Results 191 to 200 of about 36,412 (300)

Therapeutic Potential of Irpex lacteus Polysaccharides in Lupus Nephritis: Insights From Gut Microbiota and Metabolomics Analysis in MRL/Lpr Mice

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
Polysaccharides from Irpex lacteus alleviated kidney inflammatory response. PCP could reverse the phenotype of MRL/lpr mice, reduce autoantibody levels, alleviate inflammatory responses, and improve renal function. Improving the body's metabolism by gut microbes may be the possible mechanism of PCP in treating LN.
Guoxin Ji   +9 more
wiley   +1 more source

Plant‐Based Food Preferences Rich in Polyphenols and Their Causal Effects on Inflammatory Bowel Disease

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
This Mendelian randomization study investigated causal relationships between polyphenol‐rich plant food preferences and inflammatory bowel disease (IBD) risk using genome‐wide association study data. Six dietary preferences were significantly associated with IBD risk.
Tinghui Yue   +6 more
wiley   +1 more source

Spirocyclic Diamine Scaffolds for Medicinal Chemistry

open access: yesHelvetica Chimica Acta, Volume 109, Issue 1, January 2026.
Here we enumerated 391 spirocyclic diamine drug scaffolds with ring sizes four to eight and found that most of them are unknown. We prepared four novel such spirocycles and discovered a micromolar inhibitor of the M4 muscarinic receptor. ABSTRACT Medicinal chemistry requires the exploration of structurally diverse compound families to expand the ...
Aline Carrel   +3 more
wiley   +1 more source

Aryl hydrocarbon receptor restrains tonic cytokine responses by inhibiting microbiota sensing in monocytes. [PDF]

open access: yesJ Clin Invest
Cros A   +13 more
europepmc   +1 more source

DNA Methylation of the Aryl Hydrocarbon Receptor Repressor Associations With Cigarette Smoking and Subclinical Atherosclerosis [PDF]

open access: bronze, 2015
Lindsay M. Reynolds   +27 more
openalex   +1 more source

An Integrated Engineering Approach to Creating Health‐Modulating Postbiotics

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 1, January 2026.
Postbiotics have emerged as a promising alternative to live probiotics, offering comparable health benefits while overcoming challenges related to safety, stability, and shelf life. The review addresses current challenges in standardizing postbiotic definitions and production processes, and by outlining future research directions necessary to unlock ...
Michael Leonidas Chikindas   +10 more
wiley   +1 more source

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