Results 41 to 50 of about 173,109 (331)

Runx1 is a key regulator of articular cartilage homeostasis by orchestrating YAP, TGFβ, and Wnt signaling in articular cartilage formation and osteoarthritis

Bone Research, 2022
Runt-related transcription factor 1 (Runx1) plays a key role in cartilage formation, but its function in articular cartilage formation is unclear. We generated non-inducible and inducible Runx1-deficient mice (Runx1 f/f Col2α1-Cre and Runx1 f/f Col2α1 ...
Yan Zhang, Tao Zuo, Abigail McVicar, Hui-Lin Yang, Yi-Ping Li, Wei Chen   +5 more
doaj   +1 more source

O-alg-THAM/gel hydrogels functionalized with engineered microspheres based on mesenchymal stem cell secretion recruit endogenous stem cells for cartilage repair

Bioactive Materials, 2023
Lacking self-repair abilities, injuries to articular cartilage can lead to cartilage degeneration and ultimately result in osteoarthritis. Tissue engineering based on functional bioactive scaffolds are emerging as promising approaches for articular ...
Yucong Li, Linlong Li, Ming Wang, Boguang Yang, Baozhen Huang, Shanshan Bai, Xiaoting Zhang, Nan Hou, Haixing Wang, Zhengmeng Yang, Chong Tang, Ye Li, Wayne Yuk-Wai Lee, Lu Feng, Micky D. Tortorella, Gang Li   +15 more
doaj   +1 more source

In vitro and in vivo validation of human and goat chondrocyte labeling by green fluorescent protein lentivirus transduction [PDF]

, 2010
We investigated whether human articular chondrocytes can be labeled efficiently and for long-term with a green fluorescent protein (GFP) lentivirus and whether the viral transduction would influence cell proliferation and tissue-forming capacity.
Acharya, Chitrangada, Barbero, Andrea, Candrian, Christian, Gianni-Barrera, Roberto, Jaquiery, Claude, Juelke, Henriette, Mainil-Varlet, Pierre, Martin, Ivan, Miot, Sylvie, Pelttari, Karoliina   +9 more
core   +1 more source

Conference on Articular Cartilage [PDF]

Annals of the Rheumatic Diseases, 1975
Introduction I. Structure of articular cartilage Microscopical appearance and organization of articular cartilage surfaces Scanning electron microscope study of normal human articular cartilage Sequential changes in superficial defects in articular cartilage studied with the scanning electron microscope Cartilage fibrillation versus ink-staining ...
Alice Maroudas, B. Weightman, G. E. Kempson   +2 more
openaire   +2 more sources

Key roles of the superficial zone in articular cartilage physiology, pathology, and regeneration

Chinese Medical Journal
. The superficial zone (SFZ) of articular cartilage is an important interface that isolates deeper zones from the microenvironment of the articular cavity and is directly exposed to various biological and mechanical stimuli. The SFZ is not only a crucial
Li Guo, Pengcui Li, Xueqin Rong, Xiaochun Wei, Xiangxiang Pan   +4 more
doaj   +1 more source

Intra-Articular Injections of Polyphenols Protect Articular Cartilage from Inflammation-Induced Degradation: Suggesting a Potential Role in Cartilage Therapeutics.

PLoS ONE, 2015
Arthritic diseases, such as osteoarthritis and rheumatoid arthritis, inflict an enormous health care burden on society. Osteoarthritis, a degenerative joint disease with high prevalence among older people, and rheumatoid arthritis, an autoimmune ...
Venkatachalam Natarajan, Balaraman Madhan, Moti L Tiku   +2 more
doaj   +1 more source

Effects of low tangential permeability in the superficial layer on the frictional property of articular cartilage

Biosurface and Biotribology, 2015
The biphasic characteristics of articular cartilage are known to play important roles in cartilage lubrication. However, it is still difficult to biotribologically explain the extremely low friction coefficient observed in articular cartilage.
H. Fujie, K. Imade
doaj   +1 more source

Correlation of Biomechanical Alterations under Gonarthritis between Overlying Menisci and Articular Cartilage

Applied Sciences, 2020
Just like menisci, articular cartilage is exposed to constant and varying stresses. Injuries to the meniscus are associated with the development of gonarthritis.
Johannes Pordzik, Anke Bernstein, Julius Watrinet, Hermann O. Mayr, Sergio H. Latorre, Hagen Schmal, Michael Seidenstuecker   +6 more
doaj   +1 more source

Gene expression profiling reveals similarities between the spatial architectures of postnatal articular and growth plate cartilage. [PDF]

PLoS ONE, 2014
Articular and growth plate cartilage are discrete tissues but arise from a common cartilaginous condensation and have comparable spatial architectures consisting of distinct layers of chondrocytes.
Michael Chau, Julian C Lui, Ellie B M Landman, Stephan-Stanislaw Späth, Andrea Vortkamp, Jeffrey Baron, Ola Nilsson   +6 more
doaj   +1 more source

Physician Referral Patterns to Physical Therapists for Managing Knee Osteoarthritis: A Retrospective Analysis of Electronic Health Records from an Integrated Health System

Arthritis Care &Research, Accepted Article.
Objectives This study aims to describe the frequency and timing of physician referrals to physical therapists (PT) and other treatments prescribed over 12 months in patients with recent onset of knee osteoarthritis (KOA). The study also aims to identify determinants of early PT referrals.
Samannaaz S. Khoja, Joel M. Stevans, Gustavo J. Almeida, Clair Smith, Janet K. Freburger   +4 more
wiley   +1 more source