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RNA-Ascorbate Interaction

Journal of Biomolecular Structure and Dynamics, 1998
Ascorbic acid and divalent iron salts have been widely used to investigate the effects of reactive oxygen species in different biological targets such as nucleic acids, proteins and lipids. This study was designed to examine the interaction of yeast RNA with vitamin C in aqueous solution at physiological pH with drug/RNA(P)(P=phosphate) molar ratios of
M C, Djoman   +3 more
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A unique function for ascorbate

Medical Hypotheses, 1991
Vitamin C is a reducing substance, an electron donor. When vitamin C donates its two high-energy electrons to scavenge free radicals, much of the resulting dehydroascorbate is re-reduced to vitamin C and therefore used repeatedly. Conventional wisdom is correct in that only small amounts of vitamin C are necessary for this function because of its ...
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Ascorbate in the Carotid Body

2003
In previous work, we found that ascorbic acid (AA) or ascorbate is present in the carotid body of the cat (Pokorski and Gonet, 1997), the animal that, as opposed to man and other primates, is capable of synthesizing ascorbate (Chatterjee, 1973). The content of ascorbate is decreased in the hypoxic carotid body, which implies the compound might be ...
Aneta, Dymecka   +4 more
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Absorption of ascorbic acid and ascorbic sulfate and ascorbate metabolism in common carp (Cyprinus carpio L.)

Journal of Comparative Physiology B, 1990
Ascorbate metabolism was analyzed in fasted common carp and carp offered diets lacking ascorbic acid or supplemented with ascorbic acid (AA) or ascorbic sulfate (AS). Ascorbic acid and ascorbic sulfate were analyzed in the contents collected from various parts of the digestive tract. The major site of the dietary ascorbate absorption was located in the
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Ascorbic Acid and Cancer

1996
The relationship of ascorbic acid to cancer has, unfortunately, been one of some confusion. While there have been clinical reports suggesting that high doses of ascorbic acid (vitamin C) can exert an inhibitory effect on the development of cancer, these reports have not been adequately corroborated.
G, Shklar, J L, Schwartz
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Ascorbic Acid in Chloroplasts

Nature, 1963
ASCORBIC acid is found in all green plants, although its concentration may vary greatly. Probably the largest concentration recorded is in the endocarp of the walnut, Juglans regia, which contains between 2 and 3 per cent of the fresh weight. The smallest concentration recorded is possibly that in the vegetable marrow, Cucurbita ovifera, 0.002 per cent
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Ascorbic Acid and Warfarin

JAMA: The Journal of the American Medical Association, 1973
To the Editor.— Since Sigell and Fless (214:2035, 1970) mentioned the possible role of ascorbic acid in anticoagulant therapy, letters by Rosenthal (215:1671, 1971), Hume et al (219:1479, 1972), and Smith et al (221:1166, 1972) have related observations on the interaction of ascorbic acid in patients, as well as in dogs and rabbits.
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Ascorbic acid in the brain

Brain Research Reviews, 1993
Ascorbic acid is highly concentrated in the central nervous system. Measurement of the extracellular concentration of ascorbate in animals, mainly by the technique of voltammetry in vivo, has demonstrated fluctuation in release from neuropil, both spontaneously and in response to physical stimulation of the animal and to certain drugs.
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Ascorbate guided conversion of hydrogen peroxide to hydroxyl radical on goethite

Applied Catalysis B: Environmental, 2021
Lizhi Zhang, Yanbiao Shi, Cancan Ling
exaly  

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