Results 51 to 60 of about 2,024 (149)

Molecular Docking of Interaction between E-Cadherin Protein and Conformational Structure of Cyclic Peptide ADTC3 (Ac-CADTPC-NH2) Simulated on 20 ns

Jurnal Kimia Sains dan Aplikasi, 2017
Pengobatan penyakit yang menyerang otak sangat sulit dilakukan karena penghantaran molekul obat menuju otak terhalang oleh molekul-molekul blood-brain barrier (BBB).
Atiatul Manna, Marlyn Dian Laksitorini, Dwi Hudiyanti, Parsaoran Siahaan   +3 more
doaj   +1 more source

Auxin apical dominance governed by the OsAsp1-OsTIF1 complex determines distinctive rice caryopses development on different branches.

PLoS Genetics, 2020
In rice (Oryza sativa), caryopses located on proximal secondary branches (CSBs) have smaller grain size and poorer grain filling than those located on apical primary branches (CPBs), greatly limiting grain yield.
Shu Chang, Yixing Chen, Shenghua Jia, Yihao Li, Kun Liu, Zhouhua Lin, Hanmeng Wang, Zhilin Chu, Jin Liu, Chao Xi, Heping Zhao, Shengcheng Han, Yingdian Wang   +12 more
doaj   +1 more source

Genome‐wide exploration of bacterial leaf blight resistance and fine mapping of major resistance gene (Bb13) in upland cotton (Gossypium hirsutum L.)

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Cotton bacterial blight (CBB), caused by Xanthomonas citri subsp. malvacearum (Xcm), continues to pose a significant threat to upland cotton (Gossypium spp.) production across the US Cotton Belt. To elucidate the genetic basis of resistance to race 18 of CBB and identify potential novel resistance sources, we conducted genome‐wide association ...
Spoorti S. Gandhadmath, Fred M. Bourland, S. Anjan Gowda, Navin Shrestha, Don C. Jones, Kaitlyn Bissonnette, Vasu Kuraparthy   +6 more
wiley   +1 more source

Characterizing the Lanthanide‐Binding Tag Grafted at Calmodulin Site 1: Affinity, Selectivity, and Coordination Properties

European Journal of Inorganic Chemistry, Volume 29, Issue 3, January 21, 2026.
Lanthanide affinity and selectivity in proteins remain poorly understood. Engineering calmodulin with a lanthanide‐binding tag at Site 1 boosts affinity from nanomolar (isolated LBTs) to picomolar dissociation constants, comparable to lanmodulin but with distinct selectivity.
Catherine Berthomieu, Manon Martin, Jean Aupiais, Tiffanie Barré, Loïc Daronnat, Jérémy Pansier, Nicolas Brémond, David Lemaire, Atul Thawari, Martin Levier, Laurence Berthon, Sandrine Sauge‐Merle   +11 more
wiley   +1 more source

Evaluation of a New Methylimidazole‐Containing Thiosemicarbazone as a Cu+/Cu2+‐Targeting Ligand in the Context of Alzheimer's Disease

Chemistry – A European Journal, Volume 32, Issue 1, 2 January 2026.
HXE modulates Cu(Aβ) interaction, reducing ROS production and shifting peptide aggregation in the presence of Cu from toxic amorphous aggregates to less harmful fibrillar structures. These findings highlight HXE potential to interfere with Cu‐induced oxidative stress and aggregation pathways relevant to AD.
Barbara Marinho Barbosa, Charlène Esmieu, Antal Galvácsi, Mariana Viana Costa, Adèle Brison, Sonia M. Ladeira, Jade de Oliveira, Csilla Kállay, Christelle Hureau, Nicolás A. Rey   +9 more
wiley   +1 more source

Phase I study of TY-10721 ((Asp1-Ile5) angiotensin II).

Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics, 1990
Angiotensin-II-Induced Hypertension Chemotherapy is an approach to selective enhancement of drug delivery to tumor tissue for increase of chemotherapeutic effects. TY-10721 (TY) is a newly synthesized compound of human type of angiotensin II ([Asp1-Ile5] angiotensin II) by TOA EIYO Ltd.(Tokyo).Along with and after stopping of the continuous infusion of
SATO, Haruhiko, HOSHI, Masahiko, WAKUI, Akira, SUZUKI, Maroh   +3 more
openaire   +2 more sources

Correlation of the biological activity and solution conformation of [Asp1,Ile5]- and [Phe4,Tyr8]angiotensin II. [PDF]

Proceedings of the National Academy of Sciences, 1978
Angiotensin II is known to undergo a reversible conformational transition and a change in potency in rat uterus in vitro with pK approximately 6.5. We have shown by carbon-13 NMR that the conformational transition involves all-trans to partly cis isomerization of the His6-Pro7 peptide bond.
H E, Bleich, R J, Freer, S S, Stafford, R E, Galardy   +3 more
openaire   +2 more sources

Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
The production of recombinant proteins represents a fundamental step in the characterisation of marine invertebrate adhesives and in the development of bio‐inspired glues. The association of these proteins with other components such as ions, proteins, polysaccharides, or polymers enables the fabrication of biomaterials for various healthcare ...
Alessandra Whaite, Emilie Duthoo, Mathilde Lefevre, Elise Hennebert, Patrick Flammang   +4 more
wiley   +1 more source

Influence of Rosmarinic Acid on Zinc(II)–Amyloid Beta Coordination

European Journal of Inorganic Chemistry, Volume 29, Issue 1, January 1, 2026.
NMR and UV–vis investigations identify an Aβ–Zn–RA ternary complex that shifts metal‐mediated equilibria and promotes precipitation. Natural polyphenols such as rosmarinic acid (RA) are gaining attention for their antioxidant, anti‐inflammatory, and neuroprotective properties, attributed in part to their ability to chelate redox‐active metals. While RA'
Arian Kola, Daniela Valensin
wiley   +1 more source

Unusual biota and palynofacies of a Lower Devonian intermontane basin saline lake–playa mudflat ecosystem

Papers in Palaeontology, Volume 12, Issue 1, January/February 2026.
Abstract The Strathpeffer–Struie Lower Devonian LORS (Lower Old Red Sandstone) deposits of the Northern Highlands of Scotland contain the decidedly unusual ‘foetid beds’. These are interpreted as being deposited in a highly saline sulphate lake and associated playa mudflat, which developed in an intermontane basin in the Caledonian Mountains of ...
Charles H. Wellman
wiley   +1 more source