Results 21 to 30 of about 2,537 (176)

Triple florigenic signaling in rice promotes stem elongation via transcriptional de-repression. [PDF]

Plant J
Significance Statement Rice florigenic proteins Hd3a, RFT1, and FT‐L1 coordinate reproductive transition with stem elongation through repression of PINE1 expression, independently of floral MADS box proteins, relieving repression of internode growth. PINE1 represses growth by transcriptionally repressing target genes by interacting with TOPLESS‐related
Vicentini G, Bertagnon G, Dobetti F, Giaume F, Cazzaniga F, Baldini A, Bono GA, Maika J, Moore SS, Bignardi A, Simon R, Perrella G, Nagai K, Ashikari M, Fornara F, Brambilla V.   +15 more
europepmc   +2 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates. [PDF]

FEBS Lett
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Rolfes RJ.
europepmc   +2 more sources

Influence of Head-to-Tail Cyclization of Lanmodulin-Inspired Peptides on Lanthanide Affinity and Structure. [PDF]

Chemistry
The influence of head‐to‐tail cyclization, as well as the effect of ring expansion with an additional glycine on lanmodulin‐inspired peptides on the structure and lanthanide (Ln)‐binding behavior was investigated. While the decrease of structural flexibility can indeed increase the Ln affinity and peptide pre‐organization, it does not lead to an ...
Gutenthaler-Tietze SM, Kretzschmar J, Tsushima S, Weis P, Steudtner R, Drobot B, Daumann LJ.   +6 more
europepmc   +2 more sources

Prodomain Processing of Asp1 (BACE2) Is Autocatalytic [PDF]

Journal of Biological Chemistry, 2001
Generation of the amyloid peptide through proteolytic processing of the amyloid precursor protein by beta- and gamma-secretases is central to the etiology of Alzheimer's disease. The highly elusive beta-secretase was recently identified as a transmembrane aspartic proteinase, Asp2 (BACE).
Hussain I, Christie G, Schneider K, Moore SE, Dingwall C   +4 more
openaire   +3 more sources

Activities, substrate specificity, and genetic interactions of fission yeast Siw14, a cysteinyl-phosphatase-type inositol pyrophosphatase

mBio, 2023
Inositol pyrophosphate 1,5-IP8 is a signaling molecule that regulates phosphate and polyphosphate homeostasis in the fission yeast Schizosaccharomyces pombe. 1,5-IP8 levels are dictated by a balance between the Asp1 kinase domain that converts 5-IP7 to 1,
Ana M. Sanchez, Beate Schwer, Nikolaus Jork, Henning J. Jessen, Stewart Shuman   +4 more
doaj   +1 more source

Inositol Pyrophosphate-Controlled Kinetochore Architecture and Mitotic Entry in S. pombe

Journal of Fungi, 2022
Inositol pyrophosphates (IPPs) comprise a specific class of signaling molecules that regulate central biological processes in eukaryotes. The conserved Vip1/PPIP5K family controls intracellular IP8 levels, the highest phosphorylated form of IPPs present ...
Natascha Andrea Kuenzel, Abel R. Alcázar-Román, Adolfo Saiardi, Simon M. Bartsch, Sarune Daunaraviciute, Dorothea Fiedler, Ursula Fleig   +6 more
doaj   +1 more source

Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies. [PDF]

Adv Sci (Weinh)
Inositol (pyro)phosphates represent a vital class of intracellular messengers that govern multiple biological processes. The last decade has experienced a surge of interest in the functions of this class of signaling molecules, primarily due to the introduction of several innovative analytical technologies.
Saiardi A, Lu M, Zhang Y, Shukla A, Ko AA, Jessen HJ.   +5 more
europepmc   +2 more sources

The Vip1 inositol polyphosphate kinase family regulates polarized growth and modulates the microtubule cytoskeleton in fungi. [PDF]

PLoS Genetics, 2014
Microtubules (MTs) are pivotal for numerous eukaryotic processes ranging from cellular morphogenesis, chromosome segregation to intracellular transport. Execution of these tasks requires intricate regulation of MT dynamics.
Jennifer Pöhlmann, Carmen Risse, Constanze Seidel, Thomas Pohlmann, Visnja Jakopec, Eva Walla, Pascal Ramrath, Norio Takeshita, Sebastian Baumann, Michael Feldbrügge, Reinhard Fischer, Ursula Fleig   +11 more
doaj   +1 more source

Cleavage-Polyadenylation Factor Cft1 and SPX Domain Proteins Are Agents of Inositol Pyrophosphate Toxicosis in Fission Yeast

mBio, 2022
Inositol pyrophosphate (IPP) dynamics govern expression of the fission yeast phosphate homeostasis regulon via their effects on lncRNA-mediated transcription interference.
Beate Schwer, Angad Garg, Ana M. Sanchez, Mindy A. Bernstein, Bradley Benjamin, Stewart Shuman   +5 more
doaj   +1 more source

Effect of brown and green seaweeds on diet digestibility, ruminal fermentation patterns and enteric methane emissions using the rumen simulation technique

Frontiers in Animal Science, 2022
Inclusion of the red seaweed Asparagopsis taxiformis as a feed additive, has led to significant reductions in methane (CH4) production from ruminants.
Emily Roskam, Emily Roskam, Stuart F. Kirwan, David A. Kenny, David A. Kenny, Caroline O’Donnell, Vincent O’Flaherty, Maria Hayes, Sinéad M. Waters, Sinéad M. Waters   +9 more
doaj   +1 more source