Results 61 to 70 of about 89,167 (310)

Effects of NaCl on the response of Mesembryanthemum crystallinum callus to Botrytis cinerea infection

Biologia Plantarum, 2011
Callus of the halophyte Mesembryanthemum crystallinum was used to study the effect of NaCl on the response to Botrytis cinerea infection. The fungus easily colonized the callus surface and the intercellular spaces.
E. Kuźniak, B. Gabara, M. Skłodowska, M. Libik-Konieczny, Z. Miszalski   +4 more
doaj   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Analysis of High-Dose Ascorbate-Induced Cytotoxicity in Human Glioblastoma Cells and the Role of Dehydroascorbic Acid and Iron

Antioxidants
Several studies have demonstrated, both in vitro and in animal models, the anti-tumor efficacy of high-dose ascorbate treatment against a variety of tumor entities, including glioblastoma, the most common and aggressive primary malignant brain tumor. The
Alban Piotrowsky, Markus Burkard, Katharina Hammerschmidt, Hannah K. Ruple, Pia Nonnenmacher, Monika Schumacher, Christian Leischner, Susanne Berchtold, Luigi Marongiu, Thomas A. Kufer, Ulrich M. Lauer, Olga Renner, Sascha Venturelli   +12 more
doaj   +1 more source

Potentiometric measurement of ascorbate by using a solvent polymeric membrane electrode [PDF]

, 2008
A novel potentiometric method for the determination of ascorbate is described in this communication. It is based on ascorbate oxidation with permanganate which is continuously released from the inner reference solution of a ligand-free tridodecylmethyl ...
Su, Qingmei, Yin, Tanji, Guo, Huimin, Qin, Wei   +3 more
core  

Ligand‐Defined Interfacial Chemistry Enables Instant and Sequence‐General DNA Chemisorption on Gold Nanoparticles Toward Label‐Free SERS With Single‐Base Resolution

Advanced Science, EarlyView.
Ascorbic Acid‐Engineered Interface Enables Universal DNA Functionalization on Gold Nanoparticles: Attenuating electrostatic repulsion and leveraging synergistic hydrogen‐bonding interactions significantly lowers the kinetic barrier for DNA adsorption, enabling rapid and sequence‐general functionalization of non‐thiolated DNA‐requiring only a single ...
Guangping Li, Cheng Wang, Xinyue Wu, Zhongxiang Ding, Heng Gao, Zhonggang Liu, Yu Zhang, Jinai Chen, Feng Wang, Honglin Liu   +9 more
wiley   +1 more source

Sodium Ascorbate‐Accelerated Gelling Hydrogels With Rapid Self‐Mineralized Capacity for Chronic Wounds

Advanced Science, EarlyView.
An immunoregulatory hydrogel based on sodium ascorbate (SA)‐accelerated gelation and in situ self‐mineralization is prepared here. Such a hydrogel is constructed by mixing benzaldehyde‐ and cyanoacetate‐functionalized dextran with silver nitrate (AgNO3) and SA, enabling the ultrafast solidification and in situ self‐mineralization of silver ...
Xiaoya Ding, Wei Yang, Wenzhao Li, Guifang Xu, Yuanjin Zhao   +4 more
wiley   +1 more source

Redox regulation of peroxiredoxin and proteinases by ascorbate and thiols during pea root nodule senescence [PDF]

, 2006
Groten K, Dutilleul C, van Heerden PDR, et al. Redox regulation of peroxiredoxin and proteinases by ascorbate and thiols during pea root nodule senescence. FEBS LETTERS.
Foyer, C. H., Dietz, K., Foyer, C., van Heerden, Philippus D.R., Bernard, S., van Heerden, PDR, Dutilleul, C., Finkemeier, Iris, Finkemeier, I, Dutilleul, C, Groten, Karin, Groten, K, Bernard, S, Groten, K., Van Heerden, P. D. R., Dietz, K-J., Vanacker, N, Groten, K. ; https://orcid.org/, Foyer, Christine H., Foyer, CH, Vanacker, Hélène, Bernard, Stéphanie, Dietz, Karl-Josef, Heerden, V., Dutilleul, Christelle, Finkemeier, I., Vanacker, H.   +26 more
core   +2 more sources

Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity

Advanced Science, EarlyView.
Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau, Helen Broghammer, Claudia Gebhardt, Anne Hoffmann, Tobias Hagemann, Şeyma Midilli, Rachel S. Zimmer, Kristin Schubert, Vasiliki Karagiannakou, Anastasia Georgiadi, Mario Ost, Martin Krüger, Lisa Roth, Kerstin Krause, Nora Klöting, Maria Keller, Martin Wabitsch, Rima Nuwayhid, Roland H. Stimson, Michael Stumvoll, Matthias Blüher, Juliane Weiner, John T. Heiker   +22 more
wiley   +1 more source

Suppression of tomato SlGGP aggravates methyl viologen-mediated oxidative stress

Biologia Plantarum, 2016
Ascorbate (AsA) is an important antioxidant that can scavenge reactive oxygen species to protect plant cells against oxidative stress. Guanosine 5'-diphosphate (GDP)-L-galactose phosphorylase (GGP) is a key enzyme in the AsA biosynthetic pathway.
D.-Y. Yang, N.-N. Ma, Z.-M. Liu, X.-C. Ma, S.-J. Zhao, Q.-W. Meng   +5 more
doaj   +1 more source