Results 61 to 70 of about 2,537 (176)

Exploring E-cadherin-peptidomimetics interaction using NMR and computational studies.

PLoS Computational Biology, 2019
Cadherins are homophilic cell-cell adhesion molecules whose aberrant expression has often been shown to correlate with different stages of tumor progression.
Monica Civera, Francesca Vasile, Donatella Potenza, Cinzia Colombo, Sara Parente, Chiara Vettraino, Tommaso Prosdocimi, Emilio Parisini, Laura Belvisi   +8 more
doaj   +1 more source

Interaction Studies Between Cyclic Peptide ADT-C3 (Ac-CADTPC-NH2) with E-Cadherin Protein using the Molecular Docking Method Simulated on 120ns

Jurnal Kimia Sains dan Aplikasi, 2018
The treatment of diseases that attack the brain is very difficult, because the delivery of drug molecules to the brain is often hindered by the blood-brain barrier (BBB). So that the drug delivery is not right on the target cell.
Parsaoran Siahaan, Vivitri Dewi Prasasty, Atiatul Manna, Dwi Hudiyanti   +3 more
doaj   +1 more source

Structural and phylogenetic analysis of a conserved actinobacteria-specific protein (ASP1; SCO1997) from Streptomyces coelicolor [PDF]

BMC Structural Biology, 2009
AbstractBackgroundThe Actinobacteria phylum represents one of the largest and most diverse groups of bacteria, encompassing many important and well-characterized organisms includingStreptomyces, Bifidobacterium, CorynebacteriumandMycobacterium. Members of this phylum are remarkably diverse in terms of life cycle, morphology, physiology and ecology ...
Gao, Beile, Sugiman-Marangos, Seiji, Junop, Murray S, Gupta, Radhey S   +3 more
openaire   +2 more sources

Comprehensive transcriptome and metabolome profiling reveal metabolic mechanisms of Nitraria sibirica Pall. to salt stress

Scientific Reports, 2021
Nitraria sibirica Pall., a typical halophyte that can survive under extreme drought conditions and in saline-alkali environments, exhibits strong salt tolerance and environmental adaptability.
Huanyong Li, Xiaoqian Tang, Xiuyan Yang, Huaxin Zhang   +3 more
doaj   +1 more source

Nitrogen Status Rewires Transcriptional Regulation of Dhurrin, a Dual‐Purpose Defense Metabolite in Sorghum bicolor

Plant Direct, Volume 10, Issue 8, August 2026.
ABSTRACT Dhurrin, a cyanogenic glucoside, plays an important role in Sorghum bicolor physiology and defense. The concentration of dhurrin in sorghum is influenced by both nitrogen status and stage of plant organ development. While nitrogen resupply activates the expression of genes for dhurrin biosynthesis, the molecular mechanisms underlying this ...
Alicia A. Quinn, Brian A. McKinley, Cecilia K. Blomstedt, John E. Mullet, Roslyn M. Gleadow   +4 more
wiley   +1 more source

Auxin apical dominance governed by the OsAsp1-OsTIF1 complex determines distinctive rice caryopses development on different branches.

PLoS Genetics, 2020
In rice (Oryza sativa), caryopses located on proximal secondary branches (CSBs) have smaller grain size and poorer grain filling than those located on apical primary branches (CPBs), greatly limiting grain yield.
Shu Chang, Yixing Chen, Shenghua Jia, Yihao Li, Kun Liu, Zhouhua Lin, Hanmeng Wang, Zhilin Chu, Jin Liu, Chao Xi, Heping Zhao, Shengcheng Han, Yingdian Wang   +12 more
doaj   +1 more source

Improving cytosolic aspartate biosynthesis increases glucoamylase production in Aspergillus niger under oxygen limitation

Microbial Cell Factories, 2020
Background Glucoamylase is one of the most industrially applied enzymes, produced by Aspergillus species, like Aspergillus niger. Compared to the traditional ways of process optimization, the metabolic engineering strategies to improve glucoamylase ...
Weiqiang Cao, Guan Wang, Hongzhong Lu, Liming Ouyang, Ju Chu, Yufei Sui, Yingping Zhuang   +6 more
doaj   +1 more source

Specific receptors for des-Asp1-angiotensin II (("angiotensin III") in rat adrenals. [PDF]

Proceedings of the National Academy of Sciences, 1977
The specific binding of angiotensin II and des-Asp1-angiotensin II ("angiotensin III") III") to rat adrenals was studied with the use of the tritiated peptides. The binding sites having maximal affinity for angiotensin II were characterized by an equilibrium dissociation constant of 3.3 to 5.2 X 10(-9) M. Angiotensin III was able to interact with these
M A, Devynck, M G, Pernollet, P G, Matthews, M C, Khosla, F M, Bumpus, P, Meyer   +5 more
openaire   +2 more sources

Hydrogen bonds occupancy in ASP1 at different pH conditions.

, 2014
Hydrogen bonds occupancy in ASP1 at different pH conditions.
Lei Han (150108), Xu Cui (261214), Jinpu Yu (283737), Yong-Jun Zhang (144160), Ziding Zhang (145526), Ming S. Liu (150121), Long Zhang (315279)   +6 more
core   +1 more source

Molecular Docking of Interaction between E-Cadherin Protein and Conformational Structure of Cyclic Peptide ADTC3 (Ac-CADTPC-NH2) Simulated on 20 ns

Jurnal Kimia Sains dan Aplikasi, 2017
Pengobatan penyakit yang menyerang otak sangat sulit dilakukan karena penghantaran molekul obat menuju otak terhalang oleh molekul-molekul blood-brain barrier (BBB).
Atiatul Manna, Marlyn Dian Laksitorini, Dwi Hudiyanti, Parsaoran Siahaan   +3 more
doaj   +1 more source