Results 11 to 20 of about 1,142 (172)

Neuroactive compounds obtained from arthropod venoms as new therapeutic platforms for the treatment of neurological disorders [PDF]

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2015
The impact of neurological disorders in society is growing with alarming estimations for an incidence increase in the next decades. These disorders are generally chronic and can affect individuals early during productive life, imposing real limitations ...
Victoria Monge-Fuentes   +8 more
doaj   +3 more sources

Peptide Toxin Diversity and a Novel Antimicrobial Peptide from the Spider Oxyopes forcipiformis [PDF]

open access: yesToxins
Spider venoms are emerging as a rich source of bioactive peptide toxins with therapeutic potential. Lynx spiders of the genus Oxyopes are small, cursorial hunters that employ complex venom to subdue arthropod prey.
Kexin Wang   +8 more
doaj   +3 more sources

Antimicrobial peptides from arthropod venoms exhibit activity against Sporothrix species [PDF]

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases
Background: Sporotrichosis is a fungal infection caused by species of the Sporothrix schenckii complex. Antifungal treatment with itraconazole and amphotericin B is limited by increasing resistance, adverse effects, and prolonged treatment courses ...
Maiara Campolina de Miranda   +7 more
doaj   +3 more sources

Spider venom peptides Ht1a and Gg1a are toxic to honeybee parasite Varroa destructor by topical application [PDF]

open access: yesnpj Drug Discovery
Global food supply strongly depends on honeybee pollination services, which are threatened by insecticides and pests such as parasitic Varroa destructor mites.
Volker Herzig   +14 more
doaj   +3 more sources

Arthropod venom Hyaluronidases: biochemical properties and potential applications in medicine and biotechnology

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2015
Hyaluronidases are enzymes that mainly degrade hyaluronan, the major glycosaminoglycan of the interstitial matrix. They are involved in several pathological and physiological activities including fertilization, wound healing, embryogenesis, angiogenesis,
Karla C F Bordon   +3 more
doaj   +2 more sources

Mast cells and IgE in defense against venoms: Possible “good side” of allergy?

open access: yesAllergology International, 2016
Physicians think of mast cells and IgE primarily in the context of allergic disorders, including fatal anaphylaxis. This ‘bad side’ of mast cells and IgE is so well accepted that it can be difficult to think of them in other contexts, particularly those ...
Stephen J. Galli   +3 more
doaj   +2 more sources

Improving the Annotation of the Venom Gland Transcriptome of Pamphobeteus verdolaga, Prospecting Novel Bioactive Peptides

open access: yesToxins, 2022
Spider venoms constitute a trove of novel peptides with biotechnological interest. Paucity of next-generation-sequencing (NGS) data generation has led to a description of less than 1% of these peptides. Increasing evidence supports the underestimation of
Cristian Salinas-Restrepo   +7 more
doaj   +2 more sources

Antimicrobial, Insecticidal and Cytotoxic Activity of Linear Venom Peptides from the Pseudoscorpion Chelifer cancroides

open access: yesToxins, 2022
Linear cationic venom peptides are antimicrobial peptides (AMPs) that exert their effects by damaging cell membranes. These peptides can be highly specific, and for some, a significant therapeutic value was proposed, in particular for treatment of ...
Jonas Krämer   +8 more
doaj   +2 more sources

Comparative Effects of Snake Envenomation on Rabbit Carcass Decomposition and Insect Succession in a Forensic Context [PDF]

open access: yesInsects
Background: Snake envenomation represents a significant health concern in some regions of the world, with fatal cases occasionally requiring forensic investigation to estimate the postmortem interval (PMI).
Abdelwahab Khalil   +6 more
doaj   +2 more sources

AaeAP1 and AaeAP2: Novel Antimicrobial Peptides from the Venom of the Scorpion, Androctonus aeneas: Structural Characterisation, Molecular Cloning of Biosynthetic Precursor-Encoding cDNAs and Engineering of Analogues with Enhanced Antimicrobial and Anticancer Activities

open access: yesToxins, 2015
The main functions of the abundant polypeptide toxins present in scorpion venoms are the debilitation of arthropod prey or defence against predators.
Qiang Du   +10 more
doaj   +2 more sources

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