Results 11 to 20 of about 7,533 (241)
Antioxidants, 2023 Paraoxonase-1 (PON1) is an antioxidant enzyme associated with high-density lipoproteins (HDL). Reduced serum PON1 activity is found in diseases marked by oxidative stress and inflammation, but its role in obesity remains unclear.
Helena Castañé +10 more
doaj +2 more sources
Paraoxonase and arylesterase activity in bladder cancer [PDF]
Türk Üroloji Dergisi/Turkish Journal of Urology, 2017 Oxidative stress is the main pathogenetic mechanism in bladder cancer among many other causes. We aimed to investigate whether a potential relationship exists between bladder cancer and the activities of paraoxonase (PON1) and arylesterase (ARE) enzymes.The study included 56 patients with bladder cancer, and 57 healthy individuals.
Utangac, Mehmet Mazhar +6 more
openaire +4 more sources
Genetics and Molecular Biology, 2018 Paraoxonase 1 (PON1) is a serum enzyme associated with high density lipoprotein (HDL) regulation through its paraoxonase and arylesterase activity. PON1 inhibits the oxidation of HDL and low density lipoprotein (LDL), and is involved in the pathogenesis ...
Muhammad Idrees +7 more
doaj +2 more sources
Evaluation of paraoxonase, arylesterase, and homocysteine thiolactonase activities in patients with diabetes and incipient diabetes nephropathy [PDF]
Journal of Medical Biochemistry, 2019 Background: The aim of this study is to examine the relationship among the changes in activities of paraoxonase (PON), arylesterase (ARE) and homocysteine thiolactonase (HTLase) enzyme having antioxidant properties and the development of diabetic ...
Ayan Durmu§ +6 more
doaj +2 more sources
Romanian Journal of Laboratory Medicine, 2018 Introduction: Reduced serum levels of paraoxonase 1 (PON1) activities are associated with diseases involving increased oxidative stress, such as acute coronary syndrome.
Ciumărnean Lorena +9 more
doaj +2 more sources
Clinics, 2018 OBJECTIVES: Consumption of toxic species of mushrooms may have detrimental effects and increase oxidative stress. Paraoxonase, arylesterase and glutathione-S-transferase are antioxidants that resist oxidative stress.
Sevki Hakan Eren +4 more
doaj +2 more sources
Gut Bacterium Lysinibacillus Sphaericus Exacerbates Aspirin-induced Intestinal Injury by Production of Carboxylesterase EstB. [PDF]
Adv Sci (Weinh)Schematic overview illustrating the detrimental role of gut microbiota in aspirin‐induced intestinal injury. L. sphaericus and its secreted carboxylesterase EstB are identified as key drivers that catalyze aspirin hydrolysis into salicylic acid, thereby exacerbating intestinal injury. Inhibition of EstB by the dietary compound flavanomarein effectively
Zhao Z +13 more
europepmc +2 more sources
Noncatalytic Functions Are Required for MPO and PON1 in Modulating the Involvement of Monocytes and Endothelial Cells in Atherosclerosis. [PDF]
Biochem Res IntHigh‐density lipoproteins (HDLs) are deeply implicated in atherosclerosis. HDL, myeloperoxidase (MPO), and paraoxonase‐1 (PON1) form a functional ternary complex where PON1 partially inhibits the MPO activity, and MPO in turn partially inactivates PON1.
Li Y, Liu Y, Cheng Y.
europepmc +2 more sources
Disease Markers, 2022 Aim To review and compare the PON-1 arylesterase activity between coronary artery disease (CAD) and non-CAD patients. Methods Data were obtained by searching MEDLINE and Scopus for all investigations published between January 1, 2000 and March 1, 2021 ...
M. Zuin +9 more
semanticscholar +1 more source
Clinical and Experimental Medicine (Testo stampato), 2022 Human serum paraoxonase-1 (PON-1) is a critical antioxidant defense system against lipid oxidation. Decreased PON-1 activity has been associated with systemic oxidative stress in several disease states.
Stefania Bassu +5 more
semanticscholar +1 more source