells via Regulating PPARα
Molecules, 2022 Garcinia biflavonoid 1 (GB1) is one of the active chemical components of Garcinia kola and is reported to be capable of reducing the intracellular lipid deposition, which is the most significant characteristic of non-alcoholic fatty liver disease ...
Hai-Xin Chen +7 more
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BMC Complementary Medicine and Therapies, 2022 Background: The WHO recommends artemisinin-based combination regimens for uncomplicated Plasmodium falciparum malaria. One such combination is artemisinin-piperaquine tablets (ATQ).
Xiaobo Li +9 more
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Frontiers in Pharmacology, 2022 The WHO recommends Artemisinin-based combination therapy (ACTs) as the first-line treatment for malaria. This meta-analysis aims to analyze the effects of artemisinin and its derivatives as well as non-artemisinin drugs on the gametophytes in the host ...
Yuanyuan Zou +16 more
doaj +1 more source
Antimicrobial Agents and Chemotherapy, 2003 A recent Letter to the Editor (R. K. Haynes, D. Monti, D. Taramelli, N. Basilico, S. Parapini, and P. Olliaro, Letter, Antimicrob. Agents Chemother. 47:1175, 2003) presented cogent evidence that artemisinin and its derivatives do not inhibit hemozoin formation in vitro.
Haynes, Richard K. +5 more
openaire +5 more sources
Journal of Nanobiotechnology, 2023 Background Malaria remains a serious threat to global public health. With poor efficacies of vaccines and the emergence of drug resistance, novel strategies to control malaria are urgently needed.
Zhouqing He +13 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Vanillic acid, a phenolic compound mainly obtained from the foot of Picrorhiza scrophulariiflora Pennell, has been demonstrated to possess a cardiovascular-protective effect in previous studies.
Manxue Mei +8 more
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