Results 21 to 30 of about 176,243 (319)

Physiological incongruity of the humero-ulnar joint [PDF]

open access: yes, 1993
Investigations into the distribution of subchondral bone density in the human elbow have suggested that the geometry of the trochlear notch deviates from a perfect fit with the trochlea, and that the load is transmitted ventrally and dorsally rather than
Eckstein, Felix   +5 more
core   +1 more source

Repair of full-thickness articular cartilage defects using IEIK13 self-assembling peptide hydrogel in a non-human primate model

open access: yesScientific Reports, 2021
Articular cartilage is built by chondrocytes which become less active with age. This declining function of the chondrocytes, together with the avascular nature of the cartilage, impedes the spontaneous healing of chondral injuries.
Alexandre Dufour   +10 more
doaj   +1 more source

Restoration of the extracellular matrix in human osteoarthritic articular cartilage by overexpression of the transcription factor SOX9 [PDF]

open access: yes, 2007
Objective. Human osteoarthritis (OA) is characterized by a pathologic shift in articular cartilage homeostasis toward the progressive loss of extracellular matrix (ECM).
Cucchiarini, Magali   +5 more
core   +2 more sources

Cell sources for articular cartilage repair strategies: shifting from mono-cultures to co-cultures [PDF]

open access: yes, 2013
The repair of articular cartilage is challenging due to the sparse native cell population combined with the avascular and aneural nature of the tissue. In recent years cartilage tissue engineering has shown great promise.
Blitterswijk, C.A. van   +4 more
core   +3 more sources

Application of an acoustofluidic perfusion bioreactor for cartilage tissue engineering [PDF]

open access: yes, 2014
Cartilage grafts generated using conventional static tissue engineering strategies are characterised by low cell viability, suboptimal hyaline cartilage formation and, critically, inferior mechanical competency, which limit their application for ...
Li, Siwei   +7 more
core   +6 more sources

Differential gene expression associated with postnatal equine articular cartilage maturation

open access: yesBMC Musculoskeletal Disorders, 2008
Background Articular cartilage undergoes an important maturation process from neonate to adult that is reflected by alterations in matrix protein organization and increased heterogeneity of chondrocyte morphology.
Stromberg Arnold J   +3 more
doaj   +1 more source

A review of the differences between normal and osteoarthritis articular cartilage in human knee and ankle joints [PDF]

open access: yes, 2009
Background: Osteoarthritis (OA) is the most common joint disease yet its pathophysiology is still poorly understood. It is more prevalent in some lower limb joints than others; in particular the knee is more commonly affected than the ankle.
Beeson, Paul   +2 more
core   +1 more source

Patterns of Articular Cartilage Thickness in Pediatric and Adolescent Knees: A Magnetic Resonance Imaging–Based Study

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, 2021
Purpose: To establish normative values for articular cartilage thickness in pediatric and adolescent knees using magnetic resonance imaging (MRI) and investigate for any associations with age and skeletal maturity.
Sreetha Sidharthan, M.D.   +6 more
doaj   +1 more source

Treatment of Joint Cartilage Lesions with Cell Therapy [PDF]

open access: yes, 2008
Monográfico Osteoartritis[Resumen] Las lesiones del cartílago articular que no afectan a la integridad del hueso subcondral no se reparan espontáneamente.
Arufe, M.C.   +5 more
core   +2 more sources

Conditional knockdown of hyaluronidase 2 in articular cartilage stimulates osteoarthritic progression in a mice model

open access: yesScientific Reports, 2017
The catabolism of hyaluronan in articular cartilage remains unclear. The aims of this study were to investigate the effects of hyaluronidase 2 (Hyal2) knockdown in articular cartilage on the development of osteoarthritis (OA) using genetic manipulated ...
Yoshitoshi Higuchi   +10 more
doaj   +1 more source

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