Results 21 to 30 of about 181,665 (333)
Background: The occurrence of Cutaneous Adverse Drug Reactions (CADRs) is relatively rare but can be fatal when causing organ failure, especially in the liver. The supporting examinations to determine liver injury are aspartate aminotransferase (AST) and
Dyah Ayu Mira Oktarina+2 more
doaj +1 more source
Photoinactivation of Aspartate Aminotransferase
Abstract The cofactor pyridoxal 5'-phosphate bound through an aldimine linkage to lysine residues of the enzyme aspartate aminotransferase is very stable to irradiation with light of 420 nm. The catalytic function of the enzyme exposed to light absorbed by the cofactor remains unaffected, indicating that pyridoxal 5'-phosphate is not an efficient ...
Noranna Burridge, Jorge E. Churchich
openaire +3 more sources
MACRO-ASPARTATE AMINOTRANSFERASE
Measurement of serum enzyme activity is one of the most common laboratory tests. Increased activity may be caused by abnormal enzymes with a high molecular mass, the so-called macroenzymes. Macroenzymes may be seen in healthy subjects, but can also be related to disease. Macro-aspartate aminotransferase (macro-AST) is a macroenzyme that results from an
L. I. Plotnikova+3 more
openaire +2 more sources
Effects of temperature on the steady-state kinetics and measurement of aspartate aminotransferases.
We examined the effects of temperature on the activity and steady-state kinetics of aspartate aminotransferase (EC 2.6.1.1), using purified human soluble (s-AspAT) and mitochondrial (m-AspAT) isoenzymes, human serum, and porcine s-AspAT.
R. Rej, R. Vanderlinde
semanticscholar +1 more source
Background The prognostic values of preoperative aspartate aminotransferase (AST), monocyte-to-lymphocyte ratio (MLR), AST·MLR index (AMLRI) and operation injury condition in patients with colorectal cancer liver metastases (CRLM) remains unclear.
Qichen Chen+6 more
doaj +1 more source
Principles of reptile treatment are significantly different from the drug therapy for mammals and birds, which is primarily due to anatomical and physiological peculiarities of reptiles.
R. S. Dankovych, V. I. Chuliuk
doaj +1 more source
Targeting aspartate aminotransferase in breast cancer [PDF]
Abstract Introduction Glycolysis is increased in breast adenocarcinoma cells relative to adjacent normal cells in order to produce the ATP and anabolic precursors required for survival, growth and invasion.
Andrew N. Lane+8 more
openaire +3 more sources
Serum Aminotransferase Level in Rhabdomyolysis according to Concurrent Liver Disease
Background/Aims: The serum aminotransferase level is usually elevated in rhabdomyolysis, and these enzymes originate from the skeletal muscle. On the other hand, there is limited data showing whether the degree of elevation of these enzymes differs ...
Kyeong Min Jo+8 more
doaj +1 more source
Preventive effects of Prangos ferulacea (L.) Lindle on liver damage of diabetic rats induced by alloxan [PDF]
Objectives: Diabetes mellitus is associated with biochemical, physiological and pathological alterations in the liver. The aim of this study was to investigate the effects of hydroalcoholic extract of Prangos ferulacea (L.) Lindle (P.f) on changes in ...
Farah Farokhi+3 more
doaj
Hepato-Protective Effects of Silymarin and Coffee in Rats
Objective: To compare the effects of silymarin and coffee on liver enzymes in acetaminophen-induced hepatotoxicity in rats. Study Design: Experimental-randomized control study.
Sidra Mumal, Akbar Waheed, Abdul Azeem, Hira Waqas Cheema, Fakhra Noureen, Abeera Zainab
doaj