Results 41 to 50 of about 5,480 (216)

Effects of tapering tumor necrosis factor inhibitor on the achievement of inactive disease in patients with axial spondyloarthritis: a nationwide cohort study

Arthritis Research & Therapy, 2019
Objectives To investigate the association between the extent of tapering tumor necrosis factor inhibitor (TNFi) and the likelihood of achieving inactive disease in patients with axial spondyloarthritis (axSpA) Methods We analyzed 1575 1-year follow-up ...
Jun Won Park, Hyoun-Ah Kim, Kichul Shin, Yong-Beom Park, Tae-Hwan Kim, Yeong Wook Song, Eun Young Lee   +6 more
doaj   +1 more source

Disease activity guided stepwise tapering or discontinuation of rhTNFR:Fc, an etanercept biosimilar, in patients with ankylosing spondylitis: a prospective, randomized, open-label, multicentric study

Therapeutic Advances in Musculoskeletal Disease, 2020
Background: The aim of this study was to evaluate disease-activity-guided stepwise tapering or discontinuation of rhTNFR:Fc, an etanercept biosimilar, in patients with ankylosing spondylitis (AS) in a prospective, randomized, open-label, multicentric ...
Ting Zhang, Jianing Zhu, Dongyi He, Xiaowei Chen, Hongzhi Wang, Ying Zhang, Qin Xue, Weili Liu, Guangbo Xiang, Yasong Li, Zhongming Yu, Huaxiang Wu   +11 more
doaj   +1 more source

Spin and orbital fluctuations in non-equilibrium transport through quantum dots: A renormalisation-group analysis

, 2010
We study non-equilibrium current and occupation probabilities of a two-orbital quantum dot. The couplings to the leads are allowed to be asymmetric and orbital dependent as it is generically the case in transport experiments on molecules and nanowires ...
Andergassen, S., Koerting, V., Mueller, S. Y., Schuricht, D.   +3 more
core   +1 more source

Evaluation of dose reduction versus standard dosing for maintenance of remission in patients with spondyloarthritis and clinical remission with anti-TNF (REDES-TNF): study protocol for a randomized controlled trial [PDF]

, 2015
Background: dose reduction schedules of tumor necrosis factor antagonists (anti-TNF) as maintenance therapy in patients with spondyloarthritis are used empirically in clinical practice, despite the lack of clinical trials providing evidence for this ...
Avendaño, Cristina, Calvo, Gonzalo, de Miguel, Eugenio, Gratacós Masmitjà, Jordi, Juanola, Xavier, Pontes García, Caridad, Sanmartí, Raimon, Sanz, Jesús, Torres, Ferran, Universitat Autònoma de Barcelona. Departament de Medicina, Vallano, Antoni   +10 more
core   +3 more sources

Comparison of Ankylosing Spondylitis Disease Activity Score and Bath Ankylosing Spondylitis Disease Activity Index tools in assessment of axial spondyloarthritis activity

Rheumatology
Axial spondyloarthritis (axSpA) is an inflammatory joint disease, in which the dominant symptom is inflammatory back pain. It affects approximately 1% of the population, with a higher incidence in males.
Katarzyna Małgorzata Wiąk-Walerowicz, Ewa Wielosz   +1 more
doaj   +1 more source

Stable high interleukin-17A concentration in patients with ankylosing spondylitis treated with tumor necrosis factor-α inhibitors during a year [PDF]

Терапевтический архив, 2017
Aim. To assess changes in the concentration of interleukin-17A (IL-17A) in patients with ankylosing spondylitis (AS) treated with tumor necrosis factor-α (TNFα) inhibitors during a year. Subjects and methods. Examinations were made in 30 patients (22 (73.
I Z Gaydukova, A P Rebrov, A V Aparkina, E V Khondkaryan   +3 more
doaj   +1 more source

Early clinical response associates with long-term outcomes with ixekizumab in radiographic axial spondyloarthritis

RMD Open
Background The Assessment of SpondyloArthritis international Society-European Alliance of Associations for Rheumatology recommendations for axial spondyloarthritis (axSpA) management include patient assessment for biological disease-modifying ...
Sofia Ramiro, James Cheng-Chung Wei, Louis Bessette, Soyi Liu-Leage, Cédric Lukas, Rebecca Bolce, Pendleton Wickersham, Tommaso Panni, Boris Janos   +8 more
doaj   +1 more source

Does gender influence outcome measures similarly in patients with spondyloarthritis? Results from the ASAS-perSpA study

RMD Open, 2022
Objectives To investigate the influence of gender on disease outcomes in patients with spondyloarthritis (SpA), including across SpA subtypes.Methods Data from 4185 patients of 23 countries with a diagnosis of axial SpA (axSpA), peripheral SpA (pSpA) or ...
Sofia Ramiro, Maxime Dougados, Anna Molto, Clementina López-Medina, Victoria Navarro-Compán, Diego Benavent, Dafne Capelusnik   +6 more
doaj   +1 more source

Determinants of Difficult‐to‐Manage and Treatment‐Refractory Axial Spondyloarthritis: A Cross‐Sectional Analysis within a Longitudinal Cohort

Arthritis &Rheumatology, Accepted Article.
Objective To estimate the prevalence of difficult‐to‐manage (D2M) and treatment‐refractory (TR) axSpA and to identify factors associated with D2M/TR disease in a longitudinal cohort. Methods We performed a cross‐sectional analysis on data from the Schroeder Arthritis Institute Spondylitis Program cohort.
Patricia Remalante‐Rayco, Laura Passalent, Tina Chim, Hannah Vijayan, Manal Alnasser, Zeynep Baskurt, Robert D. Inman, Nigil Haroon, Denis Poddubnyy   +8 more
wiley   +1 more source

Labor Epidural Analgesia and Autism Spectrum Disorder in Offspring: A Population‐Based Case–Control Study

Autism Research, EarlyView.
ABSTRACT While the immediate benefits of labor epidural analgesia (LEA) are well established, recent studies have raised concerns about possible associations with autism spectrum disorder (ASD). Therefore, we examined the association between LEA and ASD in offspring.
Taniqua T. Ingol, Jessie K. Edwards, Mollie E. Wood, Chantel L. Martin, Gabriel S. Dichter, Keith Feldman, Alan C. Kinlaw, Julie L. Daniels   +7 more
wiley   +1 more source