Results 121 to 130 of about 138,442 (297)

Generation of chiral olefins based on L-aspartic acid

, 1997
Schlachter I, Fröhlich R, Mattay J. Generation of chiral olefins based on L-aspartic acid. Journal für praktische Chemie. 1997;339(1):66-70.A new chiral olefin 4 was synthesized starting from L-aspartic acid.
Mattay, Jochen, Schlachter, I, Fröhlich, R   +2 more
core   +1 more source

Homo‐/Heterodimeric Substrates Bias the Type and Multiplicity of Hydroxamic Acid Chelators Assembled by a NIS Synthetase DesD

Chemistry – A European Journal, EarlyView.
Chemoenzymatic reactions using the siderophore synthetase DesD from Salinispora tropica and hydroxamic acid substrates (native, non‐native) with different multiplicities (monomer, dimer) and components (homo‐/heterodimer) followed different reaction trajectories, which biased the architectures of the chelator major products and indicated DesD contains ...
Callum A. Rosser, Todd E. Markham, Rachel Codd   +2 more
wiley   +1 more source

Chiral asymmetric structures in aspartic acid and valine crystals assessed by atomic force microscopy

, 2016
Sem informaçãoStructures of crystallized deposits formed by the molecular self-assembly of aspartic acid and valine on silicon substrates were imaged by atomic force microscopy.
Teschke, O., Soares, D. M.
core   +1 more source

Late‐Stage Modification of Halotryptophan‐Containing Peptides Via Negishi Cross‐Coupling

Chemistry – A European Journal, EarlyView.
Negishi cross‐coupling provides access to the late‐stage functionalization of bromotryptophan‐containing peptides under comparatively mild conditions and is applicable to a range of peptide substrates in the investigated model systems. The examined alkyl iodides and variation of N‐terminal residues demonstrate the feasibility of the transformation in a
Laura Cerveson, Marcel‐Jannik Heldt, Norbert Sewald   +2 more
wiley   +1 more source

Multiomics reveals microbial metabolites as key actors in intestinal fibrosis in Crohn’s disease

EMBO Molecular Medicine
Intestinal fibrosis is the primary cause of disability in patients with Crohn’s disease (CD), yet effective therapeutic strategies are currently lacking.
Xuehua Li, Shixian Hu, Xiaodi Shen, Ruonan Zhang, Caiguang Liu, Lin Xiao, Jinjiang Lin, Li Huang, Weitao He, Xinyue Wang, Lili Huang, Qingzhu Zheng, Luyao Wu, Canhui Sun, Zhenpeng Peng, Minhu Chen, Ziping Li, Rui Feng, Yijun Zhu, Yangdi Wang, Zhoulei Li, Ren Mao, Shi-Ting Feng   +22 more
doaj   +1 more source

A quadratic multinomial regression model was established for taste properties of main catechins and amino acid monomers in green tea

Shipin yu jixie
ObjectiveTo study the flavor intensity of green tea after mixing the main flavor monomers.MethodsThree main catechins [epigallocatechin gallate (EGCG), epigallocatechin gallate (GCG), epicatechin gallate (ECG)] and three amino acid monomers (aspartic ...
RAN Qiansong, LIU Zhongying, LIU Xi, HOU Yanshuang, BAO Fushu, PAN Ke   +5 more
doaj   +1 more source

De Novo Design of Multivalent α/β‐Peptides Mimicking Transcription Factors Targeting the CBP KIX Domain

Chemistry – A European Journal, EarlyView.
A modular, de novo α/β‐peptide design strategy allows fine‐tuning of ligand properties, resulting in multivalent ligands that simultaneously target separate binding sites on the protein surface. ABSTRACT Protein‐protein interactions that regulate gene expression in the nucleus are increasingly recognized as potential therapeutic targets but present ...
Márk V. Tresztián, Vencel L. Petrovicz, Edit Wéber, Tamás A. Martinek, Zsófia Hegedüs   +4 more
wiley   +1 more source

Covalent attachment of aspartic acid to yeast aspartyl-tRNA synthetase induced by the enzyme

, 1982
Aspartic acid can be covalently linked to yeast aspartyl-tRNA synthetase and to other proteins, in the absence of tRNA, under conditions where the synthetase activates the amino acid into aspartyl-adenylate, i.e., in the presence of ATP and MgCl2.
D. Kern, R. Giegé, Giegé, R., Lorber, B., B. Lorber, Ebel, J.-P., Kern, D., J.-P. Ebel   +7 more
core   +1 more source

Matrix‐Free Afterglow Carbon Dots: Synthetic Strategies, Luminescence Mechanisms, and Emerging Applications

Carbon Innovation, EarlyView.
This review systematically elucidates the luminescence mechanism, synthesis methods of matrix‐free afterglow carbon dots, and their application progress in information encryption, light‐emitting diodes, sensing, bioimaging, and tumor treatment, and finally, discusses the current challenges and future development directions. ABSTRACT Afterglow materials,
Yupeng Liu, Xiangxin Sun, Zhiqi Cai, Hanyi Zhang, Yiming Hao, Songnan Qu   +5 more
wiley   +1 more source

TPM-like manipulations exerted an antidepressant effect and regulated amino acid metabolism and GHR/IGF-1 pathway in the liver in adolescent female CUMS rats

Frontiers in Physiology
ObjectiveTo explore whether traditional-pediatric-massage-like (TPM-like) manipulations exert antidepressant effects and regulate amino acid metabolism and GHR/IGF-1 pathway in the liver from the liver-brain axis perspective in adolescent female CUMS ...
Shaoyun Zhao, Jiaxuan Gong, Rong Wu, Rong Wu, Ying Xiong, Yun Gu, Yun Gu, Yuhang Wang, Zhixiu Song   +8 more
doaj   +1 more source