Results 101 to 110 of about 95,783 (301)

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Serum ascorbic acid concentration in patients with acute Falciparum malaria infection: possible significance

Brazilian Journal of Infectious Diseases
Falciparum malaria infection is associated with significant destruction of erythrocytes. This leads to the release of toxic metabolic products, including oxidant compounds.We measured the serum concentration of the antioxidant, ascorbic acid, in 129 ...
Garba Ibrahim Hassan, Ubom Gregory, Haruna Maryam   +2 more
doaj   +1 more source

Enzymes Involved in Antioxidant and Detoxification Processes Present Changes in the Expression Levels of Their Coding Genes under the Stress Caused by the Presence of Antimony in Tomato

Plants
Currently, there is an increasing presence of heavy metals and metalloids in soils and water due to anthropogenic activities. However, the biggest problem caused by this increase is the difficulty in recycling these elements and their high permanence in ...
Francisco Luis Espinosa-Vellarino, Inmaculada Garrido, Ilda Casimiro, Ana Cláudia Silva, Francisco Espinosa, Alfonso Ortega   +5 more
doaj   +1 more source

Calcium and L-histidine effects on ascorbate-glutathione cycle components under nickel-induced oxidative stress in tomato plants

, 2014
The effects of NiSO4, calcium, and L-histidine (His) on the components of ascorbate-glutathione cycle, antioxidant enzymes and lipid peroxidation in a tomato cultivar Early Urbana Y was investigated.
H. Mozafari, F. Rezanejad, S. Pourseyedi, M. M. Yaghoobi, Z. Asrar   +4 more
core   +1 more source

Effects of a novel ascorbate-based protocol on infarct size and ventricle function in acute myocardial infarction patients undergoing percutaneous coronary angioplasty

, 2016
Introduction : This study was designed to test the hypothesis that high-dose ascorbate prior to reperfusion followed by low chronic oral doses ameliorate myocardial reperfusion injury (MRI) in acute myocardial infarction patients subjected to primary ...
Tamara Palavecino, Gonzalo Pereira, Cristóbal Ramos, Juan C. Prieto, Ramón Rodrigo, Nicolás Valls, Viviana Noriega, Jaime González-Montero, Rubén Aguayo, Roberto Brito, Ángel Puentes, Juan G. Gormaz   +11 more
core   +1 more source

Peptide Marriages: Modular Assembly of Multi‐Agonist Therapeutics

Chemistry – A European Journal, EarlyView.
A modular polyethylene glycol (PEG) scaffold enables rapid assembly of dual peptide agonists using strain‐promoted azide–alkyne cycloaddition (SPAAC) and copper‐catalysed azide–alkyne cycloaddition (CuAAC). Glucagon‐like peptide‐1 (GLP‐1) and amylin agonists were combined with controlled valency, yielding low‐picomolar activity and receptor‐selective ...
Kristina A. Kostadinova, Jan L. Venne, Sona Krajcovicova, James Dodgson, Wouter F. J. Hogendorf, Thomas E. Nielsen, David Hymel, Hannah Bolt, Andie Collinson, Jason Day, Jefferson Revell, David R. Spring   +11 more
wiley   +1 more source

Physicochemical Changes and Antioxidant Metabolism of Actinidia arguta Fruit (Kiwiberry) Under Various Cold-Storage Conditions

Molecules
Actinidia arguta (kiwiberry) is a fruit with significant health benefits, and research continues to identify factors that enhance its storability while maintaining quality.
Barbara Łata, Rafał Wołosiak, Ewa Majewska, Beata Drużyńska, Małgorzata Piecyk, Katarzyna Najman, Anna Sadowska, Piotr Latocha   +7 more
doaj   +1 more source

Biphasic effects of L-ascorbate on the tumoricidal activity of non-thermal plasma against malignant mesothelioma cells

, 2016
Non-thermal plasma (NTP) is a recently developed technology that elicits a variety of biological effects. This includes cancer cell-specific cytotoxicity, which is mainly attributed to the regional generation of reactive oxygen species (ROS).
Wang, Yue, Okazaki, Yasumasa, Mizuno, Masaaki, Hori, Masaru, Ito, Fumiya, Shi, Lei, Tanaka, Hiromasa, Richardson, Des R, Toyokuni, Shinya   +8 more
core   +1 more source

An Electrophilic Uridine Building Block for Post‐Synthetic RNA Modification as Exemplified for Spin Labeling

Chemistry – A European Journal, EarlyView.
An electrophilic 5‐isothiocyanatomethyl uridine building block enables modular post‐synthetic RNA labeling with primary amine‐containing probes. Positioning the functionality in the major groove minimizes structural perturbation and allows facile conjugation of sensitive tags such as TEMPO spin labels for paramagnetic relaxation enhancement studies ...
Lisa Ruetz, Sonja Leiner, Alessandro Marotto, Raphael Plangger, Christoph Kreutz   +4 more
wiley   +1 more source

Ascorbate Oxidase

Journal of Biological Chemistry, 1973
M H, Lee, C R, Dawson
openaire   +2 more sources