Results 21 to 30 of about 176,243 (319)
Physiological incongruity of the humero-ulnar joint [PDF]
Investigations into the distribution of subchondral bone density in the human elbow have suggested that the geometry of the trochlear notch deviates from a perfect fit with the trochlea, and that the load is transmitted ventrally and dorsally rather than
Eckstein, Felix +5 more
core +1 more source
Articular cartilage is built by chondrocytes which become less active with age. This declining function of the chondrocytes, together with the avascular nature of the cartilage, impedes the spontaneous healing of chondral injuries.
Alexandre Dufour +10 more
doaj +1 more source
Restoration of the extracellular matrix in human osteoarthritic articular cartilage by overexpression of the transcription factor SOX9 [PDF]
Objective. Human osteoarthritis (OA) is characterized by a pathologic shift in articular cartilage homeostasis toward the progressive loss of extracellular matrix (ECM).
Cucchiarini, Magali +5 more
core +2 more sources
Cell sources for articular cartilage repair strategies: shifting from mono-cultures to co-cultures [PDF]
The repair of articular cartilage is challenging due to the sparse native cell population combined with the avascular and aneural nature of the tissue. In recent years cartilage tissue engineering has shown great promise.
Blitterswijk, C.A. van +4 more
core +3 more sources
Application of an acoustofluidic perfusion bioreactor for cartilage tissue engineering [PDF]
Cartilage grafts generated using conventional static tissue engineering strategies are characterised by low cell viability, suboptimal hyaline cartilage formation and, critically, inferior mechanical competency, which limit their application for ...
Li, Siwei +7 more
core +6 more sources
Differential gene expression associated with postnatal equine articular cartilage maturation
Background Articular cartilage undergoes an important maturation process from neonate to adult that is reflected by alterations in matrix protein organization and increased heterogeneity of chondrocyte morphology.
Stromberg Arnold J +3 more
doaj +1 more source
A review of the differences between normal and osteoarthritis articular cartilage in human knee and ankle joints [PDF]
Background: Osteoarthritis (OA) is the most common joint disease yet its pathophysiology is still poorly understood. It is more prevalent in some lower limb joints than others; in particular the knee is more commonly affected than the ankle.
Beeson, Paul +2 more
core +1 more source
Purpose: To establish normative values for articular cartilage thickness in pediatric and adolescent knees using magnetic resonance imaging (MRI) and investigate for any associations with age and skeletal maturity.
Sreetha Sidharthan, M.D. +6 more
doaj +1 more source
Treatment of Joint Cartilage Lesions with Cell Therapy [PDF]
Monográfico Osteoartritis[Resumen] Las lesiones del cartílago articular que no afectan a la integridad del hueso subcondral no se reparan espontáneamente.
Arufe, M.C. +5 more
core +2 more sources
The catabolism of hyaluronan in articular cartilage remains unclear. The aims of this study were to investigate the effects of hyaluronidase 2 (Hyal2) knockdown in articular cartilage on the development of osteoarthritis (OA) using genetic manipulated ...
Yoshitoshi Higuchi +10 more
doaj +1 more source

