Results 41 to 50 of about 17,361 (234)

Arylamine N-acetyltransferase and arylalkylamine N-acetyltransferase in the mammalian pineal gland.

Journal of Biological Chemistry, 1984
Amine N-acetylation in the pineal gland is of special importance because it is the first step in the synthesis of melatonin from serotonin. In the present study the N-acetylation of arylamines and arylalkylamines by homogenates of rat and sheep pineal glands was investigated.
Pierre Voisin, M.A.A. Namboodiri, David C. Klein   +2 more
openalex   +3 more sources

Genetic and small molecule inhibition of arylamine N-acetyltransferase 1 reduces anchorage-independent growth in human breast cancer cell line MDA-MB-231. [PDF]

Mol Carcinog, 2018
Stepp MW, Doll MA, Carlisle SM, States JC, Hein DW.   +4 more
europepmc   +2 more sources

Summary of case study lecture at Biophysics and Structural Biology at Synchrotrons Workshop Triumph over Adversity: structure of arylamine N-acetyltransferase from M. tuberculosis. [PDF]

Biophys Rev, 2019
Garman EF.
europepmc   +3 more sources

Arylamine N-Acetyltransferase 2 [PDF]

, 2020
National Cancer Institute
openalex   +2 more sources

Arylamine N-acetyltransferase 2 Polymorphisms and the Risk of Endometriosis. [PDF]

Avicenna J Med Biotechnol, 2018
Barra F, Desideri LF, Scala C, Ferrero S.   +3 more
europepmc   +3 more sources

Human N-Acetyltransferase 1 and 2 Differ in Affinity Towards Acetyl-Coenzyme A Cofactor and N-Hydroxy-Arylamine Carcinogens

Frontiers in Pharmacology, 2022
Arylamine N-acetyltransferases catalyze the transfer of acetyl groups from the endogenous cofactor acetyl coenzyme A (AcCoA) to arylamine (N-acetylation) and N-hydroxy-arylamine (O-acetylation) acceptors.
David W. Hein, Mark A. Doll, Mariam R. Habil   +2 more
doaj   +1 more source

Arylamine N-Acetyltransferases in Mycobacteria [PDF]

Current Drug Metabolism, 2008
Polymorphic Human arylamine N-acetyltransferase (NAT2) inactivates the anti-tubercular drug isoniazid by acetyltransfer from acetylCoA. There are active NAT proteins encoded by homologous genes in mycobacteria including M. tuberculosis, M. bovis BCG, M. smegmatis and M. marinum. Crystallographic structures of NATs from M. smegmatis and M.
Sim E, Sandy J, Evangelopoulos D, Fullam E, Bhakta S, Westwood I, Krylova A, Lack N, Noble MEM   +8 more
openaire   +3 more sources

Reaction Engineering and Comparison of Electroenzymatic and Enzymatic ATP Regeneration Systems

ChemElectroChem, Volume 10, Issue 22, November 14, 2023., 2023
An electrochemically coupled ATP regeneration by pyruvate oxidase and acetate kinase for the phosphorylation of mevalonate was established and expanded by a polyphosphate kinase. The reaction was characterized and compared with other ATP regenerating systems in terms of the phosphate donor properties and biocatalytic metrics.
Regine Siedentop, Tobias Prenzel, Siegfried R. Waldvogel, Katrin Rosenthal, Stephan Lütz   +4 more
wiley   +1 more source

Pharmacogenetics as part of recommended precision medicine for tuberculosis treatment in African populations: Could it be a reality?

Clinical and Translational Science, Volume 16, Issue 7, Page 1101-1112, July 2023., 2023
Abstract Globally, tuberculosis (TB) is the second most lethal infectious disease. However, in sub‐Saharan Africa, TB has the largest disease burden, with drug‐resistant TB increasingly becoming a concern. The social and economic impact of TB should not be overlooked, especially in areas where healthcare systems are overburdened, and resources need to ...
Carola Oelofse, Carene Anne Alene Ndong Sima, Marlo Möller, Caitlin Uren   +3 more
wiley   +1 more source

Arylamine N-acetyltransferases 3

The Biomedical & Life Sciences Collection, 2007
Edith Sim
openalex   +2 more sources