Results 81 to 90 of about 2,537 (176)

Evaluation of a New Methylimidazole‐Containing Thiosemicarbazone as a Cu+/Cu2+‐Targeting Ligand in the Context of Alzheimer's Disease

Chemistry – A European Journal, Volume 32, Issue 1, 2 January 2026.
HXE modulates Cu(Aβ) interaction, reducing ROS production and shifting peptide aggregation in the presence of Cu from toxic amorphous aggregates to less harmful fibrillar structures. These findings highlight HXE potential to interfere with Cu‐induced oxidative stress and aggregation pathways relevant to AD.
Barbara Marinho Barbosa, Charlène Esmieu, Antal Galvácsi, Mariana Viana Costa, Adèle Brison, Sonia M. Ladeira, Jade de Oliveira, Csilla Kállay, Christelle Hureau, Nicolás A. Rey   +9 more
wiley   +1 more source

Competitive inhibition of Asp1-β-amide-Val5-angiotensin II by Sar1-Ile5-Ile8-angiotensin II in cat isolated cardiac muscle and coronary vessels

, 1974
Interaction of Asp1-β-amide-Val5-angiotensin II with the 8-substituted analogue of Asp1-Ile5-angiotensin II, Sar1-Ile5-Ile8-angiotensin II, has been examined on the isolated perfused heart and isolated papillary muscle of the cat.
M M Hall, F M Bumpus, R K Türker
core   +1 more source

Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
The production of recombinant proteins represents a fundamental step in the characterisation of marine invertebrate adhesives and in the development of bio‐inspired glues. The association of these proteins with other components such as ions, proteins, polysaccharides, or polymers enables the fabrication of biomaterials for various healthcare ...
Alessandra Whaite, Emilie Duthoo, Mathilde Lefevre, Elise Hennebert, Patrick Flammang   +4 more
wiley   +1 more source

Influence of Rosmarinic Acid on Zinc(II)–Amyloid Beta Coordination

European Journal of Inorganic Chemistry, Volume 29, Issue 1, January 1, 2026.
NMR and UV–vis investigations identify an Aβ–Zn–RA ternary complex that shifts metal‐mediated equilibria and promotes precipitation. Natural polyphenols such as rosmarinic acid (RA) are gaining attention for their antioxidant, anti‐inflammatory, and neuroprotective properties, attributed in part to their ability to chelate redox‐active metals. While RA'
Arian Kola, Daniela Valensin
wiley   +1 more source

Asp1 from Schizosaccharomyces pombe Binds a [2Fe-2S]²⁺ Cluster Which Inhibits Inositol Pyrophosphate 1‑Phosphatase Activity

, 2015
Iron–sulfur (Fe–S) clusters are widely distributed protein cofactors that are vital to cellular biochemistry and the maintenance of bioenergetic homeostasis, but to our knowledge, they have never been identified in any phosphatase.
Huanchen Wang (1500046), Vasudha S. Nair (1500049), Michael K. Johnson (1288806), Stephen B. Shears (528105), Henning J. Jessen (1500052), Ashley A. Holland (1500043), Samanta Capolicchio (1500040)   +6 more
core   +1 more source

Unusual biota and palynofacies of a Lower Devonian intermontane basin saline lake–playa mudflat ecosystem

Papers in Palaeontology, Volume 12, Issue 1, January/February 2026.
Abstract The Strathpeffer–Struie Lower Devonian LORS (Lower Old Red Sandstone) deposits of the Northern Highlands of Scotland contain the decidedly unusual ‘foetid beds’. These are interpreted as being deposited in a highly saline sulphate lake and associated playa mudflat, which developed in an intermontane basin in the Caledonian Mountains of ...
Charles H. Wellman
wiley   +1 more source

The evolution of minimum distance between side chain beads of Asp1 (or residues Asp1 mutated to) and Lys (or residue Lys mutated to) (black), Asp2 (or residues Asp2 mutated to) and Lys (or residue Lys mutated to) (red) of all four mutants of the trimer: DAP12-NKG2C-D50L, DAP12-NKG2C-D50N, DAP12-K52L-DAP12, and T54A-NKG2C-T54A.

, 2014
The evolution of minimum distance between side chain beads of Asp1 (or residues Asp1 mutated to) and Lys (or residue Lys mutated to) (black), Asp2 (or residues Asp2 mutated to) and Lys (or residue Lys mutated to) (red) of all four mutants of the trimer ...
Cheng-Dong Li (620106), Peng Wei (46487), Lida Xu (326852), Fu-De Sun (620107), Long Chen (315739), Tianwei Tan (457804), Shi-Zhong Luo (620108)   +6 more
core   +1 more source

Unraveling the sequence of cytosolic reactions in the export of GspB adhesin from Streptococcus gordonii [PDF]

, 2018
Many pathogenic bacteria, including Streptococcus gordonii, possess a pathway for the cellular export of a single serine-rich-repeat protein that mediates the adhesion of bacteria to host cells and the extracellular matrix.
Asif Shajahan, Seepersaud, Ravin, Barbara A. Bensing, Mi, Wei, Rapoport, Tom A, Yu Chen, Liao, Maofu, Philip D. Jeffrey, Bensing, Barbara A, Shajahan, Asif, Chen, Yu, Sullam, Paul M, Ravin Seepersaud, Maofu Liao, Tom A. Rapoport, Paul M. Sullam, Wei Mi, Sonon, Roberto N, Roberto N. Sonon, Parastoo Azadi, Jeffrey, Philip D, Azadi, Parastoo   +21 more
core   +1 more source

Reversible SUMOylation of FHY1 Regulates Phytochrome A Signaling in Arabidopsis

, 2020
In response to far-red light (FR), FAR-RED ELONGATED HYPOCOTYL 1 (FHY1) transports the photoactivated phytochrome A (phyA), the primary FR photoreceptor, into the nucleus, where it initiates FR signaling in plants.
Qu, Gao-Ping, Li, Hong, Liu, Yu, Lin, Rongcheng, Jin, Jing Bo, Lin, Xiao-Li, Song, Hang-Lin, Hu, Zi-Liang, Li, Jigang, Jin, Yin Hua, Kong, Xiangxiong, Kim, Dae Heon   +11 more
core   +1 more source

Action of natural angiotensin II and synthetic analogues on strips of rabbit aorta

, 1964
The pressor activity of pure natural asp1ileu5-angiotensin II, and synthetic asparginyl1-val5, asp1-val5, asp1-ileu5, and ß-asp1-val5-angiotensin II was determined in a nephrectomized pithed cat.
Oscar M. Helmer
core   +1 more source