Results 21 to 30 of about 28,538 (185)

GB1a Ameliorates Ulcerative Colitis via Regulation of the NF-κB and Nrf2 Signaling Pathways in an Experimental Model

Frontiers in Medicine, 2021
Ulcerative colitis (UC) is an inflammatory bowel disease. The intake of African Garcinia Kola nuts has been reported as a therapy for diarrhea and dysentery in the African population.
Yuanyuan Yu, Congmin Zheng, Xu Lu, Changsheng Deng, Changsheng Deng, Qin Xu, Qin Xu, Wenfeng Guo, Wenfeng Guo, Qingye Wu, Qi Wang, Changhui Liu, Xinan Huang, Xinan Huang, Jianping Song, Jianping Song   +15 more
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China's foreign aid for global poverty alleviation: artemisinin-based combination therapies against malaria in Togo

Global Health Journal, 2021
From providing funds for the global fight against infectious diseases, to actively participating in global health security actions, to strengthening mutual cooperation in the field of health, and providing medical treatment, training and scholarships to ...
Qi Wang, Chuyi Yu, Hongying Zhang, Shaoqin Zheng, Jianping Song, Changsheng Deng   +5 more
doaj   +1 more source

Development of artesunate intelligent prodrug liposomes based on mitochondrial targeting strategy

Journal of Nanobiotechnology, 2022
Breast cancer is the leading cause of cancer-related deaths in women and remains a formidable therapeutic challenge. Mitochondria participate in a myriad of essential cellular processes, such as metabolism, and are becoming an ideal target for cancer ...
Liwei Gu, Jiaxing Zhang, Dandan Liu, Jiayun Chen, Shuzhi Liu, Qing Peng, Ya Tian, Maobo Du, Junzhe Zhang, Wei Xiao, Shuo Shen, Jigang Wang   +11 more
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Transcriptome and Lipid Metabolomics-Based Discovery: Glycyrrhizic Acid Alleviates Tripterygium Glycoside Tablet-Induced Acute Liver Injury by Regulating the Activities of CYP and the Metabolism of Phosphoglycerides

Frontiers in Pharmacology, 2022
Background: Glycyrrhizic acid (GA) has been reported to be liver protective; however, the characters and underlying mechanisms of GA against tripterygium glycoside tablet (TGT)-induced acute liver injury remain unelucidated.Hypothesis/Purpose: We assumed
Qiaoli Shi, Qixin Wang, Jiayun Chen, Fei Xia, Chong Qiu, Min Li, Minghong Zhao, Minghong Zhao, Qian Zhang, Piao Luo, Tianming Lu, Ying Zhang, Liting Xu, Xueling He, Tianyu Zhong, Tianyu Zhong, Na Lin, Qiuyan Guo   +17 more
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Acute and subacute oral toxicity assessment of Gancao Xiexin decoction in Sprague-Dawley rats

Frontiers in Pharmacology, 2023
Gancao Xiexin decoction (GCXXD), a well-known classic traditional Chinese medicine prescription, is used to treat various oral ulcers, Behcet disease, gastrointestinal ulcers, etc. However, there is very little information on its safety. This study aimed
Li Ru, Li Ru, Ruotong Liu, Haoyu Xing, Yueming Yuan, Yueming Yuan, Zheng Yuan, Zhiyong Xu, Qin Xu, Jianping Song, Xiaobo Li, Xiaobo Li, Xiaobo Li   +12 more
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Making artemisinin☆

Phytochemistry, 2008
The possibilities for the production of the antimalarial artemisinin by biological and chemical means are explored. These include native biosynthesis, genetic modification of Artemisia annua and other plants, engineering of microbes, total and partial chemical synthesis and combinations of the above.
openaire   +3 more sources

Preparation and application of calcium phosphate nanocarriers in drug delivery

Materials Today Bio, 2022
Calcium phosphate nanoparticles represent promising materials for drug delivery because of its favorable properties, including biocompatibility, biodegradability and strong affinity for binding to nucleic acids (pDNA, siRNA, miRNA, etc.) and therapeutic ...
Chong Qiu, Yanyan Wu, Qiuyan Guo, Qiaoli Shi, Junzhe Zhang, Yuqing Meng, Fei Xia, Jigang Wang   +7 more
doaj   +1 more source

Shengmai Yin alleviated plaque vulnerability and ischemic myocardial damage in diesel exhaust particle-aggravated atherosclerosis with myocardial ischemia

Ecotoxicology and Environmental Safety, 2022
Exposure to diesel exhaust particles (DEP) increases the risk of ischemic heart disease, especially heart attacks and ischemic/thrombotic strokes. Shengmai Yin (SMY) is a traditional Chinese medicine used to treat coronary heart disease.
Shuiqing Qu, Shuoqiu Deng, Ting Yang, Yuanmin Yang, Yu Zhang, Zhongyuan Zheng, Lina Chen, Yujie Li   +7 more
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Identification of antimalarial targets of chloroquine by a combined deconvolution strategy of ABPP and MS-CETSA

Military Medical Research, 2022
Background Malaria is a devastating infectious disease that disproportionally threatens hundreds of millions of people in developing countries. In the history of anti-malaria campaign, chloroquine (CQ) has played an indispensable role, however, its ...
Peng Gao, Yan-Qing Liu, Wei Xiao, Fei Xia, Jia-Yun Chen, Li-Wei Gu, Fan Yang, Liu-Hai Zheng, Jun-Zhe Zhang, Qian Zhang, Zhi-Jie Li, Yu-Qing Meng, Yong-Ping Zhu, Huan Tang, Qiao-Li Shi, Qiu-Yan Guo, Ying Zhang, Cheng-Chao Xu, Ling-Yun Dai, Ji-Gang Wang   +19 more
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MnUA–DOX–artesunate hydrogel remodels immunosuppressive tumor microenvironment and prevents postoperative recurrence in triple-negative breast cancer

Journal of Nanobiotechnology
Triple-negative breast cancer (TNBC) remains a formidable clinical challenge because of its high aggressiveness, metastatic potential, and lack of effective therapeutic options.
Keneng Cai, Run Xia, Mengyao Xu, Wanying Chen, Wenli Cai, Xinyu Liu, Tiantian Guo, Weichi Jiang, Chuyi Yu, Jianjia Feng, Chengli Ling, Sheng Zhou, Yinhuan Chen, Changsheng Deng, Qin Xu, Jianming Liang   +15 more
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