Results 121 to 130 of about 98,201 (305)

Exploring vaginal microbiota–tissue resident stem cell crosstalk: VCAM1/Akt signaling ‐mediated enhancement of regenerative capacity

open access: yesInterdisciplinary Medicine, EarlyView.
Vaginal microbiota‐derived secretory factors enhance the regenerative capacity of human endometrial stem cells by upregulating VCAM1 and activating PI3K/Akt signaling. This microbiota–stem cell crosstalk promotes self‐renewal, migration, multilineage differentiation, and metabolic reprogramming in vitro and in vivo, establishing a novel microbiota ...
Soo‐Rim Kim   +6 more
wiley   +1 more source

Ascorbate in the ocular lens

open access: yes, 2006
Purpose: First, we intended to establish a method for sample preparation for measurement of ascorbate in whole rat and guinea pig lenses utilizing ultrafiltration and high performance liquid chromatography with ultraviolet radiation detection.
Vino C Jr Mody (19491604)
core   +1 more source

Examining the links between vitamin C and schizophrenia spectrum disorders: a systematic review and meta-analysis on circulating levels and supplementation outcomes

open access: yesFrontiers in Nutrition
IntroductionSchizophrenia (SCZ) is a debilitating psychiatric condition characterized by psychotic symptoms such as hallucinations, delusions, and disorganized thought.
Gaatha Suresh   +3 more
doaj   +1 more source

Pharmacokinetic and anti-cancer properties of high dose ascorbate in solid tumours of ascorbate-dependent mice

open access: yes, 2016
Despite recent evidence for an anti-tumour role for high-dose ascorbate, potential mechanisms of action are still unclear. At mM concentrations that are achieved with high-dose intravenous administration, autoxidation of ascorbate can generate cytotoxic ...
Strother, RM   +7 more
core   +1 more source

Air Pollution Quinones Impair Intestinal Barrier Integrity and Endoplasmic Reticulum in Differentiated Caco‐2 Cells

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Particulate matter (PM) is a major global health threat, linked to millions of deaths annually. Beyond inhalation, PM components reach the gastrointestinal tract through the mucociliary escalator or contaminated food and water. Among PM's organic fraction, redox‐active quinones such as 1,2‐naphthoquinone (NQ) and 9,10‐phenanthrenequinone (PQ ...
Franco Cervellati   +6 more
wiley   +1 more source

Exogenous Ergothioneine and Glutathione Limit Postharvest Senescence of Arugula

open access: yesAntioxidants
Arugula is susceptible to postharvest deterioration. We tested the impact of exogenous antioxidant (i.e., ergothioneine and glutathione) dip solutions on arugula quality during storage at 4 °C or 10 °C for up to 17 days relative to a non-antioxidant ...
Dhanya Sivakumar, Gale Bozzo
doaj   +1 more source

Gold(I)‐Catalyzed Annulation of Pyridines Containing Alkyne: Synthesis of N‐Alkenyl Pyridonyl Azides via Rearrangement

open access: yesJournal of Heterocyclic Chemistry, EarlyView.
One‐pot gold(I)‐catalysts synthesis was developed in order to prepare N‐alkenyl 2‐pyridonyl azides. This method provides a series of N‐alkenyl 2‐pyridonyl azides in moderate to excellent yields (up to 94%). ABSTRACT A novel strategy, involving the preparation of gold‐catalyzed cyclization salts and the rearrangement of these salts in the presence of ...
Ali Osman Karatavuk
wiley   +1 more source

Oxygen Depletion and the Role of Cellular Antioxidants in FLASH Radiotherapy: Mechanistic Insights from Monte Carlo Radiation-Chemical Modeling

open access: yesAntioxidants
FLASH radiotherapy is a novel irradiation modality that employs ultra-high mean dose rates exceeding 40–150 Gy/s, far surpassing the typical ~0.03 Gy/s used in conventional radiotherapy.
Israth Rabeya   +2 more
doaj   +1 more source

Prospects for enhancement of the soluble antioxidants, ascorbate and glutathione

open access: yes, 2001
Ascorbic acid (vitamin C) and the tripeptide thiol, glutathione gamma-glutamyl cysteinyl glycine (glutathione) are the major low molecular weight soluble antioxidants in plant cells.
Foyer, C. H., Christine H. Foyer
core   +1 more source

Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy