Results 61 to 70 of about 14,723 (146)
Micro/Nanorobot for Drug Delivery—A Review of Material Selections
This review explores material strategies for biomedical micro/nanorobots, emphasizing their roles in propulsion, navigation, drug delivery, and biodegradability. It highlights advancements in metallic, polymeric, and hybrid materials, while addressing clinical translation challenges such as toxicity, immune response, and manufacturability.
Xiaozhuo Wu, Bingyun Li, Malcolm Xing
wiley +1 more source
Optimization of asparaginase production from Zymomonas mobilis by continuous fermentation
Asparaginase is an enzyme used in clinical treatments as a chemotherapeutic agent and in food technology to prevent acrylamide formation in fried and baked foods.
Francieli Bortoluzzi Menegat +3 more
doaj +1 more source
Analysis of adults type b‐acute lymphoblastic leukemia in ecuador. This demonstrates inferior response and survival outcomes for b‐all in Ecuador and can serve as a reference to Latin America countries due to geographic, racial and socioeconomic similarities.
Brenner Sabando +12 more
wiley +1 more source
Considerations for Menstrual Suppression in Patients With Hematologic Malignancies
ABSTRACT Patients who menstruate during treatment for hematologic malignancies have a higher risk of heavy vaginal bleeding due to thrombocytopenia caused by malignancy and myelosuppressive chemotherapy. Heavy menstrual bleeding is associated with significant morbidity in this patient population, and menstrual suppression is a standard of supportive ...
Sahaana Veeravalli +3 more
wiley +1 more source
Kunyit putih (Curcuma mangga Val.) merupakan salah satu sumber L-asparaginase yang berpotensi sebagai bioaktif antikanker. Tujuan penelitian ini adalah untuk menentukan nilai LC50 dan potensi antikanker enzim L-asparaginase dari kunyit putih pada kultur ...
Citrawati Octavia Suprobo +2 more
doaj +1 more source
Armed with unique structural and functional properties, elastin‐like polypeptides attract their attentions as programmable materials in biomedical applications, including fusion tags for protein and nucleic acid purification; nanocarriers for protein, chemotherapeutics, and imaging agent delivery; hydrogels for tissue regeneration, 3D model ...
Yang Yuan +9 more
wiley +1 more source
Production of L-asparaginase by filamentous fungi
L-asparaginase production was investigated in the filamentous fungi Aspergillus tamarii and Aspergillus terreus. The fungi were cultivated in medium containing different nitrogen sources. A. terreus showed the highest L-asparaginase (activity) production
Maria Inez de Moura Sarquis +3 more
doaj +1 more source
Phase 1 Dose Escalation of Single‐Agent Mechlorethamine in Dogs With Lymphoma
ABSTRACT Mechlorethamine is commonly prescribed to dogs at 3 mg/m2. The minimal toxicity observed indicates that higher doses of mechlorethamine are likely tolerable. The primary objective of this study was to determine the maximally tolerated dose (MTD) of mechlorethamine in dogs with lymphoma.
Laura E. Chadsey +2 more
wiley +1 more source
Objective: To explore the anti-proliferative activity of purified l-asparaginase from Aspergillus oryzae CCT 3940 (A. oryzae). Methods: l-asparaginase was produced by submerged fermentation and purified to electrophoresis homogeneity by ionic exchanged ...
Fernanda Furlan Gonçalves Dias +3 more
doaj +1 more source
L-asparaginase catalyzes the hydrolysis of asparagine into ammonia and aspartate. It has been used in chemotherapy for patients with acute lymphoblastic leukemia. L-asparaginase presents in animal, plant and microorganism.
Ruby Setiawan, Dinar Rahmi Larasati
doaj +1 more source

