Results 51 to 60 of about 181,665 (333)
A galactose‐modified supramolecular near‐infrared (NIR) glycoprobe, TCF‐FBN@Gal‐BSA, enables targeted delivery to the liver through the asialoglycoprotein receptor (ASGPR) and facilitates liver‐targeting fluorescence visualization of lipid droplets (LDs) in metabolic dysfunction‐associated steatotic liver disease (MASLD) mice.
Han‐Min Wang+12 more
wiley +1 more source
Specificity of aspartate aminotransferases from leguminous plants for 4-substituted glutamic acids.
Aspartate aminotransferase (glutamate-oxalacetate transaminase) was partially purified from extracts of germinating seeds of peanut (Arachis hypogaea), honey locust (Gleditsia triacanthos), soybean (Glycine max), and Sophora japonica.
H. C. Winter, E. E. Dekker
semanticscholar +1 more source
A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao+8 more
wiley +1 more source
Objetivou-se determinar o perfil da aspartato aminotransferase e alanina aminotransferase e a biometria do fígado de codornas poedeiras (Coturnix coturnix japonica) de 1 a 25 dias de idade.
Anderson de Almeida Barbosa+5 more
doaj +1 more source
Identification of high death risk coronavirus disease-19 patients using blood tests
Background: The coronavirus disease (COVID-19) pandemic has made a great impact on health-care services. The prognosis of the severity of the disease help reduces mortality by prioritizing the allocation of hospital resources.
Elaheh Zadeh Hosseingholi+3 more
doaj +1 more source
Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh+3 more
wiley +1 more source
Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson+12 more
wiley +1 more source
Mitochondrial aspartate aminotransferase in nonalcoholic cirrhosis
G Cadiot+5 more
openalex +4 more sources
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang+9 more
wiley +1 more source
Background: Carbon tetrachloride (CCl4) as an organic solvent causes symptoms of acute and chronic liver injury, including necrosis, fat changes, liver cancer, and cirrhosis.
Mohammad Shokrzadeh+4 more
doaj