Results 131 to 140 of about 1,983,941 (246)

Aryl hydrocarbon receptor (AhR) inducers and estrogen receptor (ER) activities in surface sediments of Three Gorges Reservoir, China evaluated with in vitro cell bioassays

, 2014
Two types of biological tests were employed for monitoring the toxicological profile of sediment cores in the Three Gorges Reservoir (TGR), China. In the present study, sediments collected in June 2010 from TGR were analyzed for estrogen receptor (ER ...
Wang, Jingxian, Bovee, Toine F. H., Schramm, Karl-Werner, Bernhoeft, Silke, Wang, JX (reprint author), Tech Univ Munich, Ctr Life & Food Sci Land Use & Environm, Dept Biosci, Weihenstephaner Steig 23, D-85350 Freising Weihenstephan, Germany., Bi, Yonghong   +5 more
core   +1 more source

Aryl hydrocarbon receptor (AHR) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, Volume 46, Issue 12, Page 4264-4287, December 2026.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

Aryl hydrocarbon receptor (AHR) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

AHR2 as a Potential Integrator of Eco‐Evo‐Devo in Non‐Mammalian Vertebrates: A Focus on Fishes

Evolution &Development, Volume 28, Issue 4, December 2026.
AHR2 mediated signals in eco‐evo‐devo context: Left: Ontogenetic window illustrating how chemical ligands (green) interact with developmental responses (blue) through AHR2 signaling mechanisms (pink). Right: Evolutionary window illustrating how sequence and regulatory evolution of the AHR2 pathway can promote the emergence of novel phenotypes and ...
Leandro Lofeu, Christian Sturmbauer, Ehsan Pashay Ahi   +2 more
wiley   +1 more source

Analysis of the interaction between the co-chaperone p23 and the aryl hydrocarbon receptor

, 2015
The aryl hydrocarbon receptor (AhR) carboxyl terminal transcriptional activation domain was cloned, purified in denatured conditions from bacteria, refolded via limited dialysis, and analyzed for proper refolding via co-immunoprecipitation with the known
Thompson, John D.
core  

Aryl Hydrocarbon Receptor Is Dispensable for the Early Transcriptional Response of Mouse Macrophages to Type I Interferon

The FASEB Journal, Volume 40, Issue 22, 30 November 2026.
ABSTRACT Type I interferon (IFN‐I) signaling is essential in the homeostasis and activation of immune cells, and macrophages play a central role in the IFN‐I system. Dysregulation leads to tissue damage and autoimmunity, and IFN‐I signaling needs to be tightly fine‐tuned.
Darawan Tabtim‐On, Elodie Segura
wiley   +1 more source

Aryl hydrocarbon receptor and colitis

, 2013
The aryl hydrocarbon receptor (AhR), a transcription factor activated by a large variety of natural and synthetic ligands, has recently become the object of great interest among researchers since it represents an important link between environment and ...
PALLONE, FRANCESCO, Monteleone, I, MONTELEONE, GIOVANNI, Monteleone, G, MONTELEONE, IVAN, Pallone, F   +5 more
core   +1 more source

Macrophage PARP7 Alleviates Septic Cardiomyopathy by Interacting With TBK1 and Suppressing TBK1‐Driven Inflammatory Response

Advanced Science, Volume 13, Issue 63, 12 November 2026.
In septic cardiomyopathy, PARP7 directly binds TBK1 and mediates its ADP‐ribosylation, thereby repressing TBK1‐driven proinflammatory signaling in macrophages. ABSTRACT Septic cardiomyopathy is a life‐threatening complication of sepsis, and an uncontrolled inflammatory response represents a key pathogenic mechanism. PARP7 negatively regulates the IFN‐I
Jibo Han, Lintao Wang, Xin Zhong, Shenggang Zhao, Huihui Xie, Xue Han, Liming Lin, Yiting Lyu, Ke Xu, Jiajun Xu, Xiaowen Shi   +10 more
wiley   +1 more source

The aryl hydrocarbon receptor, CIITA and HLA-II: who is watching the watchdog?

Journal of Experimental & Clinical Cancer Research
Background A recent paper by Jin et al. reveals an unexpected role of the Aryl Hydrocarbon Receptor (AHR), so far considered an environmental sensor. The authors demonstrate that AHR transactivates CIITA, thereby up-regulating antigen-presenting HLA-II ...
Doriana Fruci, Patrizio Giacomini
doaj   +1 more source