Results 61 to 70 of about 14,723 (146)

Micro/Nanorobot for Drug Delivery—A Review of Material Selections

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 3, March 2026.
This review explores material strategies for biomedical micro/nanorobots, emphasizing their roles in propulsion, navigation, drug delivery, and biodegradability. It highlights advancements in metallic, polymeric, and hybrid materials, while addressing clinical translation challenges such as toxicity, immune response, and manufacturability.
Xiaozhuo Wu, Bingyun Li, Malcolm Xing
wiley   +1 more source

Optimization of asparaginase production from Zymomonas mobilis by continuous fermentation

open access: yesActa Scientiarum: Biological Sciences, 2016
Asparaginase is an enzyme used in clinical treatments as a chemotherapeutic agent and in food technology to prevent acrylamide formation in fried and baked foods.
Francieli Bortoluzzi Menegat   +3 more
doaj   +1 more source

A Multicenter Survival Analysis of Adults Type B‐Acute Lymphoblastic Leukemia in Ecuador. A Retrospective Study of the Real World

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
Analysis of adults type b‐acute lymphoblastic leukemia in ecuador. This demonstrates inferior response and survival outcomes for b‐all in Ecuador and can serve as a reference to Latin America countries due to geographic, racial and socioeconomic similarities.
Brenner Sabando   +12 more
wiley   +1 more source

Considerations for Menstrual Suppression in Patients With Hematologic Malignancies

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 3, March 2026.
ABSTRACT Patients who menstruate during treatment for hematologic malignancies have a higher risk of heavy vaginal bleeding due to thrombocytopenia caused by malignancy and myelosuppressive chemotherapy. Heavy menstrual bleeding is associated with significant morbidity in this patient population, and menstrual suppression is a standard of supportive ...
Sahaana Veeravalli   +3 more
wiley   +1 more source

Uji Antikanker Isolat Bioaktif L-Asparaginase dari Kunyit Putih (Curcuma mangga Val.) terhadap Sel Kanker Serviks

open access: yesJurnal Kimia Sains dan Aplikasi, 2011
Kunyit putih (Curcuma mangga Val.) merupakan salah satu sumber L-asparaginase yang berpotensi sebagai bioaktif antikanker. Tujuan penelitian ini adalah untuk menentukan nilai LC50 dan potensi antikanker enzim L-asparaginase dari kunyit putih pada kultur ...
Citrawati Octavia Suprobo   +2 more
doaj   +1 more source

Engineered Elastin‐Like Polypeptides: Intelligent Self‐Assembling Platforms for Biomedical Application

open access: yesSmall Structures, Volume 7, Issue 3, March 2026.
Armed with unique structural and functional properties, elastin‐like polypeptides attract their attentions as programmable materials in biomedical applications, including fusion tags for protein and nucleic acid purification; nanocarriers for protein, chemotherapeutics, and imaging agent delivery; hydrogels for tissue regeneration, 3D model ...
Yang Yuan   +9 more
wiley   +1 more source

Production of L-asparaginase by filamentous fungi

open access: yesMemorias do Instituto Oswaldo Cruz, 2004
L-asparaginase production was investigated in the filamentous fungi Aspergillus tamarii and Aspergillus terreus. The fungi were cultivated in medium containing different nitrogen sources. A. terreus showed the highest L-asparaginase (activity) production
Maria Inez de Moura Sarquis   +3 more
doaj   +1 more source

Phase 1 Dose Escalation of Single‐Agent Mechlorethamine in Dogs With Lymphoma

open access: yesVeterinary and Comparative Oncology, Volume 24, Issue 1, Page 51-57, March 2026.
ABSTRACT Mechlorethamine is commonly prescribed to dogs at 3 mg/m2. The minimal toxicity observed indicates that higher doses of mechlorethamine are likely tolerable. The primary objective of this study was to determine the maximally tolerated dose (MTD) of mechlorethamine in dogs with lymphoma.
Laura E. Chadsey   +2 more
wiley   +1 more source

Purification, characterization and antiproliferative activity of l-asparaginase from Aspergillus oryzae CCT 3940 with no glutaminase activity

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2016
Objective: To explore the anti-proliferative activity of purified l-asparaginase from Aspergillus oryzae CCT 3940 (A. oryzae). Methods: l-asparaginase was produced by submerged fermentation and purified to electrophoresis homogeneity by ionic exchanged ...
Fernanda Furlan Gonçalves Dias   +3 more
doaj   +1 more source

Screening of Bacteria Producing Asparaginase Free of Glutaminase and Urease from Hot Springs in West Sulawesi

open access: yesBiosaintifika: Journal of Biology & Biology Education, 2019
L-asparaginase catalyzes the hydrolysis of asparagine into ammonia and aspartate. It has been used in chemotherapy for patients with acute lymphoblastic leukemia. L-asparaginase presents in animal, plant and microorganism.
Ruby Setiawan, Dinar Rahmi Larasati
doaj   +1 more source

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