Results 91 to 100 of about 30,074 (243)

High‐Dose Ascorbic Acid Combined With Dihydroartemisinin Inhibits Lung Adenocarcinoma Malignancy by Inducing Ferroptosis via SLC7A11/GPX4 Pathway

Journal of Cellular and Molecular Medicine, Volume 29, Issue 24, December 2025.
ABSTRACT This study evaluated the effect of ascorbic acid (AA) combined with dihydroartemisinin (DHA) in lung adenocarcinoma (LUAD) and the underlying mechanisms to determine whether this combination therapy provides a new therapeutic direction for the treatment of LUAD. The CCK‐8, colony formation and transwell assays were used to assess the vitality,
Lan Li, Fei Lu, Sisong Shu, Xiao Jiang, Han Lu, Ke Cao, Zhengting Chen, Jingyan Gao, Mengyuan Liu, Li Chang, Wenhui Li   +10 more
wiley   +1 more source

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source

A stratified random survey of the proportion of poor quality oral artesunate sold at medicine outlets in the Lao PDR – implications for therapeutic failure and drug resistance

Malaria Journal, 2009
Background Counterfeit oral artesunate has been a major public health problem in mainland SE Asia, impeding malaria control. A countrywide stratified random survey was performed to determine the availability and quality of oral artesunate in pharmacies ...
Vongsack Latsamy, Khounsaknalath Lamphet, Hostetler Dana, Mildenhall Dallas C, Nyadong Leonard, Hampton Christina Y, Insixiengmay Vongsavanh, Phommavong Khamlieng, Manolin Ot, Fernández Facundo M, Green Michael D, Sengaloundeth Sivong, Phompida Samlane, Vanisaveth Viengxay, Syhakhang Lamphone, Newton Paul N   +15 more
doaj   +1 more source

Evaluation of hematological changes in Plasmodium falciparum–infected patients before and after artesunate-mefloquine treatment in Dak Lak province, Vietnam [PDF]

, 2020
Quang Hong Huynh, Khanh Van Chau, Hien Thanh Pham, Hien Tinh Tran, Nhien Thuy Thanh Nguyen, Hong Duc Nguyen   +5 more
openalex   +1 more source

The five continuum of care criteria that should accompany rectal artesunate interventions: lessons learned from an implementation study in Malawi [PDF]

, 2023
Monique S. Oliff, Pamela Muniina, Kenneth Babigumira, John Phuka, Hans Rietveld, John Sande, Humphreys Nsona, Maud Majeres Lugand   +7 more
openalex   +1 more source

Costing Artemisinin-based Combination Therapy for Malaria in Tanzania [PDF]

, 2005
Malaria continues to be a major contributor to the burden of disease in Tanzania, with a prevalence of 33.39 percent nationally. As antimalarial resistance to sulfadoxine-pyrimethamine in Tanzania continues to grow, the government is in the process of ...
Derriennic, Yann, Wolf, Katherine
core  

Predicting the Disposition of the Antimalarial Drug Artesunate and its Active Metabolite Dihydroartemisinin Using Physiologically-Based Pharmacokinetic Modeling [PDF]

, 2020
Ryan Arey, Brad Reisfeld
openalex   +1 more source

Randomized controlled trial of artesunate or artemether in Vietnamese adults with severe falciparum malaria

Malaria Journal, 2010
Background Both artemether and artesunate have been shown to be superior to quinine for the treatment of severe falciparum malaria in Southeast Asian adults, although the magnitude of the superiority has been greater for artesunate than artemether. These
White Nicholas J, Chuong Ly V, Sinh Dinh X, Chau Tran TH, Mai Nguyen TH, Day Nicholas, Tuan Phung Q, Phu Nguyen H, Farrar Jeremy, Hien Tran T   +9 more
doaj   +1 more source

Safety and pharmacokinetic properties of a new formulation of parenteral artesunate in healthy Thai volunteers

Malaria Journal
Background Parenteral artesunate is the first-line therapy for severe malaria. Artesunate, in its current formulation, must be prepared immediately before administration by first dissolving in sodium bicarbonate solution and then diluting in saline.
Joel Tarning, Borimas Hanboonkunupakarn, Richard M. Hoglund, Kesinee Chotivanich, Mavuto Mukaka, Sasithon Pukrittayakamee, Nicholas P. J. Day, Nicholas J. White, Arjen M. Dondorp, Podjanee Jittamala   +9 more
doaj   +1 more source

In Vivo and In Vitro Taste Assessment of Artesunate-Mefloquine, Praziquantel, and Benznidazole Drugs for Neglected Tropical Diseases and Pediatric Patients

, 2021
Janine Boniatti, Raúl Marcelo, Rafaela Teixeira, Tamires de A V Gandos, Luis P. S. Rios, Izabelle A. M. Ferreira, Karina C. Oliveira, Sabrińa Calil-Eliás, Aíla Karla Mota Santana, Laís Bastos da Fonseca, Flávio M. Shimizu, Olívia Carr, Osvaldo N. Oliveira, Fábio Moysés Lins Dantas, Fábio Coelho Amendoeira, Alessandra Lifsitch Viçosa   +15 more
openalex   +1 more source