Results 1 to 10 of about 2,537 (176)

Activities and Structure-Function Analysis of Fission Yeast Inositol Pyrophosphate (IPP) Kinase-Pyrophosphatase Asp1 and Its Impact on Regulation of pho1 Gene Expression.

open access: yesMBio, 2022
Inositol pyrophosphates (IPPs) are signaling molecules that regulate cellular phosphate homeostasis in diverse eukaryal taxa. In fission yeast, mutations that increase 1,5-IP8 derepress the PHO regulon while mutations that ablate IP8 synthesis are PHO ...
Stewart Shuman   +2 more
exaly   +4 more sources

Tandem inactivation of inositol pyrophosphatases Asp1, Siw14, and Aps1 illuminates functional redundancies in inositol pyrophosphate catabolism in fission yeast [PDF]

open access: yesmBio
Inositol pyrophosphates 5-IP7, 1-IP7, and 1,5-IP8 are eukaryal signaling molecules that influence cell physiology, especially phosphate homeostasis. In fission yeast, 1,5-IP8 and 1-IP7 impact gene expression by acting as agonists of RNA 3'-processing and
Beate Schwer   +5 more
doaj   +4 more sources

ATP Hydrolases Superfamily Protein 1 (ASP1) Maintains Root Stem Cell Niche Identity through Regulating Reactive Oxygen Species Signaling in Arabidopsis [PDF]

open access: yesPlants
The maintenance of the root stem cell niche identity in Arabidopsis relies on the delicate balance of reactive oxygen species (ROS) levels in root tips; however, the intricate molecular mechanisms governing ROS homeostasis within the root stem cell niche
Qianqian Yu   +5 more
doaj   +3 more sources

Structures of Fission Yeast Inositol Pyrophosphate Kinase Asp1 in Ligand-Free, Substrate-Bound, and Product-Bound States.

open access: yesMBio, 2022
Expression of the fission yeast Schizosaccharomyces pombe phosphate regulon is sensitive to the intracellular level of the inositol pyrophosphate signaling molecule 1,5-IP8.
Stewart Shuman   +2 more
exaly   +4 more sources

Transporter-Driven Glycerophosphocholine (GPC) Toxicity Is Conserved from Fission Yeast to Budding Yeast: Roles for Inositol Pyrophosphates and Gde1 Regulation in Fission Yeast [PDF]

open access: yesBiomolecules
Glycerophosphocholine (GPC) and glycerophosphoinositol (GPI) are phospholipid metabolites generated by phospholipase-mediated deacylation. In budding yeast, they enter cells via the Git1 permease; in fission yeast, the homolog is Tgp1.
Victoria Lee Hrach   +8 more
doaj   +2 more sources

Structural and biochemical differences between non-catalytic and catalytic antibodies [PDF]

open access: yesmAbs
A conventional antibody can be converted into its catalytic counterparts by deleting Pro95 in the CDR-3 of human and mice antibody light chains, as previously reported.
Taizo Uda   +10 more
doaj   +2 more sources

Evaluation of glucosinolate content and genotype-by-year interaction in Camelina sativa (L.) Crantz using AMMI analysis along with two novel stability indices [PDF]

open access: yesBMC Plant Biology
Background The purpose of this study was to examine how year, genotype, and their interaction affect agromorpho/phenological and quality variables in a population of 15 newly created doubled-haploid winter camelina lines.
Fariborz Noormohammadi   +3 more
doaj   +2 more sources

Cryptic diversity in Astyanax (Characiformes: Acestrorhamphidae) from the Magdalena basin, Colombia: Insights from molecular and morphometric evidence. [PDF]

open access: yesPLoS ONE
Astyanax Baird & Girard, 1854 is a widely distributed and species-rich genus of Acestrorhamphidae, whose abundant populations in Neotropical basins play a crucial ecological role at the trophic level.
Edna Judith Márquez   +3 more
doaj   +2 more sources

Origin of purple asparagus cultivar ‘Pacific Purple’ based on the sequence of sex determination gene [PDF]

open access: yesFrontiers in Plant Science, 2023
Garden asparagus is one of the most important crops worldwide. Since this crop is dioecious and male plants generally have higher yields compared to female plants, several DNA markers for sex identification have been developed for acceleration of ...
Akira Kanno, Nana Hirobe, Lei Zhang
doaj   +2 more sources

Activities and genetic interactions of fission yeast Aps1, a Nudix-type inositol pyrophosphatase and inorganic polyphosphatase [PDF]

open access: yesmBio
Inositol pyrophosphate 1,5-IP8 regulates expression of a fission yeast phosphate homeostasis regulon, comprising phosphate acquisition genes pho1, pho84, and tgp1, via its action as an agonist of precocious termination of transcription of the upstream ...
Shreya Ghosh   +6 more
doaj   +2 more sources

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