Results 11 to 20 of about 37,512 (201)
Artesunate repurposing for cytomegalovirus management: a systematic review of efficacy, mechanisms, and perspectives [PDF]
Frontiers in Cellular and Infection MicrobiologyBackgroundCytomegalovirus (CMV) is a prevalent opportunistic pathogen associated with significant morbidity and mortality in immunocompromised individuals, particularly transplant recipients and neonates. Current antiviral therapies are often constrained
Haohao Zhang +6 more
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Application Strategy and Research Progress of Large-Scale Population Drug Intervention in Malaria Control [PDF]
Tropical Medicine and Infectious DiseaseMalaria is one of the major global public health issues. An estimated 282 million malaria cases occurred worldwide in 2024, and the overall prevention and control progress has stagnated or even reversed in some regions. Mass drug administration (MDA), as
Zichao Cao +3 more
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A head-to-head comparison of four artemisinin-based combinations for treating uncomplicated malaria in African children: a randomized trial. [PDF]
PLoS Medicine, 2011 Artemisinin-based combination therapies (ACTs) are the mainstay for the management of uncomplicated malaria cases. However, up-to-date data able to assist sub-Saharan African countries formulating appropriate antimalarial drug policies are scarce.Between
Four Artemisinin-Based Combinations (4ABC) Study Group
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Table1_The Effect of Artemisinin-Based Drugs vs Non-artemisinin-based Drugs on Gametophyte Carrying in the Body After the Treatment of Uncomplicated Falciparum Malaria: A Systematic Review and Meta-analysis.docx [PDF]
, 2022 The WHO recommends Artemisinin-based combination therapy (ACTs) as the first-line treatment for malaria. This meta-analysis aims to analyze the effects of artemisinin and its derivatives as well as non-artemisinin drugs on the gametophytes in the host ...
Changqing Li (333970) +15 more
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Frontiers in Pharmacology, 2022 Vanillic acid, a phenolic compound mainly obtained from the foot of Picrorhiza scrophulariiflora Pennell, has been demonstrated to possess a cardiovascular-protective effect in previous studies.
Manxue Mei +8 more
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Frontiers in Pharmacology, 2020 Objective: The purpose of this meta-analysis of longitudinal studies is to determine the safety and efficacy of artesunate combined with other forms of adjunctive therapies for severe malaria.Methods: Following the PRISMA guidelines, we searched multiple
Yuanyuan Zou +18 more
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Frontiers in Pharmacology, 2020 ObjectiveThe World Health Organization recommends artemisinin-based combination therapies (ACTs) for the treatment of uncomplicated malaria to improve the therapeutic efficacy and limit the choice of drug-resistant parasites.
Qi Wang +19 more
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Proceedings of Chemistry, Pharmacology, Pharmacokinetics and Synthesis of Biflavonoids
Molecules, 2021 Biflavonoids, composed of two monoflavonoid residues, occur naturally in angiosperms, bryophytes, ferns, and gymnosperms. More than 592 biflavonoids have been structurally elucidated, and they can be classified into two groups of C-C and C-linear ...
Xinqian He, Fan Yang, Xin’an Huang
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Preprint: Artemisinin inhibits innate immune cell chemotaxis, cytokine production and NET release [PDF]
, 2022 Immune cell chemotaxis to the sites of pathogen invasion is critical for fighting infection, but in life-threatening conditions such as sepsis and Covid-19, excess activation of the innate immune system is thought to cause a damaging invasion of immune ...
Vilar, B. +7 more
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Frontiers in Pharmacology, 2020 BackgroundMalaria is a major public health concern in Togo. The Est-Mono district of Togo has a population of 150,000. Accordingly, the Guangzhou University of Chinese Medicine, China and the Ministry of Health and Social Security, Togo launched a ...
Qi Wang +21 more
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