Are leaf hydrogen peroxide concentrations commonly overestimated? The potential influence of artefactual interference by tissue phenolics and ascorbate [PDF]
, 2002 We have examined the authenticity of two methods for determination of H2O2 in leaf tissue. We show that the high concentrations of ascorbic acid present in leaf extracts interfere with both techniques. In the chromogenic peroxidase-coupled assay, H2O2 is
Foyer, C. H. +5 more
core +1 more source
Ascorbate Is a Primary Antioxidant in Mammals [PDF]
, 2022 Ascorbate (vitamin C in primates) functions as a cofactor for a number of enzymatic reactions represented by prolyl hydroxylases and as an antioxidant due to its ability to donate electrons, which is mostly accomplished through non-enzymatic reaction in ...
Bo, Tomoki +5 more
core +1 more source
Apatone® induces endometrioid ovarian carcinoma (MDAH 2774) cells to undergo karyolysis and cell death by autoschizis: A potent and safe anticancer treatment [PDF]
, 2015 Ovarian cancers are still the most lethal gynecologic malignancy. As a novel strategy against this poor outcome cytotoxic alterations induced by a pro-oxidant treatment on human ovarian endometrioid carcinoma (MDAH 2774) cells are revisited by using ...
Gilloteaux, Jacques +12 more
core +1 more source
Anti-oxydants d’origine alimentaire : diversité, modes d’action anti-oxydante, interactions
Oléagineux, Corps gras, Lipides, 2006 Antioxidants of food origin (tocopherols, carotenoids, ascorbate, polyphenols) exert synergistic (tocopherols and ascorbate, carotenoids and ascorbate) or complementary (tocopherols ands carotenoids, ascorbate and polyphenols) antioxidant actions.
Léger Claude Louis
doaj +1 more source
An upstream open reading frame is essential for feedback regulation of ascorbate biosynthesis in arabidopsis [PDF]
, 2015 Ascorbate (vitamin C) is an essential antioxidant and enzyme cofactor in both plants and animals. Ascorbate concentration is tightly regulated in plants, partly to respond to stress.
Dare, Andrew P. +10 more
core +1 more source
Characterization of an L-Ascorbate Catabolic Pathway with Unprecedented Enzymatic Transformations [PDF]
, 2019 L-Ascorbate (vitamin C) is ubiquitous in both our diet and the environment. Ralstonia eutropha H16 (Cupriavidus necator ATCC 17699) uses L-ascorbate as sole carbon source but lacks the genes encoding the known catabolic pathways.
Khadija, Bhatti +11 more
core +1 more source
Increasing ascorbate levels in crops to enhance human nutrition and plant abiotic stress tolerance [PDF]
, 2017 Ascorbate (or vitamin C) is an essential human micronutrient predominantly obtained from plants. In addition to preventing scurvy, it is now known to have broader roles in human health, for example as a cofactor for enzymes involved in epigenetic ...
Sean M Bulley +11 more
core +1 more source
Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach
FEBS Letters, EarlyView.The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Ascorbate function and associated transport systems [PDF]
, 2000 : Ascorbate is present in different cell compartments of higher plant cells. At a physiological level, the best-studied phenomena involving ascorbate is its participation in an oxygen scavenging pathway in the chloroplast known as the ascorbate ...
Potters, Geert +7 more
core