Results 61 to 70 of about 441,477 (379)
Physiological incongruity of the humero-ulnar joint [PDF]
, 1993 Investigations into the distribution of subchondral bone density in the human elbow have suggested that the geometry of the trochlear notch deviates from a perfect fit with the trochlea, and that the load is transmitted ventrally and dorsally rather than
Eckstein, Felix +5 more
core +1 more source
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
Computational Models of Articular Cartilage [PDF]
Computational and Mathematical Methods in Medicine, 2013 In osteoarthritis, articular cartilage degenerates and eventually wears out, resulting in pain and disability. It is a major challenge in health care to prevent osteoarthritis or slow down the progression of the disease. The onset of osteoarthritis may result from an altered stress and strain state in cartilage, for example, due to an injury of ...
Rami K. Korhonen +3 more
openaire +3 more sources
Advanced Functional Materials, EarlyView.Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana +2 more
wiley +1 more source
Gene therapy for articular cartilage repair [PDF]
, 2007 Articular cartilage serves as the gliding surface of joints. It is susceptible to damage from trauma and from degenerative diseases. Restoration of damaged articular cartilage may be achievable through the use of cell-regulatory molecules that augment ...
Goater J. +8 more
core +2 more sources
Advanced Functional Materials, EarlyView.A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song +8 more
wiley +1 more source
Applied Sciences, 2020 Just like menisci, articular cartilage is exposed to constant and varying stresses. Injuries to the meniscus are associated with the development of gonarthritis.
Johannes Pordzik +6 more
doaj +1 more source
Cartilaginous Organoids: Advances, Applications, and Perspectives
Advanced NanoBiomed Research, 2023 Cartilage is a nonvascular and non‐neural, mesoderm‐derived tissue. Cartilage repair, especially articular cartilage repair and reconstruction, has always been a difficult problem in bone tissue engineering.
Yuhao Yu +4 more
doaj +1 more source
Scientific Reports, 2016 The in vivo measurement of articular cartilage deformation is essential to understand how mechanical forces distribute throughout the healthy tissue and change over time in the pathologic joint.
D. Chan +5 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia +7 more
wiley +1 more source