Results 31 to 40 of about 176,243 (319)
Direct Visualisation of the Depth-Dependent Mechanical Properties of Full-Thickness Articular Cartilage. [PDF]
, 2012 The structural anisotropy of articular cartilage controls its deformation response. As proteoglycans and collagen vary with depth, simple uniaxial compression results in inhomogeneous deformation with distinct depth-dependent mechanical properties ...
Szarko, M, Xia, Y
core +1 more source
Gels, 2021 Joint diseases that mainly lead to articular cartilage injury with prolonged severe pain as well as dysfunction have remained unexplained for many years.
Xu Han +4 more
doaj +1 more source
In vitro and in vivo validation of human and goat chondrocyte labeling by green fluorescent protein lentivirus transduction [PDF]
, 2010 We investigated whether human articular chondrocytes can be labeled efficiently and for long-term with a green fluorescent protein (GFP) lentivirus and whether the viral transduction would influence cell proliferation and tissue-forming capacity.
Acharya, Chitrangada +9 more
core +1 more source
Bioactive Materials, 2023 Lacking self-repair abilities, injuries to articular cartilage can lead to cartilage degeneration and ultimately result in osteoarthritis. Tissue engineering based on functional bioactive scaffolds are emerging as promising approaches for articular ...
Yucong Li +15 more
doaj +1 more source
24R,25-Dihydroxyvitamin D3 Protects against Articular Cartilage Damage following Anterior Cruciate Ligament Transection in Male Rats [PDF]
, 2016 Osteoarthritis (OA) in humans is associated with low circulating 25-hydroxyvitamin D3 [25 (OH)D3]. In vitamin D replete rats, radiolabeled 24R,25-dihydroxyvitamin D3 [24R,25 (OH)2D3] accumulates in articular cartilage following injection of [3 H]-25(OH ...
Boyan, Barbara D. +6 more
core +4 more sources
Key roles of the superficial zone in articular cartilage physiology, pathology, and regeneration
Chinese Medical Journal. The superficial zone (SFZ) of articular cartilage is an important interface that isolates deeper zones from the microenvironment of the articular cavity and is directly exposed to various biological and mechanical stimuli. The SFZ is not only a crucial
Li Guo +4 more
doaj +1 more source
Bone Research, 2022 Runt-related transcription factor 1 (Runx1) plays a key role in cartilage formation, but its function in articular cartilage formation is unclear. We generated non-inducible and inducible Runx1-deficient mice (Runx1 f/f Col2α1-Cre and Runx1 f/f Col2α1 ...
Yan Zhang +5 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2023 Objectives: This study aimed to investigate the morphological and mechanical changes in articular cartilage and subchondral bone during spontaneous hip osteoarthritis in guinea pigs.Materials and methods: Hip joints of guinea pigs were investigated at 1,
Jiazi Gao, Pengling Ren, He Gong
doaj +1 more source
Osteoarthritis severely decreases the elasticity and hardness of knee joint cartilage: A nanoindentation study [PDF]
, 2019 The nanoindentation method was applied to determine the elastic modulus and hardness of knee articular cartilage. Cartilage samples from both high weight bearing (HWB) and low weight bearing (LWB) femoral condyles were collected from patients diagnosed ...
Giersig, Michael +4 more
core +1 more source
Arthritis Care &Research, Accepted Article.Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy +9 more
wiley +1 more source