Results 111 to 120 of about 89,167 (310)

Specificity of Ascorbate Analogs for Ascorbate Transport [PDF]

open access: yesJournal of Biological Chemistry, 1999
Steven C. Rumsey   +7 more
openaire   +1 more source

Ascorbate in the ocular lens [Elektronisk resurs] [PDF]

open access: yes, 2006
Purpose: First, we intended to establish a method for sample preparation for measurement of ascorbate in whole rat and guinea pig lenses utilizing ultrafiltration and high performance liquid chromatography with ultraviolet radiation detection.
Mody, VCJ,
core  

TWEAK/Fn14 Signaling Drives Oxidative Cardiac Injury in Systemic Lupus Erythematosus: Evidence From Patient Biomarker Studies, Lupus Mouse Models, and Cardiomyocyte Assays

open access: yesArthritis &Rheumatology, EarlyView.
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/fibroblast growth factor–inducible 14 (Fn14) signaling in SLE‐related ...
Yale Liu   +12 more
wiley   +1 more source

Serum ascorbic acid concentration in patients with acute Falciparum malaria infection: possible significance

open access: yesBrazilian Journal of Infectious Diseases
Falciparum malaria infection is associated with significant destruction of erythrocytes. This leads to the release of toxic metabolic products, including oxidant compounds.We measured the serum concentration of the antioxidant, ascorbic acid, in 129 ...
Garba Ibrahim Hassan   +2 more
doaj   +1 more source

Spray‐Dried Engineered Escherichia coli Whole‐Cell Biocatalysts Enable Cell Recycling and In Vivo α‐Ketoglutarate and NADPH Regeneration for Efficient Codeine Manufacture

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT A recombinant whole‐cell biocatalytic approach provides several advantages over isolated enzymes, such as improved enzyme stability, in vivo cofactor regeneration, and the facilitation of cascade reactions within a single cell. Whole‐cell biocatalysis has gained attention in medicinal opioid production, due to its technical and economic ...
Ali Jahanian   +4 more
wiley   +1 more source

Enzymes Involved in Antioxidant and Detoxification Processes Present Changes in the Expression Levels of Their Coding Genes under the Stress Caused by the Presence of Antimony in Tomato

open access: yesPlants
Currently, there is an increasing presence of heavy metals and metalloids in soils and water due to anthropogenic activities. However, the biggest problem caused by this increase is the difficulty in recycling these elements and their high permanence in ...
Francisco Luis Espinosa-Vellarino   +5 more
doaj   +1 more source

Ultraviolet radiation cataract development and ascorbate supplementation [PDF]

open access: yes, 2008
Background: Cataract is the major cause of blindness in the world, and long-term solar ultraviolet radiation (UVR) is a major risk factor. The pathogenesis of UVRinduced cataract is studied in various animal models and cell systems.
Vino C Jr Mody (19491604)
core  

Synthesis and Reactivity of 3‐Aminosydnones in Cycloaddition Reactions With Alkynes

open access: yesChemistry – A European Journal, EarlyView.
The synthesis, functionalization, and reactivity as dipoles of 3‐aminosydnones have been investigated. These neglected compounds undergo smooth cycloaddition reactions with strained alkynes, leading to 1‐aminopyrazoles. ABSTRACT We present in this article the synthesis, functionalization, and properties of 3‐aminosydnones, a forgotten class of ...
Apolline Dominic   +7 more
wiley   +1 more source

Peptide Marriages: Modular Assembly of Multi‐Agonist Therapeutics

open access: yesChemistry – A European Journal, EarlyView.
A modular polyethylene glycol (PEG) scaffold enables rapid assembly of dual peptide agonists using strain‐promoted azide–alkyne cycloaddition (SPAAC) and copper‐catalysed azide–alkyne cycloaddition (CuAAC). Glucagon‐like peptide‐1 (GLP‐1) and amylin agonists were combined with controlled valency, yielding low‐picomolar activity and receptor‐selective ...
Kristina A. Kostadinova   +11 more
wiley   +1 more source

Physicochemical Changes and Antioxidant Metabolism of Actinidia arguta Fruit (Kiwiberry) Under Various Cold-Storage Conditions

open access: yesMolecules
Actinidia arguta (kiwiberry) is a fruit with significant health benefits, and research continues to identify factors that enhance its storability while maintaining quality.
Barbara Łata   +7 more
doaj   +1 more source

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