Ultramodern natural and synthetic polymer hydrogel scaffolds for articular cartilage repair and regeneration. [PDF]
Articular cartilage injury is a serious bone disease that can result in disabilities. With the rapid increase in the aging population, this disorder has become an increasingly important public health issue.
Li CS+8 more
europepmc +2 more sources
CCN family member 2/connective tissue growth factor (CCN2/CTGF) has anti-aging effects that protect articular cartilage from age-related degenerative changes. [PDF]
To examine the role of connective tissue growth factor CCN2/CTGF (CCN2) in the maintenance of the articular cartilaginous phenotype, we analyzed knee joints from aging transgenic mice (TG) overexpressing CCN2 driven by the Col2a1 promoter.
Shinsuke Itoh+6 more
doaj +1 more source
The mechanical properties of biological tissues influence their function and can predict degenerative conditions before gross histological or physiological changes are detectable. This is especially true for structural tissues such as articular cartilage,
Katherine M. Arnold+3 more
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Hyaline articular cartilage lacks blood vessels, lymphatics, and nerves and is characterised by limited self-repair ability following injury. Traditional techniques of articular cartilage repair and regeneration all have certain limitations.
Shuangpeng Jiang+8 more
semanticscholar +1 more source
Engineering gene-activated bioprinted scaffolds for enhancing articular cartilage repair. [PDF]
Untreated articular cartilage injuries often result in severe chronic pain and dyskinesia. Current repair strategies have limitations in effectively promoting articular cartilage repair, underscoring the need for innovative therapeutic approaches. A gene-
Wang M, Wang J, Xu X, Li E, Xu P.
europepmc +2 more sources
Influence of collagen fibre orientation on the frictional properties of articular cartilage
Articular cartilage has a unique collagen fibre network structure that exhibits both anisotropy and depth dependency. Collagen fibre orientation in a cross‐section parallel to the articular cartilage surface may affect the lubrication properties of ...
Seido Yarimitsu+2 more
doaj +1 more source
During the development of the appendicular skeleton, the cartilaginous templates undergo hypertrophic differentiation and remodels into bone, except for the cartilage most adjacent to joint cavities where hypertrophic differentiation and endochondral ...
Michael Chau+9 more
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Electrically Conductive Hydrogels for Articular Cartilage Tissue Engineering
Articular cartilage is a highly specialized tissue found in diarthrodial joints, which is crucial for healthy articular motion. Despite its importance, articular cartilage has limited regenerative capacities, and the degeneration of this tissue is a ...
Filipe Miguel+3 more
doaj +1 more source
Use of mesenchymal stem cells seeded on the scaffold in articular cartilage repair
Articular cartilage has poor capacity for repair. Once damaged, they degenerate, causing functional impairment of joints. Allogeneic cartilage transplantation has been performed for functional recovery of articular cartilage.
Kaoru Yamagata+2 more
doaj +1 more source
The influences of walking, running and stair activity on knee articular cartilage: Quantitative MRI using T1 rho and T2 mapping. [PDF]
To explore the different influences of walking, running and stair activity on knee articular cartilage with T1 rho and T2 mapping sequences.MRI (3.0-T) scans of the right knee were performed in twenty-three young healthy adults immediately after 30 ...
Meng Chen+6 more
doaj +1 more source