Selective permeability of rat liver mitochondria to purified aspartate aminotransferases in vitro.
Biochemical Journal, 1977 1. A method was devised to allow determination of intramitochondrial aspartate amino-transferase activity in suspensions of intact mitochondria. 2.
E. Marra +3 more
semanticscholar +1 more source
Inhibition of Alanine and Aspartate Aminotransferases by B-Nitropropionic Acid
Journal of High Institute of Public Health, 2007 The inhibition of serum alanine and aspartate aminotransferases (SALT and SAST) by b nitropropionic acid (bNPA), toxic metabolite of some fungi higher plants) in vitro was studied.
Hassan M.Y. Osman
doaj +1 more source
A Biochemical Logic Approach to Biomarker-Activated Drug Release [PDF]
J. Mater. Chem. 22, 19709-19717 (2012), 2013 The present study aims at integrating drug-releasing materials with signal-processing biocomputing systems. Enzymes alanine transaminase (ALT) and aspartate transaminase (AST)---biomarkers for liver injury---were logically processed by a biocatalytic cascade realizing Boolean AND gate. Citrate produced in the system was used to trigger a drug-mimicking
arxiv +1 more source
Coupling enhanced sampling of the apo-receptor with template-based ligand conformers selection: Performance in pose prediction in the D3R-GC4 [PDF]
Journal of Computer-Aided Molecular Design 34, 149-162 (2020), 2020 We report the performance of our newly introduced Ensemble Docking with Enhanced sampling of pocket Shape (EDES) protocol coupled to a template-based algorithm to generate near-native ligand conformations in the 2019 iteration of the Grand Challenge organized by the D3R consortium.
arxiv +1 more source
Effects of Potassium Iodide on Aspartate Aminotransferase [PDF]
European Journal of Biochemistry, 1974 The absorption spectrum of the phosphopyridoxal form of the enzyme, aspartate aminotransferase, can be perturbed by the anion iodide over a wide range of pH values.The binding of this anion to the catalytic site of the enzyme brings about a decrease in the absorption at 360 nm and a concomitant increase in the absorption band centered at 430 nm ...
Jorge E. Churchich, Noranna Burridge
openaire +3 more sources
Robust reference intervals for Liver function test (LFT) analytes in newborns and infants [PDF]
, 2012 BACKGROUND: Reference intervals (RIs) are ranges of upper and lower limits of a given analyte which are used for a laboratory test to determine whether a disease is present or absent or to know if the patient is at risk for future disease states.
Mahilet Yigeremu +6 more
core +1 more source
Energetics of ion competition in the DEKA selectivity filter of neuronal sodium channels [PDF]
Condens. Matter Phys., 2015, vol. 18, No. 1, 13601, 2015 The energetics of ionic selectivity in the neuronal sodium channels is studied. A simple model constructed for the selectivity filter of the channel is used. The selectivity filter of this channel type contains aspartate (D), glutamate (E), lysine (K), and alanine (A) residues (the DEKA locus).
arxiv +1 more source
Serum γ-glutamyltransferase, alanine aminotransferase and aspartate aminotransferase activity in healthy blood donor of different ethnic groups in Gorgan [PDF]
, 2016 Introduction: Measure of liver enzymes may help to increase safety of blood donation for both blood donor and recipient. Determination of liver enzymes may prepare valuable clinical information.
Marjani, A. +2 more
core +1 more source
Pretreatment of hepatetctomized rats with Coleus forskohlii did not interfere with the course of hepatic hyperplasia [PDF]
Acta Cirúrgica Brasileira, 2019 Purpose Coleus forskohlii Briq., a medicinal plant originally from India, has been indicated against heart disease, expiratory disorders, convulsions, and hepatic changes, among others.
Pedro Paulo Barros +3 more
doaj +1 more source
Immunoglobulin-complexed aspartate aminotransferase.
Clinical Chemistry, 1983 Abstract We report two cases of unexplained, isolated, persistently increased aspartate aminotransferase activity in serum. In the first patient, this lasted for 10 years and prompted multiple hospitalizations and medical/surgical consultations.
N. I. Weidner +4 more
openaire +3 more sources