Results 121 to 130 of about 10,002 (242)

Recombinant Vaccine Strain ASFV-G-Δ9GL/ΔUK Produced in the IPKM Cell Line Is Genetically Stable and Efficacious in Inducing Protection in Pigs Challenged with the Virulent African Swine Fever Virus Field Isolate Georgia 2010

Pathogens
We have previously reported that the recombinant African Swine Fever (ASF) vaccine candidate ASFV-G-Δ9GL/ΔUK efficiently induces protection in domestic pigs challenged with the virulent strain Georgia 2010 (ASFV-G).
Elizabeth Ramirez-Medina, Ayushi Rai, Nallely Espinoza, Edward Spinard, Ediane Silva, Leeanna Burton, Jason Clark, Amanda Meyers, Alyssa Valladares, Lauro Velazquez-Salinas, Cyril G. Gay, Douglas P. Gladue, Manuel V. Borca   +12 more
doaj   +1 more source

Taking a Promising Vaccine Candidate Further: Efficacy of ASFV-G-ΔMGF after Intramuscular Vaccination of Domestic Pigs and Oral Vaccination of Wild Boar

, 2022
Paul Deutschmann, Tessa Carrau, Julia Sehl‐Ewert, Jan H. Forth, Elisenda Viaplana, Jose Carlos Mancera, Alicia Urniza, Martin Beer, Sandra Blome   +8 more
openalex   +2 more sources

Control of African swine fever virus by siRNA [PDF]

, 2007
African Swine Fever (ASF) is a highly contagious, viral disease of pigs caused by an Asfivirus. It can cause up to 100% of mortality in domestic pigs and European wild boars, although varying degrees of virulence have been shown.
Albina, Emmanuel, Keita, D.
core  

Problemática de la peste porcina africana en Europa. Alternativas futuras [PDF]

, 2017
African swine fever (ASF) is one of the most important infectious diseases of swine. It is a complex disease caused by African swine fever virus (ASFV), the only member of the Asfarviridae family, without available vaccine or effective treatment.
Santamaría Páez, A., Serna Bernaldo, C., Tapias García, A.   +2 more
core   +2 more sources

The African swine fever virus gene MGF_360-4L inhibits interferon signaling by recruiting mitochondrial selective autophagy receptor SQSTM1 degrading MDA5 antagonizing innate immune responses

mBio
Multigene family (MGF) 360 genes, which are African swine fever virus (ASFV) virulence genes, primarily target key host immune molecules to suppress host interferon (IFN) production and interferon-stimulated gene (ISG) transcription, impairing host ...
Hualin Sun, Jifei Yang, Zhonghui Zhang, Mengli Wu, Zhancheng Tian, Ying Liu, Xiaoqiang Zhang, Jianhao Zhong, Songlin Yang, Yikang Chen, Jianxun Luo, Guiquan Guan, Hong Yin, Qingli Niu   +13 more
doaj   +1 more source

Genetic Variation among African Swine Fever Genotype II Viruses, Eastern and Central Europe

Emerging Infectious Diseases, 2014
African swine fever virus (ASFV) was first reported in eastern Europe/Eurasia in 2007. Continued spread of ASFV has placed central European countries at risk, and in 2014, ASFV was detected in Lithuania and Poland.
Carmina Gallardo, Jovita Fernández-Pinero, Virginia Pelayo, Ismail Gazaev, Iwona Markowska-Daniel, Gediminas Pridotkas, Raquel Nieto, Paloma Fernández-Pacheco, Svetlana Bokhan, Oleg Nevolko, Zhanna Drozhzhe, Covadonga Pérez, Alejandro Soler, Denis Kolvasov, Marisa Arias   +14 more
doaj   +1 more source

Protective Efficacy of Live-Attenuated ASFV Vaccine Strains against the Emerging Recombinant ASFV Genotype I/II Strain in Vietnam

African swine fever virus (ASFV) continues to spread globally causing severe economic losses to the pig farmers. Vietnam licensed two live attenuated vaccines based on the ASFV strains ASFV-G-ΔI177L and ASFV-G-ΔMGF, to control the ongoing ASF outbreaks.
Nguyen Van Diep, Nguyen Van Duc, Nguyen Thi Ngoc, Dang Xuan Vu, Tran Ngoc Tiep, Viet Dung Nguyen, Thi Tam Than, Dustin Maydaniuk, Kalhari Goonewardene, Aruna Ambagala, Van Phan Le   +10 more
openaire   +1 more source

Diverse immune cell profiles in ASFV-associated lymphopenia

Animal Diseases
AbstractPathogenic African swine fever virus (ASFV) remains a lethal causative agent in the domestic pig industry, which poses a burden on the swine market and causes substantial socioeconomic losses worldwide. Currently, there are no commercially efficacious vaccines or specific treatments available for ASF prevention and control.
Wenjing Xiong, Haowei Chen, Yanru Chen, Ke Wang, Tingting Lian, Weijia Zhang, Qing Yu, Xiaochen Gao, Jie Su, Qigai He, Xiangru Wang, Junping Yu, Min Cui   +12 more
openaire   +2 more sources

Cholesterol affects African swine fever virus infection [PDF]

, 1989
African swine fever virus (ASFV) enters cells by receptor mediated endocytosis and requires a fusion event between the viral envelope and the limiting membrane of the endosome at low pH. In order to investigate the role of cholesterol in the early stages
Bernardes, C., António, A., Pedroso de Lima, Maria C., Valdeira, M. L.   +3 more
core   +1 more source

Genotype II Live-Attenuated ASFV Vaccine Strains Unable to Completely Protect Pigs against the Emerging Recombinant ASFV Genotype I/II Strain in Vietnam

Vaccines
Background: African swine fever virus (ASFV) continues to spread globally, causing severe economic losses to pig farmers. Vietnam licensed two live attenuated vaccines based on the ASFV strains ASFV-G-ΔI177L and ASFV-G-ΔMGF to control the ongoing ASF outbreaks.
Nguyen Van Diep, Nguyen Van Duc, Nguyen Thi Ngoc, Vu Xuan Dang, Tran Ngoc Tiep, Viet Dung Nguyen, Thi Tam Than, Dustin Maydaniuk, Kalhari Goonewardene, Aruna Ambagala, Van Phan Le   +10 more
openaire   +3 more sources