Results 141 to 150 of about 138,442 (297)

Early gut microbial and metabolic dysregulation with subclinical cardiac alterations in a nonhuman primate model of Rett syndrome

open access: yesiMeta, EarlyView.
Longitudinal multi‐omics profiling of a nonhuman primate Rett syndrome (RTT) model reveals early systemic alterations. RTT monkeys exhibited postnatal growth retardation, intestinal structural abnormalities, and low‐grade systemic inflammation. Gut microbiome analysis showed delayed microbial maturation and age‐discordant dysbiosis, including altered ...
Ting Zhang   +8 more
wiley   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza   +2 more
wiley   +1 more source

pH-sensitive binding of nickel(II) ions to aspartic acid

open access: yes, 2004
Agius R. pH-sensitive binding of nickel(II) ions to aspartic acid. Bielefeld (Germany): Bielefeld University; 2004.This study focuses on the thermodynamics and kinetics of the complexation of nickel(II) ions to aspartic acid (Asp), the building block of ...
Agius, Ronald
core  

Intelligent design of artificial biocatalyst for biomedical diseases

open access: yesJournal of Intelligent Medicine, EarlyView.
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang   +3 more
wiley   +1 more source

Total synthesis of a peptide diatom sex pheromone bearing an unusual sulfated aspartic acid

open access: yes
The peptide Sex Inducing Pheromone SIP+ bearing an unusual sulfated aspartic acid residue induces sexual reproduction in diatom populations. Herein, we report the first total synthesis of SIP+ using both a sulfated building block approach and a SPPS ...
Andrew M., White   +3 more
core   +1 more source

Macronutrient and micronutrient profiles of meat types: insights into human health and diet

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Despite considerable advances in global health and nutrition, emerging challenges such as population growth, climate change, and limited natural resources continue to threaten food security. Meat remains an essential component of the human diet, supplying high‐quality proteins, essential amino acids, lipids, vitamins, and minerals necessary ...
Özgül Anitaş   +4 more
wiley   +1 more source

Ohmic heating dominates and ultrasound modulates aquafaba structure: A combined approach to design stable plant‐based emulsions

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND This study investigated the individual and combined effects of ohmic heating (OH, 20 and 40 V cm−1) and ultrasound (US, 425 and 850 W) on the chemical, physicochemical, and technological properties of chickpea aquafaba (AF) and its emulsions.
Débora Krichanã   +12 more
wiley   +1 more source

Investigation of the Electrochemical Behavior of Catechol in Presence of Glycine, Aspartic acid and Glutamic acid

open access: yes, 2016
This thesis is submitted to the Department of Chemistry, Khulna University of Engineering & Technology in partial fulfillment of the requirements for the degree of Master of Science in Chemistry, July 2016.Cataloged from PDF Version of Thesis.Includes ...
Uddin, Md. Nazim
core  

Bromelain as the enzyme of the future: A global bibliometric mapping of its applications and emerging trends

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract INTRODUCTION Bromelain, a complex mixture of proteolytic enzymes primarily extracted from plants of the Bromeliaceae family, has gained prominence because of its broad industrial applicability, particularly in the food, pharmaceutical and cosmetic sectors.
Genésio José da Silva Neto   +6 more
wiley   +1 more source

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