Results 91 to 100 of about 2,480 (127)

Mechanisms and Design Principles of Proteolysis-Targeting Chimeras and Their Emerging Applications. [PDF]

ACS Pharmacol Transl Sci
Knoll N, Neamati N, Üren A.
europepmc   +1 more source

Dual functionality of MDM2 in PROTACs expands the horizons of targeted protein degradation. [PDF]

Biomark Res
Zhao J, Chen H, Liang C.
europepmc   +1 more source

Microporous structures on mineralized collagen mediate bone restoration by promoting nucleolin secretion to induce macrophage M2 polarization. [PDF]

Regen Biomater
Li J, Liu Y, Meng C, Zhang Y, Luan Y, Liu K, Zhang L, Liu F, Luo X, Zhang B.   +9 more
europepmc   +1 more source

Aptamer-Nanoconjugates as Potential Theranostics in Major Neuro-Oncological and Neurodegenerative Disorders. [PDF]

Pharmaceutics
Tauser RG, Lupascu FG, Profire BS, Iacob AT, Vasincu IM, Apotrosoaei M, Chirliu OM, Lupascu D, Profire L.   +8 more
europepmc   +1 more source

Neutrophil-Inspired Film for Nonadhesive Capture of Tumor Cells through Synergistic Functionalization of Zwitterions and Aptamers. [PDF]

Chem Bio Eng
Li Y, Shu R, Lu D, Zeng C, Qi F, Chen S, Zhang L, Tang Z.   +7 more
europepmc   +1 more source

DNA Tweezers with Replaceable Clamps for the Targeted Degradation of Cell Membrane Proteins. [PDF]

Pharmaceutics
Sun Y, Huang Y, Chen D, Hu S, Pan T, Liu Y, Wang R, Tan W.   +7 more
europepmc   +1 more source

Albumin-conjugation enables improved tumor targeting of aptamers via SPECT imaging. [PDF]

Mol Ther Nucleic Acids
Yang S, Zheng C, Cheng S, Wen L, Li P, Li J, Lan X, Jiang D.   +7 more
europepmc   +1 more source

Aptamer-based applications in delivering cancer gene therapies and beyond: state of the art and the missing links to clinical translation. [PDF]

Adv Drug Deliv Rev
Coppola G, Cennamo F, Ciccone G, Ibba ML, Ruscio AD, Vito AD, Esposito CL, Catuogno S.   +7 more
europepmc   +1 more source

Development of dual aptamers-functionalized c-MET PROTAC degraders for targeted therapy of osteosarcoma. [PDF]

Theranostics
Fu X, Huang J, Chen X, Xie D, Chen H, Liang Z, Wang Z, Liang Y, Lu A, Liang C.   +9 more
europepmc   +1 more source

Innovative Applications of Nucleic Acid Aptamers in Colorectal Cancer Diagnosis and Therapy: From Selection Optimization to Clinical Translation. [PDF]

Int J Nanomedicine
Lu JF, Zhang XR, Liu Y, Zhang CL, Wang L, Liu ZQ, Cai J, Yi HW.   +7 more
europepmc   +1 more source