Results 41 to 50 of about 447,945 (376)
Bone Research, 2022 Runt-related transcription factor 1 (Runx1) plays a key role in cartilage formation, but its function in articular cartilage formation is unclear. We generated non-inducible and inducible Runx1-deficient mice (Runx1 f/f Col2α1-Cre and Runx1 f/f Col2α1 ...
Yan Zhang +5 more
doaj +1 more source
Treatment of Joint Cartilage Lesions with Cell Therapy [PDF]
, 2008 Monográfico Osteoartritis[Resumen] Las lesiones del cartílago articular que no afectan a la integridad del hueso subcondral no se reparan espontáneamente.
Arufe, M.C. +5 more
core +2 more sources
Repair of Damaged Articular Cartilage: Current Approaches and Future Directions
International Journal of Molecular Sciences, 2018 Articular hyaline cartilage is extensively hydrated, but it is neither innervated nor vascularized, and its low cell density allows only extremely limited self-renewal.
E. V. Medvedeva +6 more
semanticscholar +1 more source
In vitro and in vivo validation of human and goat chondrocyte labeling by green fluorescent protein lentivirus transduction [PDF]
, 2010 We investigated whether human articular chondrocytes can be labeled efficiently and for long-term with a green fluorescent protein (GFP) lentivirus and whether the viral transduction would influence cell proliferation and tissue-forming capacity.
Acharya, Chitrangada +9 more
core +1 more source
Scientific Reports, 2017 The catabolism of hyaluronan in articular cartilage remains unclear. The aims of this study were to investigate the effects of hyaluronidase 2 (Hyal2) knockdown in articular cartilage on the development of osteoarthritis (OA) using genetic manipulated ...
Yoshitoshi Higuchi +10 more
doaj +1 more source
Gels, 2021 Joint diseases that mainly lead to articular cartilage injury with prolonged severe pain as well as dysfunction have remained unexplained for many years.
Xu Han +4 more
doaj +1 more source
Three-Dimensional Bioprinting of Articular Cartilage: A Systematic Review
Cartilage, 2018 Objective Treatment of chondral injury is clinically challenging. Available chondral repair/regeneration techniques have significant shortcomings. A viable and durable tissue engineering strategy for articular cartilage repair remains an unmet need.
Yang Wu +5 more
semanticscholar +1 more source
Frontiers in Bioengineering and Biotechnology, 2023 Objectives: This study aimed to investigate the morphological and mechanical changes in articular cartilage and subchondral bone during spontaneous hip osteoarthritis in guinea pigs.Materials and methods: Hip joints of guinea pigs were investigated at 1,
Jiazi Gao, Pengling Ren, He Gong
doaj +1 more source
Materials Today Bio, 2022 Functional repair of articular cartilage defects is always a great challenge in joint surgery clinically. Tissue engineering strategies that combine autologous cell implantation with three-dimensional scaffolds have proven effective for repairing ...
Litao Jia +7 more
doaj
Research progress of self-assembling peptide hydrogels in repairing cartilage defects
Frontiers in Materials, 2022 Due to the lack of blood vessels, nerves and lymphatic vessels, the capacity of articular cartilage to heal is extremely limited. Once damaged, it is urgent for articular cartilage to repair the injury.
Renyi Wang +8 more
doaj +1 more source