Results 51 to 60 of about 37,512 (201)

Preparation and application of calcium phosphate nanocarriers in drug delivery

Materials Today Bio, 2022
Calcium phosphate nanoparticles represent promising materials for drug delivery because of its favorable properties, including biocompatibility, biodegradability and strong affinity for binding to nucleic acids (pDNA, siRNA, miRNA, etc.) and therapeutic ...
Chong Qiu, Yanyan Wu, Qiuyan Guo, Qiaoli Shi, Junzhe Zhang, Yuqing Meng, Fei Xia, Jigang Wang   +7 more
doaj   +1 more source

Shengmai Yin alleviated plaque vulnerability and ischemic myocardial damage in diesel exhaust particle-aggravated atherosclerosis with myocardial ischemia

Ecotoxicology and Environmental Safety, 2022
Exposure to diesel exhaust particles (DEP) increases the risk of ischemic heart disease, especially heart attacks and ischemic/thrombotic strokes. Shengmai Yin (SMY) is a traditional Chinese medicine used to treat coronary heart disease.
Shuiqing Qu, Shuoqiu Deng, Ting Yang, Yuanmin Yang, Yu Zhang, Zhongyuan Zheng, Lina Chen, Yujie Li   +7 more
doaj   +1 more source

Identification of antimalarial targets of chloroquine by a combined deconvolution strategy of ABPP and MS-CETSA

Military Medical Research, 2022
Background Malaria is a devastating infectious disease that disproportionally threatens hundreds of millions of people in developing countries. In the history of anti-malaria campaign, chloroquine (CQ) has played an indispensable role, however, its ...
Peng Gao, Yan-Qing Liu, Wei Xiao, Fei Xia, Jia-Yun Chen, Li-Wei Gu, Fan Yang, Liu-Hai Zheng, Jun-Zhe Zhang, Qian Zhang, Zhi-Jie Li, Yu-Qing Meng, Yong-Ping Zhu, Huan Tang, Qiao-Li Shi, Qiu-Yan Guo, Ying Zhang, Cheng-Chao Xu, Ling-Yun Dai, Ji-Gang Wang   +19 more
doaj   +1 more source

MnUA–DOX–artesunate hydrogel remodels immunosuppressive tumor microenvironment and prevents postoperative recurrence in triple-negative breast cancer

Journal of Nanobiotechnology
Triple-negative breast cancer (TNBC) remains a formidable clinical challenge because of its high aggressiveness, metastatic potential, and lack of effective therapeutic options.
Keneng Cai, Run Xia, Mengyao Xu, Wanying Chen, Wenli Cai, Xinyu Liu, Tiantian Guo, Weichi Jiang, Chuyi Yu, Jianjia Feng, Chengli Ling, Sheng Zhou, Yinhuan Chen, Changsheng Deng, Qin Xu, Jianming Liang   +15 more
doaj   +1 more source

Are Tanzanian patients attending public facilities or private retailers more likely to adhere to artemisinin-based combination therapy? [PDF]

, 2015
BACKGROUND: Artemisinin combination therapy (ACT) is first-line treatment for malaria in most endemic countries and is increasingly available in the private sector. Most studies on ACT adherence have been conducted in the public sector, with minimal data
Catherine Goodman, Schellenberg, David, Kalolella, Admirabilis, Katia Bruxvoort, Bruxvoort, Katia, Matthew Cairns, Festo, Charles, Charles Festo, David Schellenberg, Peter Lyaruu, S Kachur, Goodman, Catherine, Kenani, Mitya, Kachur, S Patrick, Lyaruu, Peter, Admirabilis Kalolella, Mitya Kenani, Cairns, Matthew   +17 more
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Complete Chloroplast Genome Sequence and Phylogenetic Analysis of the Medicinal Plant Artemisia annua

Molecules, 2017
The complete chloroplast genome of Artemisia annua (Asteraceae), the primary source of artemisinin, was sequenced and analyzed. The A. annua cp genome is 150,995 bp, and harbors a pair of inverted repeat regions (IRa and IRb), of 24,850 bp each that ...
Xiaofeng Shen, Mingli Wu, Baosheng Liao, Zhixiang Liu, Rui Bai, Shuiming Xiao, Xiwen Li, Boli Zhang, Jiang Xu, Shilin Chen   +9 more
doaj   +1 more source

Mass Drug Administration With Artemisinin-Piperaquine for the Elimination of Residual Foci of Malaria in São Tomé Island

