Adherence to artemether/lumefantrine treatment in children under real-life situations in rural Tanzania. [PDF]
, 2012 A follow-up study was conducted to determine the magnitude of and factors related to adherence to artemether/lumefantrine (ALu) treatment in rural settings in Tanzania.
Gustafsson, Lars L +6 more
core +2 more sources
Immune Modulation by Plasmodium yoelii: Insights From Lethal and Non‐Lethal Strains
Parasite Immunology, Volume 48, Issue 1, January 2026.ABSTRACT Malaria pathogenesis is driven by intricate host–parasite interactions that determine immune balance and clinical outcome. The Plasmodium yoelii model, particularly its lethal (17XL) and non‐lethal (17XNL) strains, provides a robust framework to investigate these dynamics.
Sharoen Yu Ming Lim
wiley +1 more source
Efficacy and Safety of Mefloquine, Artesunate, Mefloquine-Artesunate, and Praziquantel against Schistosoma haematobium: Randomized, Exploratory Open-Label Trial [PDF]
, 2017 Background. Morbidity control of schistosomiasis relies on a single drug, praziquantel. The antimalarial drug mefloquine possesses interesting antischistosomal properties, yet no clinical studies have been performed. Methods.
Adoubryn, Koffi D. +7 more
core
Saleability of Anti-malarials in Private Drug Shops in Muheza, Tanzania: A Baseline study in an era of assumed Artemisinin Ccombination Therapy (ACT). [PDF]
, 2011 Artemether-lumefantrine (ALu) replaced sulphadoxine-pymimethamine (SP) as the official first-line anti-malarial in Tanzania in November 2006. So far, artemisinin combination therapy (ACT) is contra-indicated during pregnancy by the national malaria ...
AM Rønn +26 more
core +4 more sources
The Effect of Artesunate on Bleomycin‑Induced Pulmonary Fibrosis
Acta Clinica CroaticaDespite new drug alternatives, no curative treatment for idiopathic pulmonary fibrosis (IPF) currently exists. This study aimed to evaluate the effects of artesunate on fibrosis, pulmonary hypertension, and inflammation-related changes in IPF.
Aysun Şengul +9 more
doaj +1 more source
Journal of Infection and Public Health, 2014 Summary: Severe malaria kills more than a half million people each year. Based on high-quality evidence of the efficacy superiority of artesunate over quinine in adults and children with severe malaria, the World Health Organization guidelines have been ...
Jean Jacques N. Noubiap
doaj +1 more source
Molecular Markers of Antimalarial Drug Resistance in Plasmodium falciparum From Kumasi, Ghana, 2023
Tropical Medicine &International Health, Volume 31, Issue 1, Page 43-48, January 2026.ABSTRACT Objectives Artemisinin partial resistance has emerged in East Africa and is feared to spread across the continent, potentially compromising artemisinin‐based combination treatment. Molecular markers can serve as early warning signals for the development of specific drug resistance.
Albert Dennis Kegya +10 more
wiley +1 more source
A reiterative method for calculating the early bactericidal activity of antituberculosis drugs.
, 2002 Studies of early bactericidal activity (EBA) are important in the rapid evaluation of new antituberculosis drugs. Historically, these have concentrated on the log fall in the viable count in sputum during the first 48 hours of therapy.
Charalambous, Bambos M +2 more
core +1 more source
, 2008 Buffet and colleagues have reviewed some of the potential benefits and drawbacks of intermittent preventive antimalarial treatment in children (IPTc).
Bojang, Kalifa +5 more
core +1 more source
A randomized open study to assess the efficacy and tolerability of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Cambodia. [PDF]
, 2007 OBJECTIVES: To compare the efficacy and tolerability of dihydroartemisinin-piperaquine (DHA-PQP) with that of a 3-day regimen of mefloquine and artesunate (MAS3) for the treatment of uncomplicated falciparum malaria in Cambodia.
Ashley +16 more
core +2 more sources