Results 51 to 60 of about 62,998 (285)
Journal of Experimental & Clinical Cancer Research, 2023 Background There are few effective medications for treating colorectal cancer and liver metastases (CRLM). The interactions among glycolysis, epithelial-mesenchymal transition (EMT), and immune microenvironment contribute to the progression of CRLM.
Li Long +9 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Background and Purpose: Ultrafine particulate matter (UFPM) induces oxidative stress (OS) and is considered to be a risk factor of myocardial ischemia (MI). Shengmai formula (SMF) is a traditional Chinese medicine with antioxidant properties and has been
Lina Chen +25 more
doaj +1 more source
Plant Cellular and Molecular Biotechnology: Following Mariotti's Steps [PDF]
, 2019 This review is dedicated to the memory of Prof. Domenico Mariotti, who significantly contributed to establishing the Italian research community in Agricultural Genetics and carried out the first experiments of Agrobacterium-mediated plant genetic ...
Caretto, Sofia +11 more
core +1 more source
The Genetic Wiring of Plant Trichomes: From Initiation to Fate Specification
Advanced Science, EarlyView.Plant trichomes are not just simple hairs but metabolic powerhouses shaped by complex genetic programs. While the MYB‐bHLH‐WD40 module is well studied in Arabidopsis, recent findings reveal that HD‐Zip IV transcription factors drive multicellular and glandular trichome development through dose‐dependent mechanisms.
Meng Li +3 more
wiley +1 more source
From Plant to Yeast—Advances in Biosynthesis of Artemisinin
Molecules, 2022 Malaria is a life-threatening disease. Artemisinin-based combination therapy (ACT) is the preferred choice for malaria treatment recommended by the World Health Organization.
Le Zhao +6 more
doaj +1 more source
Advanced Science, EarlyView.Genome‐scale metabolic modeling is preceded to the engineered E. coli cell factory for the de novo biosynthesis of biopesticide chrysanthemic acid. The debranching strategy redirects metabolic flux, enhancing precursor and target compound production.
Jiangpeng Yu +6 more
wiley +1 more source
Metabolic regulation and engineering of artemisinin biosynthesis in A. annua
Medicinal Plant Biology, 2023 Artemisinin is a potent anti-malarial sesquiterpene lactone that is naturally biosynthesized in glandular trichomes of a Chinese herbal plant, Artemisia annua. Although semi-synthesis of artemisinin in yeast has been feasible, at present the A.
Yueli Tang +4 more
doaj +1 more source
Artemisinin: From Chinese Herbal Medicine to Modern Chemotherapy [PDF]
, 2019 Malaria is a disease that has blighted humankind since early times. The first antimalarial treatment available to Europeans was the dried bark of the cinchona tree from Peru. The main problem in its use was adulteration by other material.
Butler, Anthony
core +1 more source
Automatic differential analysis of NMR experiments in complex samples
, 2017 Liquid state NMR is a powerful tool for the analysis of complex mixtures of unknown molecules. This capacity has been used in many analytical approaches: metabolomics, identification of active compounds in natural extracts, characterization of species ...
Bourjot, Mélanie +6 more
core +2 more sources
Health Worker Factors Associated with Prescribing of Artemisinin Combination Therapy for Uncomplicated Malaria in Rural Tanzania. [PDF]
, 2013 Improving malaria case management is partially dependent on health worker compliance with clinical guidelines. This study assessed health worker factors associated with correct anti-malarial prescribing practices at two sites in rural Tanzania.
Abdulla, Salim +7 more
core +4 more sources