Results 131 to 140 of about 44,282 (308)

Wildfires and Atopic Diseases: A Review

Allergy, EarlyView.
ABSTRACT Wildfire smoke is a major environmental health threat that has increased in frequency and severity in recent years. A hazardous component of wildfire smoke is particulate matter ≤ 2.5 μm (PM2.5). There is evidence to suggest that exposure to wildfire PM2.5 may increase the risk of developing or exacerbating atopic diseases, such as asthma ...
Alex Ha, John R. Balmes, Maria L. Wei
wiley   +1 more source

Molecular and Functional Properties of the Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a. [PDF]

Environ Sci Technol, 2020
Aranguren-Abadía L, Lille-Langøy R, Madsen AK, Karchner SI, Franks DG, Yadetie F, Hahn ME, Goksøyr A, Karlsen OA.   +8 more
europepmc   +1 more source

EAACI Guidelines on the Importance of Green Space in Urban Environments for Allergy and Asthma Prevention

Allergy, EarlyView.
ABSTRACT The allergy and asthma epidemic in urban societies following World War II is mostly caused by changes in the environment, diet and lifestyle. Disconnection of urban populations from the wider environment has reduced the protective factors building up immunological resilience.
Tari Haahtela, Liam O'Mahony, Claudia Traidl‐Hoffmann, Mubeccel Akdis, Ozlem Ceylan, Panagiotis Chaslaridis, Athanasios Damialis, Stefano Del Giacco, Antti Lauerma, Kari C. Nadeau, Inês Paciência, Isabella Pali‐Schöll, Oscar Palomares, Harald Renz, Jurgen Schwarze, Marilyn Urrutia‐Pereira, Carina Venter, Donata Vercelli, Tonya Winders, Cezmi A. Akdis, Marek Jutel, Ioana Agache   +21 more
wiley   +1 more source

Sinomenine induces the generation of intestinal Treg cells and attenuates arthritis via activation of aryl hydrocarbon receptor [PDF]

, 2016
Bei Tong, Xusheng Yuan, Yannong Dou, Xin Wu, Yuhui Wang, Yufeng Xia, Yue Dai   +6 more
openalex   +1 more source

Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side

Allergy, EarlyView.
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm, Mohammed Zghaebi, Bita Hambrecht, Tanja Kalic, Christopher C. Udoye, Rudolf Manz, Barbara Bohle, Katarzyna M. Sitnik, Julia Eckl‐Dorna, Heimo Breiteneder   +9 more
wiley   +1 more source

Offspring DNA methylation of the aryl-hydrocarbon receptor repressor gene is associated with maternal BMI, gestational age, and birth weight [PDF]

, 2015
Heather H. Burris, Andrea Baccarelli, Hyang‐Min Byun, Alejandra Cantoral, Allan C. Just, Ivan Pantic, Maritsa Solano-González, Katherine Svensson, Marcela Tamayo‐Ortiz, Yan Zhao, Robert O. Wright, Martha María Téllez‐Rojo   +11 more
openalex   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

Cytochrome P450 1A1 influences obesity‐induced pulmonary hypertension

British Journal of Pharmacology, EarlyView.
Background and Purpose The contribution of obesity to pulmonary arterial hypertension (PAH) pathophysiology remains poorly understood. Adipose tissue synthesises estrogens via cytochrome P450 (CYP) 19A1 (aromatase), whereas circulating estrogens are metabolised in the lung by CYP1A1.
Joshua P. Dignam, Smriti Sharma, Gregor Aitchison, Ayman Gebril, Ioannis Stasinopoulos, Sofia Laforest, Chelbi Coyle, Ruth Andrew, Natalie Z. M. Homer, Sébastien Bonnet, Sandra Breuils‐Bonnet, Martin Wabitsch, Margaret R. MacLean   +12 more
wiley   +1 more source

Decision letter: The aryl hydrocarbon receptor and interferon gamma generate antiviral states via transcriptional repression

, 2018
Bryan R. Cullen
openalex   +1 more source

The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation [PDF]

, 2013
Brenden W. Smith, Sarah S. Rozelle, Amy Leung, Jessalyn M. Ubellacker, Ashley Parks, Shirley Nah, Deborah L. French, Paul Gadue, Stefano Monti, David H.K. Chui, Martin H. Steinberg, Andrew L. Frelinger, Alan D. Michelson, Roger Théberge, Mark E. McComb, Catherine E. Costello, Darrell N. Kotton, Gustavo Mostoslavsky, David H. Sherr, George J. Murphy   +19 more
openalex   +1 more source