Results 41 to 50 of about 63,940 (276)

Comparative genomic analysis of Artemisia argyi reveals asymmetric expansion of terpene synthases and conservation of artemisinin biosynthesis. [PDF]

Plant J
Chen X, Liao B, Wu D, Li C, Li Z, Huang Z, Duan L, Shen Q.   +7 more
europepmc   +3 more sources

Genetic and genomic approaches for the discovery of parasite genes involved in antimalarial drug resistance [PDF]

, 2013
The biggest threat to the war on malaria is the continued evolution of drug resistance by the parasite. Resistance to almost all currently available antimalarials now exists in Plasmodium falciparum which causes the most suffering among all human malaria
Mwangi, J.M., Ranford-Cartwright, L.C.
core   +1 more source

Acute and subacute oral toxicity assessment of Gancao Xiexin decoction in Sprague-Dawley rats

Frontiers in Pharmacology, 2023
Gancao Xiexin decoction (GCXXD), a well-known classic traditional Chinese medicine prescription, is used to treat various oral ulcers, Behcet disease, gastrointestinal ulcers, etc. However, there is very little information on its safety. This study aimed
Li Ru, Li Ru, Ruotong Liu, Haoyu Xing, Yueming Yuan, Yueming Yuan, Zheng Yuan, Zhiyong Xu, Qin Xu, Jianping Song, Xiaobo Li, Xiaobo Li, Xiaobo Li   +12 more
doaj   +1 more source

Adherence to the combination of sulphadoxine-pyrimethamine and artesunate in the Maheba refugee settlement, Zambia. [PDF]

, 2004
Artemisinin-based combination therapy (ACT) is one strategy recommended to increase cure rates in malaria and to contain resistance to Plasmodium falciparum. In the Maheba refugee settlement, children aged 5 years or younger with a confirmed diagnosis of
Balkan, S, Depoortere, E, Fermon, F, Guthmann, J P, Legros, D, Nkandu, E, Sipilanyambe, N   +6 more
core   +2 more sources

Socially-marketed rapid diagnostic tests and ACT in the private sector: ten years of experience in Cambodia. [PDF]

, 2011
Whilst some populations have recently experienced dramatic declines in malaria, the majority of those most at risk of Plasmodium falciparum malaria still lack access to effective treatment with artemisinin combination therapy (ACT) and others are already
A Marriot, A Talisuna, AM Dondorp, C Whitty, Cambodia National Institute of Public Health, Cambodia National Institute of Public Health, Cambodia National Institute of Public Health and Malaria Consortium, Cambodia National Institute of Public Health and National Institute of Statistics and ORC Macro, CG Kone, CIR Chandler, CS Molyneux, D Montagu, Duong Socheat, E Patouillard, E Patouillard, E Patouillard, E Rutebemberwa, Edith Patouillard, European Commission Cambodian Malaria Control Programme, G Yamey, GFATM, WHO, H Noedl, Henrietta Allen, IA Agyepong, Institute of Medicine, J Rozendaal, JD Njau, L Bury, LA Salako, Ministry of Health Department of Planning and Health Information, Ministry of Health National Centre for Parasitology, Ministry of Health National Centre for Parasitology Entomology and Malaria Control Programme, MJ Hamel, N Kikumbih, National Institute of Statistics Ministry of Planning of the Kingdom of Cambodia, O Sabot, OJ Sabot, PSI, PSI, PSI, Cambodia, RBM Task Force, RW Snow, S Incardona, S Yeung, SC McCombie, SD Foster, Shunmay Yeung, TK Ruebush, URC-MCC, WHO, World Health Organization, World Health Organization   +51 more
core   +4 more sources

Transcriptome and Lipid Metabolomics-Based Discovery: Glycyrrhizic Acid Alleviates Tripterygium Glycoside Tablet-Induced Acute Liver Injury by Regulating the Activities of CYP and the Metabolism of Phosphoglycerides

Frontiers in Pharmacology, 2022
Background: Glycyrrhizic acid (GA) has been reported to be liver protective; however, the characters and underlying mechanisms of GA against tripterygium glycoside tablet (TGT)-induced acute liver injury remain unelucidated.Hypothesis/Purpose: We assumed
Qiaoli Shi, Qixin Wang, Jiayun Chen, Fei Xia, Chong Qiu, Min Li, Minghong Zhao, Minghong Zhao, Qian Zhang, Piao Luo, Tianming Lu, Ying Zhang, Liting Xu, Xueling He, Tianyu Zhong, Tianyu Zhong, Na Lin, Qiuyan Guo   +17 more
doaj   +1 more source

Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review [PDF]

, 2018
Increasing drug resistance in gastrointestinal (GI) parasites of livestock and concerns about chemical residues in animal products and the environment are driving the development of alternative control strategies that are less reliant on the use of ...
Boas, Ulrik, Enemark, Heidi L., López-Muñoz, Rodrigo, Peña-Espinoza, Miguel, Simonsen, Henrik T., Thamsborg, Stig M., Valente, Angela H., Williams, Andrew R.   +7 more
core   +4 more sources

Recent advances in malaria genomics and epigenomics [PDF]

, 2016
Malaria continues to impose a significant disease burden on low- and middle-income countries in the tropics. However, revolutionary progress over the last 3 years in nucleic acid sequencing, reverse genetics, and post-genome analyses has generated step ...
Kirchner, Sebastian, Power, B. Joanne, Waters, Andrew P.   +2 more
core   +1 more source

Complete Chloroplast Genome Sequence and Phylogenetic Analysis of the Medicinal Plant Artemisia annua

Molecules, 2017
The complete chloroplast genome of Artemisia annua (Asteraceae), the primary source of artemisinin, was sequenced and analyzed. The A. annua cp genome is 150,995 bp, and harbors a pair of inverted repeat regions (IRa and IRb), of 24,850 bp each that ...
Xiaofeng Shen, Mingli Wu, Baosheng Liao, Zhixiang Liu, Rui Bai, Shuiming Xiao, Xiwen Li, Boli Zhang, Jiang Xu, Shilin Chen   +9 more
doaj   +1 more source

Shengmai Yin alleviated plaque vulnerability and ischemic myocardial damage in diesel exhaust particle-aggravated atherosclerosis with myocardial ischemia

Ecotoxicology and Environmental Safety, 2022
Exposure to diesel exhaust particles (DEP) increases the risk of ischemic heart disease, especially heart attacks and ischemic/thrombotic strokes. Shengmai Yin (SMY) is a traditional Chinese medicine used to treat coronary heart disease.
Shuiqing Qu, Shuoqiu Deng, Ting Yang, Yuanmin Yang, Yu Zhang, Zhongyuan Zheng, Lina Chen, Yujie Li   +7 more
doaj   +1 more source