Results 1 to 10 of about 447,945 (376)
Key roles of the superficial zone in articular cartilage physiology, pathology, and regeneration [PDF]
Chinese Medical Journal. The superficial zone (SFZ) of articular cartilage is an important interface that isolates deeper zones from the microenvironment of the articular cavity and is directly exposed to various biological and mechanical stimuli. The SFZ is not only a crucial
Li Guo +4 more
doaj +2 more sources
Ultramodern natural and synthetic polymer hydrogel scaffolds for articular cartilage repair and regeneration [PDF]
BioMedical Engineering OnLineArticular cartilage injury is a serious bone disease that can result in disabilities. With the rapid increase in the aging population, this disorder has become an increasingly important public health issue.
Chun-Sheng Li +8 more
doaj +2 more sources
Engineering gene-activated bioprinted scaffolds for enhancing articular cartilage repair [PDF]
Materials Today BioUntreated articular cartilage injuries often result in severe chronic pain and dyskinesia. Current repair strategies have limitations in effectively promoting articular cartilage repair, underscoring the need for innovative therapeutic approaches. A gene-
Min Wang +4 more
doaj +2 more sources
Mesenchymal Stem Cells for Treating Articular Cartilage Defects and Osteoarthritis
Cell Transplantation, 2015 Articular cartilage damage and osteoarthritis are the most common joint diseases. Joints are prone to damage caused by sports injuries or aging, and such damage regularly progresses to more serious joint disorders, including osteoarthritis, which is a ...
Yu Wang +4 more
doaj +2 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance Cartilage is essential in vertebrate development and adulthood. Cartilage growth plates ensure skeletal growth until closing at puberty, and articular cartilage ensures lifelong structural and functional integrity of joints.
A. Haseeb +10 more
semanticscholar +1 more source
Science Advances, 2021 A photocrosslinking hydrogel technique facilitates articular cartilage repair in minimally invasive surgery.
Yujie Hua +10 more
semanticscholar +1 more source
Mechanical stress determines the configuration of TGFβ activation in articular cartilage
Nature Communications, 2021 Our incomplete understanding of osteoarthritis (OA) pathogenesis has significantly hindered the development of disease-modifying therapy. The functional relationship between subchondral bone (SB) and articular cartilage (AC) is unclear.
G. Zhen +14 more
semanticscholar +1 more source
Strategies for Articular Cartilage Repair and Regeneration
Frontiers in Bioengineering and Biotechnology, 2021 Articular cartilage is an avascular tissue, with limited ability to repair and self-renew. Defects in articular cartilage can induce debilitating degenerative joint diseases such as osteoarthritis.
Yanxi Liu, Karan M. Shah, Jian Luo
semanticscholar +1 more source
Frontiers in Bioengineering and Biotechnology, 2023 Focal lesions of articular cartilage give rise to pain and reduced joint function and may, if left untreated, lead to osteoarthritis. Implantation of in vitro generated, scaffold-free autologous cartilage discs may represent the best treatment option ...
Nadine Frerker +9 more
doaj +1 more source
Vitrification of particulated articular cartilage via calculated protocols
npj Regenerative Medicine, 2021 Preserving viable articular cartilage is a promising approach to address the shortage of graft tissue and enable the clinical repair of articular cartilage defects in articulating joints, such as the knee, ankle, and hip.
Kezhou Wu +4 more
doaj +1 more source