Results 31 to 40 of about 41,853 (158)

Proteomic Investigations of Two Pakistani Naja Snake Venoms Species Unravel the Venom Complexity, Posttranslational Modifications, and Presence of Extracellular Vesicles

open access: yes, 2020
Latest advancement of omics technologies allows in-depth characterization of venom compositions. In the present work we present a proteomic study of two snake venoms of the genus Naja i.e., Naja naja (black cobra) and Naja oxiana (brown cobra) of ...
Zia Mughal   +8 more
core   +1 more source

Proteomic and Transcriptomic Techniques to Decipher the Molecular Evolution of Venoms

open access: yes, 2021
Nature’s library of venoms is a vast and untapped resource that has the potential of becoming the source of a wide variety of new drugs and therapeutics.
Reza Sharif-Naeini   +1 more
core   +1 more source

Size, Spines, and Nests: What Drives Variation in Death‐Feigning Behavior in Fungus‐Farming Ants?

open access: yesIntegrative Zoology, EarlyView.
We investigated death‐feigning (DF; thanatosis) in fungus‐farming ants, testing how stimulus intensity, morphology, and nest traits shape its occurrence and duration using generalized linear mixed models. Stronger stimuli increased both likelihood and duration, but most variation was structured across species, colonies, and individuals.
Danon Clemes Cardoso   +2 more
wiley   +1 more source

Snake Venoms in Drug Discovery: Valuable Therapeutic Tools for Life Saving

open access: yes, 2019
Animal venoms are used as defense mechanisms or to immobilize and digest prey. In fact, venoms are complex mixtures of enzymatic and non-enzymatic components with specific pathophysiological functions.
Tarek Mohamed Abd El-Aziz   +2 more
core   +1 more source

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

open access: yesAllergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz   +22 more
wiley   +1 more source

Parasitic wasp‐associated polydnavirus and venom affect arthropod community assembly on wild cabbage via the caterpillar host

open access: yesEcological Entomology, EarlyView.
Cotesia glomerata polydnavirus and venom, either alone or in combination, affect colonisation by members of the arthropod community in a natural field setting. Plants damaged by P. brassicae injected with both polydnavirus and venom were colonised more often by Mamestra brassicae caterpillars, Myzus persicae aphids and aphid parasitoids compared to ...
Sarah Naomi Kalisvaart   +5 more
wiley   +1 more source

Spider venom administration impairs glioblastoma growth and modulates immune response in a non-clinical model

open access: yesScientific Reports, 2020
Molecules from animal venoms are promising candidates for the development of new drugs. Previous in vitro studies have shown that the venom of the spider Phoneutria nigriventer (PnV) is a potential source of antineoplastic components with activity in ...
Amanda Pires Bonfanti   +12 more
doaj   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

open access: yesInsect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto   +2 more
wiley   +1 more source

Towards Therapeutic Applications of Arthropod Venom K+-Channel Blockers in CNS Neurologic Diseases Involving Memory Acquisition and Storage

open access: yesJournal of Toxicology, 2012
Potassium channels are the most heterogeneous and widely distributed group of ion channels and play important functions in all cells, in both normal and pathological mechanisms, including learning and memory processes.
Christiano D. C. Gati   +2 more
doaj   +1 more source

Integrative transcriptomic and machine learning approaches reveal candidate genes for silk and venom production in Bibionomorpha (Diptera)

open access: yesInsect Molecular Biology, EarlyView.
Multi‐species transcriptomics and deep learning identified candidate genes associated with silk and venom production in Bibionomorpha. Venom‐associated genes were enriched in proteases, inhibitors and pore‐forming proteins, whereas silk‐related genes showed chitin‐binding and peritrophin domains. Integrating co‐expression networks, machine learning and
Daniel Kenji Matuo   +2 more
wiley   +1 more source

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