Results 101 to 110 of about 5,196,013 (375)

Aspartic Acid Decarboxylase in Bacteria.

open access: yesExperimental Biology and Medicine, 1950
SummaryOf 16 strains of microorganisms studied, 7 exhibited positive aspartic acid decarboxylase activity. employing Rh. trijolii this enzyme was found to be stable to vacuum drying, and active cell-free juices could be prepared.
Walter E. David, Herman C. Lichstein
openaire   +2 more sources

Feline hypersomatotropism and acromegaly tumorigenesis: a potential role for the AIP gene [PDF]

open access: yes, 2017
Acromegaly in humans is usually sporadic, however up to 20% of familial isolated pituitary adenomas are caused by germline sequence variants of the aryl-hydrocarbon-receptor interacting protein (AIP) gene.
Catchpole, B   +5 more
core   +1 more source

Enhancing the Protein Stability of an Anticancer VHH‐Fc Heavy Chain Antibody through Computational Modeling and Variant Design

open access: yesAdvanced Science, EarlyView.
In this study, a computational pipeline is developed to systematically evaluate the conformational stability, disulfide bond reduction state, and aggregation and degradation tendencies of an anticancer VHH‐Fc fusion antibody. Based on the mechanistic insights, antibody variants with enhanced stability and increased yield are successfully designed. This
Yuan Fang   +10 more
wiley   +1 more source

The conversion of L-histidine to glutamic acid by liver enzymes [PDF]

open access: yes, 1952
Edlbacher and Neber (1) showed in 1934 that the liver enzyme named histidase degrades histidine to NH3, formic acid, and an unknown product which on further treatment with strong alkali yields glutamic acid.
Abrams, Adolph, Borsook, Henry
core  

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

open access: yesAdvanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang   +11 more
wiley   +1 more source

Thermal Synthesis of Polypeptides from N-Butyloxycarbonyl Oligopeptides Containing Aspartyl Residue at C-Terminus

open access: yesInternational Journal of Polymer Science, 2017
The thermal reactions of amino acids have been investigated for pure organic synthesis, materials preparation in industry, and prebiotic chemistry. N-t-Butyloxycarbonyl aspartic acid (Boc-Asp) releases 2-butene and carbon dioxide upon heating without ...
Toratane Munegumi, Takafumi Yamada
doaj   +1 more source

Antimitotic action of cornin as a biologically active polypeptide. I. Biochemical properties of cornin [PDF]

open access: yes, 1965
We succeeded in the extraction of a substance from beef cornea and rabbit muscle, that markedly inhibits mitosis of sea urchin eggs. The substance extracted from beef cornea is non-dialysable and it can be separated into three fractions by DEAE-cellulose
Murakami, Tetuhide H., Nisida, Isamu
core   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang   +4 more
wiley   +1 more source

The Equilibrium between l-Aspartic Acid, Fumaric Acid and Ammonia in Presence of Resting Bacteria.

open access: yesBiochemical Journal
IT is an old observation that when fumaric acid, maleic acid or malic acid is heated in the presence of ammonia in a sealed tube to 2000 a conversion to aspartic acid occurs.
J. H. Quastel, Barnet Woolf
semanticscholar   +1 more source

ON APPLICATION OF ACETYLAMINOSICCINE ACID IN NEUROPEDIATRICS

open access: yesВопросы современной педиатрии, 2008
The article focuses on theoretical and practical aspects of using acetylaminosuccinic acid (cogitum) in neuropediatrics. General properties of amino acid drugs were discussed.
V.M. Studenikin   +2 more
doaj   +2 more sources

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