Results 81 to 90 of about 7,135 (185)

Tuning hardness in calcite by incorporation of amino acids [PDF]

open access: yes, 2016
Structural biominerals are inorganic/organic composites that exhibit remarkable mechanical properties. However, the structure–property relationships of even the simplest building unit—mineral single crystals containing embedded macromolecules—remain ...
AE Stephenson   +64 more
core   +5 more sources

Structure of amyloid-β (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface. [PDF]

open access: yes, 2019
Amyloid-β (Aβ) harbors numerous posttranslational modifications (PTMs) that may affect Alzheimer's disease (AD) pathogenesis. Here we present the 1.1 Å resolution MicroED structure of an Aβ 20-34 fibril with and without the disease-associated PTM, L ...
Boyer, David R   +8 more
core  

Asp1, a Conserved 1/3 Inositol Polyphosphate Kinase, Regulates the Dimorphic Switch inSchizosaccharomyces pombe [PDF]

open access: yesMolecular and Cellular Biology, 2010
The ability to undergo dramatic morphological changes in response to extrinsic cues is conserved in fungi. We have used the model yeast Schizosaccharomyces pombe to determine which intracellular signal regulates the dimorphic switch from the single-cell yeast form to the filamentous invasive growth form. The S.
Jennifer, Pöhlmann, Ursula, Fleig
openaire   +2 more sources

Spontaneous Isomerization of Long-Lived Proteins Provides a Molecular Mechanism for the Lysosomal Failure Observed in Alzheimer's Disease. [PDF]

open access: yes, 2019
Proteinaceous aggregation is a well-known observable in Alzheimer's disease (AD), but failure and storage of lysosomal bodies within neurons is equally ubiquitous and actually precedes bulk accumulation of extracellular amyloid plaque. In fact, AD shares
Augello, Catherine   +9 more
core   +1 more source

SP3 and DEP1 Orchestrate Panicle Architecture by Jointly Regulating APO2 Expression in Rice

open access: yesAdvanced Science, Volume 12, Issue 44, November 27, 2025.
The transcription factor SP3 enhances inflorescence meristem activity and interacts with the cysteine‐rich domain of DEP1. This interaction alters DEP1's subcellular localization between the plasma membrane and nucleus, and suppresses SP3‐mediated transcriptional activation of APO2.
Yuexin Liu   +11 more
wiley   +1 more source

Contribution of Amino Acids in Cereal Grain Products to Precision Feed Formulation for Tambaqui (Colossoma macropomum) Using a Digestibility Approach

open access: yesJournal of Animal Physiology and Animal Nutrition, Volume 109, Issue 6, Page 1264-1272, November 2025.
ABSTRACT Although cereal grain products have low protein content, they can contribute up to 25% of total protein in low‐trophic level/omnivorous fish diets. Thus, understanding the amino acid contribution of these ingredients becomes crucial for meeting the dietary requirements of omnivorous fish.
Danilo C. Proença   +4 more
wiley   +1 more source

Genomic Characterisation of Limosilactobacillus fermentum CRL2085 Unveiling Probiotic Traits for Application in Cattle Feed

open access: yesEnvironmental Microbiology Reports, Volume 17, Issue 5, October 2025.
A comprehensive genomic and phenotypic analysis of Limosilactobacillus fermentum CRL2085 revealed key probiotic and nutritional traits supporting its safe application in cattle feed. The strain harbors genes for stress tolerance, adhesion, exopolysaccharide production, and B‐vitamin biosynthesis, and efficiently metabolizes plant‐derived carbohydrates,
Cecilia M. Aristimuño Ficoseco   +9 more
wiley   +1 more source

An eLearning Standard Approach for Supporting PBL in Computer Engineering [PDF]

open access: yes, 2009
Problem-based learning (PBL) has proved to be a highly successful pedagogical model in many fields, although it is not that common in computer engineering. PBL goes beyond the typical teaching methodology by promoting student interaction.
Díaz del Río, Fernando   +3 more
core   +1 more source

Risks of bromoform by adding seaweed of the genus Asparagopsis to feed for ruminants

open access: yesFood Risk Assess Europe, Volume 3, Issue 4, October 2025.
Abstract Aim Livestock farming is a large contributor to methane emission, a strong greenhouse gas. In order to achieve climate goals methods to reduce methane emission are being explored. Some promising results are obtained by adding Asparagopsis to feed for ruminants. Asparagopsis is a red seaweed which contains high levels of bromoform.
J.W.H. Biesterbos   +2 more
wiley   +1 more source

Neighboring Segments Control on Earthquake Recurrence Patterns: Insights From Scaled Seismotectonic Models

open access: yesGeophysical Research Letters, Volume 52, Issue 18, 28 September 2025.
Abstract Understanding the factors that influence the spatial and temporal rupture history of large subduction earthquakes is essential for seismic hazard assessment. In this study, we focus on one candidate: the interaction between neighboring asperities of different sizes and normal loads.
Elvira Latypova   +5 more
wiley   +1 more source

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