Frontiers in Medicine, 2021
Background: Mass drug administration with artemisinin-piperaquine (AP-MDA) is being considered for elimination of residual foci of malaria in Democratic Republic of São Tomé and Principe.Methods: Three monthly rounds of AP-MDA were implemented from July ...
Mingqiang Li, Fei Tuo, Ruixiang Tan, Hongying Zhang, Shaoqin Zheng, Qi Wang, Qin Xu, Xinbing Yu, Fangli Lu, Zhibing Wu, Jun Huang, Herodes Sacramento Rampao, Carlos Alberto Bandeira D'almeida, Hong Yan, Jianping Song, Wenfeng Guo, Changsheng Deng   +16 more
doaj   +1 more source

Got ACTs? Availability, price, market share and provider knowledge of anti-malarial medicines in public and private sector outlets in six malaria-endemic countries. [PDF]

, 2011
BACKGROUND: Artemisinin-based combination therapy (ACT) is the first-line malaria treatment throughout most of the malaria-endemic world. Data on ACT availability, price and market share are needed to provide a firm evidence base from which to assess the
Catherine Goodman, Chapman Steven, Arogundade Ekundayo, Shewchuk Tanya, Chérifatou Bello Adjibabi, O'Connell, Kathryn A, Raharinjatovo Jacky, Agbango Jean, Hamainza Busiku, Solomon, Tsione, Rubahika Denis, Buyungo Peter, Coker Babajide, Kara Hanson, Adjibabi, Chérifatou Bello, Tsione Solomon, Jean Agbango, Coker, Babajide, Hanson, Kara, Cyprien Zinsou, Akulayi Louis, Goodman Catherine, Njogu, Julius, Erik Munroe, Hamainza, Busiku, Kathryn A O'Connell, Busiku Hamainza, Mpasela, Felton, Goodman, Catherine, Stephen Poyer, Evance Illah, Munroe Erik, Benjamin Fanomezana Ramarosandratana, Chavasse, Desmond, Mpasela Felton, Gatakaa, Hellen, Julius Njogu, Zinsou, Cyprien, Arogundade, Ekundayo, Tanya Shewchuk, Gatakaa Hellen, Evance, Illah, Raharinjatovo, Jacky, Denis Rubahika, Louis Akulayi, Njogu Julius, Babajide Coker, Hanson Kara, Ramarosandratana, Benjamin Fanomezana, Felton Mpasela, Peter Buyungo, Chapman, Steven, Shewchuk, Tanya, Hellen Gatakaa, Chavasse Desmond, Akulayi, Louis, Poyer, Stephen, Chérifatou Adjibabi, Solomon Tsione, Rubahika, Denis, Ramarosandratana Benjamin, Jacky Raharinjatovo, Munroe, Erik, Poyer Stephen, Illah Evance, Ekundayo Arogundade, Jean Angbalu Agbango, Benjamin Ramarosandratana, Steven Chapman, Agbango, Jean Angbalu, Zinsou Cyprien, O'Connell Kathryn A, Desmond Chavasse, Buyungo, Peter, Adjibabi Chérifatou   +74 more
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Metabolite Profiling of Dihydroartemisinin in Blood of Plasmodium-Infected and Healthy Mice Using UPLC-Q-TOF-MSE

Frontiers in Pharmacology, 2021
Dihydroartemisinin (DHA) and its’ derivatives have been employed as the most powerful first-line drugs for malarial treatment for several decades. The metabolism of DHA has not been studied clearly.
Yifan Zhao, Yifan Zhao, Peng Sun, Peng Sun, Yue Ma, Yue Ma, Xiaoqiang Chang, Xiaoqiang Chang, Xingyu Chen, Xingyu Chen, Xin Ji, Xin Ji, Yue Bai, Yue Bai, Dong Zhang, Dong Zhang, Lan Yang, Lan Yang   +17 more
doaj   +1 more source

Adverse drug events resulting from use of drugs with sulphonamide-containing anti-malarials and artemisinin-based ingredients: findings on incidence and household costs from three districts with routine demographic surveillance systems in rural Tanzania. [PDF]

, 2013
BACKGROUND: Anti-malarial regimens containing sulphonamide or artemisinin ingredients are widely used in malaria-endemic countries. However, evidence of the incidence of adverse drug reactions (ADR) to these drugs is limited, especially in Africa, and ...
Abdulnoor M Kabanywanyi, Catherine A Goodman, Bloland, Peter B, Abdulla, Salim M, Kapella, Bryan K, Kahigwa, Elizeus, Elizeus Kahigwa, S Kachur, Kabanywanyi, Abdulnoor M, Peter B Bloland, Kachur, S Patrick, Njau, Joseph D, Goodman, Catherine A, John E Gimnig, Gimnig, John E, Macarthur, John R, Bryan K Kapella, Joseph D Njau, John R MacArthur, Salim M Abdulla   +19 more
core   +1 more source