Results 51 to 60 of about 21,778 (164)

Characterization of an L-Ascorbate Catabolic Pathway with Unprecedented Enzymatic Transformations

open access: yes, 2019
L-Ascorbate (vitamin C) is ubiquitous in both our diet and the environment. Ralstonia eutropha H16 (Cupriavidus necator ATCC 17699) uses L-ascorbate as sole carbon source but lacks the genes encoding the known catabolic pathways.
Khadija, Bhatti   +11 more
core   +1 more source

The Trypanosoma cruzi vitamin C dependent peroxidase confers protection against oxidative stress but is not a determinant of virulence. [PDF]

open access: yes, 2015
BACKGROUND: The neglected parasitic infection Chagas disease is rapidly becoming a globalised public health issue due to migration. There are only two anti-parasitic drugs available to treat this disease, benznidazole and nifurtimox. Thus it is important
Fortes Francisco, A   +19 more
core   +1 more source

Increasing ascorbate levels in crops to enhance human nutrition and plant abiotic stress tolerance

open access: yes, 2017
Ascorbate (or vitamin C) is an essential human micronutrient predominantly obtained from plants. In addition to preventing scurvy, it is now known to have broader roles in human health, for example as a cofactor for enzymes involved in epigenetic ...
Sean M Bulley   +11 more
core   +1 more source

Ascorbate function and associated transport systems

open access: yes, 2000
: Ascorbate is present in different cell compartments of higher plant cells. At a physiological level, the best-studied phenomena involving ascorbate is its participation in an oxygen scavenging pathway in the chloroplast known as the ascorbate ...
Potters, Geert   +7 more
core  

Pharmacokinetic and anti-cancer properties of high dose ascorbate in solid tumours of ascorbate-dependent mice

open access: yes, 2016
Despite recent evidence for an anti-tumour role for high-dose ascorbate, potential mechanisms of action are still unclear. At mM concentrations that are achieved with high-dose intravenous administration, autoxidation of ascorbate can generate cytotoxic ...
Strother, RM   +7 more
core   +1 more source

Control of ascorbate synthesis by respiration and its implications for stress responses [PDF]

open access: yes, 2003
We show for the first time that respiration can control ascorbate (AA) synthesis in plants. Evidence for this control is provided by (a) the localization of L-galactono-1,4-lactone dehydrogenase (GalLDH), the terminal enzyme in AA biosynthesis, with ...
Foyer, C. H.   +13 more
core   +1 more source

Studies on Ascorbic Acid. VI

open access: yesJournal of the agricultural chemical society of Japan, 1938
5mgのAscorbin酸の37±1°に於ける自己酸化に對しVitamin A原液(100,000 I.U.)を0.0~0.2cc作用せしむる時0.0~0.0005ccまでは自己酸化抑制作用は發現せず, 0.001ccに於いて漸く發現し而して0.12ccまではVitamin Aの作用量と共に抑制作用は増大し0.12ccに於いて最大點に達し0.14cc以上に於いては抑制作用は消滅し酸化促進作用と化し而も此の作用は量比的である.但し本實驗に於てはVitamin AのAceton溶液を用ゐたから實驗値に對して幾分の誤差はまぬかれないであらう.
openaire   +8 more sources

Effects of a novel ascorbate-based protocol on infarct size and ventricle function in acute myocardial infarction patients undergoing percutaneous coronary angioplasty

open access: yes, 2016
Introduction : This study was designed to test the hypothesis that high-dose ascorbate prior to reperfusion followed by low chronic oral doses ameliorate myocardial reperfusion injury (MRI) in acute myocardial infarction patients subjected to primary ...
Tamara Palavecino   +11 more
core   +1 more source

Ascorbate-Deficient vtc2 Mutants in Arabidopsis Do Not Exhibit Decreased Growth

open access: yes, 2016
In higher plants the L-galactose pathway represents the major route for ascorbate biosynthesis. The first committed step of this pathway is catalyzed by the enzyme GDP-L-galactose phosphorylase and is encoded by two paralogs in Arabidopsis – VITAMIN C2 ...
B Lim (13411716)   +3 more
core  

The ascorbate-driven reduction of extracellular ascorbate free radical by the erythrocyte is an electrogenic process

open access: yes, 2001
Erythrocytes can reduce extracellular ascorbate free radicals by a plasma membrane redox system using intracellular ascorbate as an electron donor. In order to test whether the redox system has electrogenic properties, we studied the effect of ascorbate ...
Van der Zee, Jolanda   +5 more
core   +1 more source

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