Results 41 to 50 of about 142,838 (307)

ASCORBIC ACID

open access: yesThe Professional Medical Journal, 2018
Objectives: To demonstrate the volume changes that are produced byanthracycline Doxorubicin DOX on the testes of mice and designed to study volumetric changesin DOX affected testes with co-administration of antioxidant Vitamin C. Design: An experimentalstudy. Setting: Institute of Basic Medical Sciences. Dow University of Health Sciences.
Aisha Abdul Haq   +2 more
openaire   +3 more sources

Inuloxin A Inhibits Seedling Growth and Affects Redox System of Lycopersicon esculentum Mill. and Lepidium sativum L.

open access: yesBiomolecules, 2022
Allelochemicals are considered an environment-friendly and promising alternative for weed management, although much effort is still needed for understanding their mode of action and then promoting their use in plant allelopathy management practices. Here,
Alessandra Villani   +4 more
doaj   +1 more source

Role of antioxidative system during the development and senescence of cucumber fruit

open access: yesBiologia Plantarum, 2012
The oxidative processes and antioxidative system in cucumber (Cucumis sativus L.) fruit were determined during development and senescence. Four distinct developmental stages could be delineated during fruit maturation: immature (3-8 d after anthesis, DAA)
C. -L. Qian   +5 more
doaj   +1 more source

Ascorbate as a Bioactive Compound in Cancer Therapy: The Old Classic Strikes Back

open access: yesMolecules, 2022
Cancer is a disease of high mortality, and its prevalence has increased steadily in the last few years. However, during the last decade, the development of modern chemotherapy schemes, new radiotherapy techniques, targeted therapies and immunotherapy has
Jaime González-Montero   +5 more
doaj   +1 more source

Pectic enzymes as potential enhancers of ascorbic acid production through the D-galacturonate pathway in Solanaceae [PDF]

open access: yes, 2018
The increase of L-Ascorbic Acid (AsA) content in tomato (Solanum lycopersicum) is a common goal in breeding programs due to its beneficial effect on human health.
Barone, Amalia   +4 more
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Characterization of the antioxidant system during the vegetative development of pea plants

open access: yesBiologia Plantarum, 2010
The antioxidative system was studied during the development of pea plants. The reduced glutathione (GSH) content was higher in shoots than in roots, but a greater redox state of glutathione existed in roots compared with shoots, at least after 7 d of ...
P. Díaz-Vivancos   +3 more
doaj   +1 more source

Regional sex differences in neurochemical profiles of healthy mice measured by magnetic resonance spectroscopy at 9.4 tesla

open access: yesFrontiers in Neuroscience, 2023
ObjectiveTo determine sex differences in the neurochemical concentrations measured by in vivo proton magnetic resonance spectroscopy (1H MRS) of healthy mice on a genetic background commonly used for neurodegenerative disease models.Methods1H MRS data ...
Ivan Tkáč   +10 more
doaj   +1 more source

Studies on the hyperplasia ('regeneration') of the rat liver following partial hepatectomy. Changes in lipid peroxidation and general biochemical aspects [PDF]

open access: yes, 1990
Using the experimental model of partial hepatectomy in the rat, we have examined the relationship between cell division and lipid peroxidation activity. In rats entrained to a regime of 12 h light/12 h dark and with a fixed 8 h feeding period in the dark
Benedetto, C   +9 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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