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Glypican-1: a modulator of neurodegenerative and tumorigenic pathways. [PDF]
Front NeurosciMani K.
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Shear bond strength analysis of self-etch and total-etch adhesive systems on antioxidant-treated dentin in post-endodontic restoration. [PDF]
Front Dent MedHarish SK, Attavar SH.
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Correction to "Hydroquinone-Free, Tetrahexyldecyl Ascorbate Antioxidant Serum for Hyperpigmented and Photodamaged Skin to Achieve Skin Health". [PDF]
J Cosmet Dermatoleuropepmc +1 more source
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Anaerobic reaction of ascorbate oxidase with ascorbate
Archives of Biochemistry and Biophysics, 1978Abstract Ascorbate oxidase is fully reduced by 4 mol of ascorbate in the absence of air, as monitored by optical and electron paramagnetic resonance spectra. At less than stoichiometric ascorbate concentration there is a slow equilibration between the 605-and 330-nm absorption bands: The 605-nm chromophore is first reduced, then its color reappears ...
L, Avigliano +4 more
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Crystal structure of the ascorbate peroxidase–ascorbate complex
Nature Structural & Molecular Biology, 2003Heme peroxidases catalyze the H2O2-dependent oxidation of a variety of substrates, most of which are organic. Mechanistically, these enzymes are well characterized: they share a common catalytic cycle that involves formation of a two-electron, oxidized Compound I intermediate followed by two single-electron reduction steps by substrate.
Sharp, K.H. +3 more
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Ascorbate Sulfate: A Urinary Metabolite of Ascorbic Acid in Man
Science, 1971Ascorbate-3-sulfate is a significant metabolite of ascorbic acid excreted in human urine. The characteristics of this compound were determined in experiments in which labeling with carbon-14 and tritium was used coupled with cochromatography with synthetic ascorbate-3-sulfate (both labeled and not labeled with sulfur-35) in a variety of solvent and ...
E M, Baker +4 more
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Ascorbate Metabolism in Potato Leaves Supplied with Exogenous Ascorbate
Free Radical Research, 1999Photosynthesis and leaf ascorbate were measured in potato (Solanum tuberosum L.) plants grown in low light and then transferred to high light. Total foliar ascorbate content in low light-grown plants was 4.72+/-0.42 micromol mg(-1)chl. Over 80% of the ascorbate pool was found in the reduced form irrespective of position on the stem.
T, Imai, A H, Kingston-Smith, C H, Foyer
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The regulation of ascorbate biosynthesis
Current Opinion in Plant Biology, 2016We review the regulation of ascorbate (vitamin C) biosynthesis, focusing on the l-galactose pathway. We discuss the regulation of ascorbate biosynthesis at the level of gene transcription (both repression and enhancement) and translation (feedback inhibition of translation by ascorbate concentration) and discuss the eight proteins that have been ...
Sean Bulley, William Laing
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Bioactivation of Nitroglycerin by Ascorbate
Molecular Pharmacology, 2007Bioactivation of nitroglycerin (GTN) into an activator of soluble guanylate cyclase (sGC) is essential for the vasorelaxant effect of the drug. Besides several enzymes that catalyze GTN bioactivation, the reaction with cysteine is the sole nonenzymatic mechanism known so far. Here we show that a reaction with ascorbate results in GTN bioactivation.
Alexander, Kollau +6 more
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