Results 121 to 130 of about 2,639,770 (286)

The Synthesis of a Chiral β-Amino Acid Derivative by the Grignard Reaction of an Aspartic Acid Equivalent

, 2010
A novel synthetic route to chiral β-amino acid derivative has been developed by a Grignard reaction of 2,4,5-trifluo-rophenyl magnesium bromide with the Weinreb amide derivative of L-aspartic acid. The aspartic equivalent was synthesised from L-aspartic
Xiaohu Tao, Xianhua Pan, Xiaojiong Xu, Libo Ruan, Feng Liu, Xiaoke Wang, Xijiang Peng, Wenhua Ou, Jiaomei Wan, Wansheng Yu, Yiming Li, Jun Mao   +11 more
core   +1 more source

Discovery of an Antiviral Electron Transfer Process to Create Catalytically Self‐Sufficient Viral Restriction Factors

Angewandte Chemie International Edition, EarlyView.
CYB5R3 is identified as a putative electron‐transfer partner of viperin (RSAD2), explaining why ER localisation is required for antiviral activity. Its utilisation enabled the engineering of immune‐silent, catalytically self‐sufficient antiviral restriction factor enzymes (iCAREs) that produce an antiviral nucleoside triphosphate analogue (ANTA ...
Mengdi Wu, Nghi Thao Hoang, Deborah Grifagni, Meritxell Wu‐Lu, Yujie Sheng, Theo Situmorang, Pei‐Hsin Tai, Zheng Chen, Astrid Maluta, Mohammed Hakil, Bianca Susini, Hannah Florance, Peter‐Leon Hagedoorn, John Mark Sutton, Maria‐Andrea Mroginski, Simone Ciofi‐Baffoni, Kourosh H. Ebrahimi   +16 more
wiley   +1 more source

Towards the directed evolution of an L-aspartate oxidase from Pseudomonas putida [PDF]

, 2012
Amino acid oxidases (AAOs) are enantioselective flavoenzymes that catalyse the oxidation of amino acids into imino acids, which spontaneously hydrolyse in water to form keto acids. AAOs have several potential applications, most notably as biocatalysts in
Leese, Charlotte
core   +1 more source

A quadratic multinomial regression model was established for taste properties of main catechins and amino acid monomers in green tea

Shipin yu jixie
ObjectiveTo study the flavor intensity of green tea after mixing the main flavor monomers.MethodsThree main catechins [epigallocatechin gallate (EGCG), epigallocatechin gallate (GCG), epicatechin gallate (ECG)] and three amino acid monomers (aspartic ...
RAN Qiansong, LIU Zhongying, LIU Xi, HOU Yanshuang, BAO Fushu, PAN Ke   +5 more
doaj   +1 more source

pH-sensitive binding of nickel(II) ions to aspartic acid [PDF]

, 2004
Agius R. pH-sensitive binding of nickel(II) ions to aspartic acid. Bielefeld (Germany): Bielefeld University; 2004.This study focuses on the thermodynamics and kinetics of the complexation of nickel(II) ions to aspartic acid (Asp), the building block of ...
Agius, Ronald
core  

Investigating the Synergistic Effects of Aspartic Acid and Tocopherol on Cytotoxicity and Oxidative Stress Caused by Etoposide on Hepg2 Cell Line by MTT and ROS Methods [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: Liver cancer ranks among the deadliest cancers globally. Etoposide, a chemotherapeutic agent frequently utilized in treatment, inhibits topoisomerase II, leading to cell cycle arrest and apoptosis induction. Nonetheless, etoposide generates
Mahboube Rahmati Kukandeh, Maryam Tangestanizadeh, Hourolein Arab, Elahe Gharehkhani, Mohammad Shokrzadeh   +4 more
doaj  

TPM-like manipulations exerted an antidepressant effect and regulated amino acid metabolism and GHR/IGF-1 pathway in the liver in adolescent female CUMS rats

Frontiers in Physiology
ObjectiveTo explore whether traditional-pediatric-massage-like (TPM-like) manipulations exert antidepressant effects and regulate amino acid metabolism and GHR/IGF-1 pathway in the liver from the liver-brain axis perspective in adolescent female CUMS ...
Shaoyun Zhao, Jiaxuan Gong, Rong Wu, Rong Wu, Ying Xiong, Yun Gu, Yun Gu, Yuhang Wang, Zhixiu Song   +8 more
doaj   +1 more source

Aspartic Acid [PDF]

, 2020
openaire   +1 more source

BIOTIN AND THE SYNTHESIS OF ASPARTIC ACID BY MICROORGANISMS [PDF]

Journal of Biological Chemistry, 1947
J L, STOKES, A, LARSEN, M, GUNNESS
openaire   +3 more sources

Proto‐Panic Modulation by Caffeine‐Proteinoid Complexes

Journal of Applied Polymer Science, EarlyView.
Caffeine–proteinoid microspheres synthesized by thermal polymerization exhibit compartmentalized drug loading with encapsulation efficiencies of 61%–82% and triphasic release kinetics. Electrochemical monitoring reveals multi‐scale oscillatory dynamics consistent with chaotic and damped harmonic behavior, while Boolean logic operations demonstrate ...
Panagiotis Mougkogiannis, Andrew Adamatzky   +1 more
wiley   +1 more source