Results 61 to 70 of about 3,671 (210)

Reduction of CXCR3+CCR6+ CD4+ T Cells and IL‐17+ RORγt+ CD4+ T Cells During Secukinumab Treatment Identifies Patients With Axial Spondyloarthritis Responsive to Subsequent Biologic Therapy

ACR Open Rheumatology, Volume 8, Issue 9, September 2026.
Objective We recently reported an immune profile that stratifies patients with axial spondyloarthritis based on clinical response to secukinumab. We now undertake an exploratory study on the secukinumab nonresponder patients to determine if immunologic changes occur during their initial secukinumab treatment that could determine their next biologic ...
Addison Pacheco, Patricia Remalante‐Rayco, Nigil Haroon, Denis Poddubnyy, Robert D. Inman   +4 more
wiley   +1 more source

How to calculate the ASDAS if the conventional CRP is below the limit of detection or if using high sensitivity CRP? – An analysis in the DESIR cohort

, 2014
Background: The Ankylosing Spondylitis Disease Activity Score (ASDAS) is a composite measure of disease activity in axial spondyloarthritis. Objectives: Our aims were to investigate the most appropriate ASDAS-C-reactive protein (ASDAS-CRP) calculation
Navarro-Compán, Victoria, Heijde, Désirée van der, Machado, P., Machado, Pedro, Navarro-Compan, V., Pers, Jo, van Gaalen, Floris, Machado, Pedro, F, Roux, C., Heijde, D. van der, Landewe, R., Landewé, Robert, Gaalen, Floris A. van, van Der Heijde, Désirée, Roux, Christian, Gaalen, F.A. van   +15 more
core   +1 more source

Effectiveness and drug retention of biologic disease modifying antirheumatic drugs in Korean patients with late onset ankylosing spondylitis

Scientific Reports, 2021
The clinical data on the biologic disease-modifying antirheumatic drug (bDMARD) use in late-onset ankylosing spondylitis (LOAS) is limited. Thus, this study aimed to evaluate the drug efficacy and retention rate of bDMARDs in LOAS and compare it to young-
Se Hee Kim, Hae-Rim Kim, Sang-Heon Lee, Kichul Shin, Hyoun-Ah Kim, Hong Ki Min   +5 more
doaj   +1 more source

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core   +1 more source

Association between ASDAS and NSAID use over time in AS patients.

, 2018
Association between ASDAS and NSAID use over time in AS patients.
Freke Wink (283766), Hendrika Bootsma (51286), Anneke Spoorenberg (283772), Reinhard Bos (576445), Suzanne Arends (283768), Fiona Maas (725094), Marlies J. G. Carbo (5136050), Eveline van der Veer (474668), Elisabeth Brouwer (229171)   +8 more
core   +1 more source

Hematological Inflammation Indices Are Associated With Active Uveitis in Ankylosing Spondylitis

Journal of Clinical Laboratory Analysis, Volume 40, Issue 17, September 2026.
Hematological inflammation indices reflect the systemic inflammatory burden in ankylosing spondylitis. Patients with active uveitis exhibit a distinct pro‐inflammatory profile characterised by increased NLR, PLR, SII, SIRI, and AISI, along with decreased HALP and CALLY scores.
Mesude Seda Aydoğdu, Zarife Ekici Gök
wiley   +1 more source

Achievement of higher thresholds of clinical responses and lower levels of disease activity is associated with improvements in workplace and household productivity in patients with axial spondyloarthritis

Therapeutic Advances in Musculoskeletal Disease, 2023
Background: Patients with active axial spondyloarthritis (axSpA) exhibit more absences and lower levels of productivity in the workplace and household than the general population, which can improve upon treatment.
Martin Rudwaleit, Pedro M. Machado, Vanessa Taieb, Natasha de Peyrecave, Bengt Hoepken, Lianne S. Gensler   +5 more
doaj   +1 more source

How Are Plant‐Based Milk Alternatives Presented Online? A Comparison of Information on Allergens, Nutrients and Sustainability Between Product Types From Selected UK Retailer Websites

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Allergen information and claims, nutrition information and nutrient profiling, dietary preference claims and sustainability claims for plant‐based milk alternatives (PBMAs). ABSTRACT Consumers in the United Kingdom (UK) are increasingly choosing plant‐based milk alternatives (PBMAs) due to food hypersensitivity, nutritional and sustainability ...
Mary Johanna Bula, Lewis W. Wallis, Helen E. Arrowsmith, Christopher A. James, Sally Moore, Pariyarath Sangeetha Thondre   +5 more
wiley   +1 more source

MAPPING FROM THE ANKYLOSING SPONDYLITIS DISEASE ACTIVITY SCORE (ASDAS) TO EQ5D IN PATIENTS WITH AXIAL SPONDYLOARTHRITIS

, 2020
Background: Clinical studies often omit outcomes that allow the direct estimation of Quality Adjusted Life Years (QALYs) for use in cost effectiveness analyses crucial for informing policy decisions.
Chrysanthou, Georgios; id_orcid, Van der Heijde, D., Carvalho, P., Machado, P M, Santos, M J, Hernandez, M, Wailoo, Allan   +6 more
core   +1 more source

Poverty and Social Deprivation in Patients With Pulmonary Arterial Hypertension—A PHAR Analysis

Pulmonary Circulation, Volume 16, Issue 3, July 2026.
ABSTRACT Poverty and social deprivation have been associated with impaired clinical outcomes and survival in several chronic diseases. The association between poverty and clinical outcomes in patients with pulmonary arterial hypertension (PAH) remains unclear.
Roberto J. Bernardo, Di Lu, Haley Hedlin, Daniel Grinnan, Roberto F. Machado, Lana Melendres‐Groves, Jean M. Elwing, Sandeep Sahay, Steven M. Kawut, Jeffrey C. Robinson, Vinicio A. de Jesus Perez, Roham T. Zamanian, PHAR Investigators   +12 more
wiley   +1 more source